Statistics in Toxicology Using R

Statistics in Toxicology Using R PDF Author: Ludwig A. Hothorn
Publisher: CRC Press
ISBN: 1498786758
Category : Mathematics
Languages : en
Pages : 294

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Book Description
The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover, recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas, Statistics in Toxicology Using R explains the statistical analysi

Statistics in Toxicology Using R

Statistics in Toxicology Using R PDF Author: Ludwig A. Hothorn
Publisher: CRC Press
ISBN: 1498786758
Category : Mathematics
Languages : en
Pages : 294

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Book Description
The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover, recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas, Statistics in Toxicology Using R explains the statistical analysi

Computational Statistics with R

Computational Statistics with R PDF Author:
Publisher: Elsevier
ISBN: 044463441X
Category : Mathematics
Languages : en
Pages : 413

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Book Description
R is open source statistical computing software. Since the R core group was formed in 1997, R has been extended by a very large number of packages with extensive documentation along with examples freely available on the internet. It offers a large number of statistical and numerical methods and graphical tools and visualization of extraordinarily high quality. R was recently ranked in 14th place by the Transparent Language Popularity Index and 6th as a scripting language, after PHP, Python, and Perl. The book is designed so that it can be used right away by novices while appealing to experienced users as well. Each article begins with a data example that can be downloaded directly from the R website. Data analysis questions are articulated following the presentation of the data. The necessary R commands are spelled out and executed and the output is presented and discussed. Other examples of data sets with a different flavor and different set of commands but following the theme of the article are presented as well. Each chapter predents a hands-on-experience. R has superb graphical outlays and the book brings out the essentials in this arena. The end user can benefit immensely by applying the graphics to enhance research findings. The core statistical methodologies such as regression, survival analysis, and discrete data are all covered. - Addresses data examples that can be downloaded directly from the R website - No other source is needed to gain practical experience - Focus on the essentials in graphical outlays

Analyzing Baseball Data with R, Second Edition

Analyzing Baseball Data with R, Second Edition PDF Author: Jim Albert
Publisher: CRC Press
ISBN: 1351107089
Category : Mathematics
Languages : en
Pages : 361

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Book Description
Analyzing Baseball Data with R Second Edition introduces R to sabermetricians, baseball enthusiasts, and students interested in exploring the richness of baseball data. It equips you with the necessary skills and software tools to perform all the analysis steps, from importing the data to transforming them into an appropriate format to visualizing the data via graphs to performing a statistical analysis. The authors first present an overview of publicly available baseball datasets and a gentle introduction to the type of data structures and exploratory and data management capabilities of R. They also cover the ggplot2 graphics functions and employ a tidyverse-friendly workflow throughout. Much of the book illustrates the use of R through popular sabermetrics topics, including the Pythagorean formula, runs expectancy, catcher framing, career trajectories, simulation of games and seasons, patterns of streaky behavior of players, and launch angles and exit velocities. All the datasets and R code used in the text are available online. New to the second edition are a systematic adoption of the tidyverse and incorporation of Statcast player tracking data (made available by Baseball Savant). All code from the first edition has been revised according to the principles of the tidyverse. Tidyverse packages, including dplyr, ggplot2, tidyr, purrr, and broom are emphasized throughout the book. Two entirely new chapters are made possible by the availability of Statcast data: one explores the notion of catcher framing ability, and the other uses launch angle and exit velocity to estimate the probability of a home run. Through the book’s various examples, you will learn about modern sabermetrics and how to conduct your own baseball analyses. Max Marchi is a Baseball Analytics Analyst for the Cleveland Indians. He was a regular contributor to The Hardball Times and Baseball Prospectus websites and previously consulted for other MLB clubs. Jim Albert is a Distinguished University Professor of statistics at Bowling Green State University. He has authored or coauthored several books including Curve Ball and Visualizing Baseball and was the editor of the Journal of Quantitative Analysis of Sports. Ben Baumer is an assistant professor of statistical & data sciences at Smith College. Previously a statistical analyst for the New York Mets, he is a co-author of The Sabermetric Revolution and Modern Data Science with R.

Statistics in Toxicology

Statistics in Toxicology PDF Author: Byron J. T. Morgan
Publisher: Oxford University Press
ISBN: 9780198523291
Category : Mathematics
Languages : en
Pages : 250

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Book Description
This collection of papers on aspects of statistics in toxicology is will be of interest to all medical statisticians. It offers findings from numerous leading experts from around the world including A. Whitehead and R. N. Connor (University of Reading), L. Ryan (Harvard), A. P. Grieve (Pfizer Research), K.J. Risko (Northern Telecom), and B.H. Margolin (University of North Carolina). This is the latest in the popular Royal Statistical Society Lecture Series, and will be essential reading for all those involved in this area.

R Primer

R Primer PDF Author: Claus Thorn Ekstrom
Publisher: CRC Press
ISBN: 1351650459
Category : Mathematics
Languages : en
Pages : 379

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Book Description
Newcomers to R are often intimidated by the command-line interface, the vast number of functions and packages, or the processes of importing data and performing a simple statistical analysis. The R Primer provides a collection of concise examples and solutions to R problems frequently encountered by new users of this statistical software. This new edition adds coverage of R Studio and reproducible research.

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools PDF Author:
Publisher: Academic Press
ISBN: 0128137258
Category : Technology & Engineering
Languages : en
Pages : 1055

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Book Description
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

Statistical Models in Toxicology

Statistical Models in Toxicology PDF Author: Mehdi Razzaghi
Publisher: CRC Press
ISBN: 0429532350
Category : Mathematics
Languages : en
Pages : 182

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Book Description
Statistical Models in Toxicology presents an up-to-date and comprehensive account of mathematical statistics problems that occur in toxicology. This is as an exciting time in toxicology because of the attention given by statisticians to the problem of estimating the human health risk for environmental and occupational exposures. The development of modern statistical techniques with solid mathematical foundations in the 20th century and the advent of modern computers in the latter part of the century gave way to development of many statistical models and methods to describe toxicological processes and attempts to solve the associated problems. Not only have the models enjoyed a high level of elegance and sophistication mathematically, they are widely used by industry and government regulatory agencies. Features: Focuses on describing the statistical models in environmental toxicology that facilitate the assessment of risk mainly in humans. The properties and shortfalls of each model are discussed and its impact in the process of risk assessment is examined. Discusses models that assess the risk of mixtures of chemicals. Presents statistical models that are developed for risk estimation in different aspects of environmental toxicology including cancer and carcinogenic substances. Includes models for developmental and reproductive toxicity risk assessment, risk assessment in continuous outcomes and developmental neurotoxicity. Contains numerous examples and exercises. Statistical Models in Toxicology introduces a wide variety of statistical models that are currently utilized for dose-response modeling and risk analysis. These models are often developed based on design and regulatory guidelines of toxicological experiments. The book is suitable for practitioners or as use as a textbook for advanced undergraduate or graduate students of mathematics and statistics.

Testing R Code

Testing R Code PDF Author: Richard Cotton
Publisher: CRC Press
ISBN: 1498763669
Category : Computers
Languages : en
Pages : 196

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Book Description
Learn how to write R code with fewer bugs. The problem with programming is that you are always one typo away from writing something silly. Likewise with data analysis, a small mistake in your model can lead to a big mistake in your results. Combining the two disciplines means that it is all too easy for a missed minus sign to generate a false prediction that you don’t spot until it’s too late. Testing is the only way to be sure that your code, and your results, are correct. Testing R Code teaches you how to perform development-time testing using the testthat package, allowing you to ensure that your code works as intended. The book also teaches run-time testing using the assertive package; enabling your users to correctly run your code. After beginning with an introduction to testing in R, the book explores more advanced cases such as integrating tests into R packages; testing code that accesses databases; testing C++ code with Rcpp; and testing graphics. Each topic is explained with real-world examples, and has accompanying exercises for readers to practise their skills — only a small amount of experience with R is needed to get started!

Reproducible Finance with R

Reproducible Finance with R PDF Author: Jonathan K. Regenstein, Jr.
Publisher: CRC Press
ISBN: 1351052608
Category : Mathematics
Languages : en
Pages : 248

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Book Description
Reproducible Finance with R: Code Flows and Shiny Apps for Portfolio Analysis is a unique introduction to data science for investment management that explores the three major R/finance coding paradigms, emphasizes data visualization, and explains how to build a cohesive suite of functioning Shiny applications. The full source code, asset price data and live Shiny applications are available at reproduciblefinance.com. The ideal reader works in finance or wants to work in finance and has a desire to learn R code and Shiny through simple, yet practical real-world examples. The book begins with the first step in data science: importing and wrangling data, which in the investment context means importing asset prices, converting to returns, and constructing a portfolio. The next section covers risk and tackles descriptive statistics such as standard deviation, skewness, kurtosis, and their rolling histories. The third section focuses on portfolio theory, analyzing the Sharpe Ratio, CAPM, and Fama French models. The book concludes with applications for finding individual asset contribution to risk and for running Monte Carlo simulations. For each of these tasks, the three major coding paradigms are explored and the work is wrapped into interactive Shiny dashboards.

Statistics for Toxicologists

Statistics for Toxicologists PDF Author: Salsburg
Publisher: CRC Press
ISBN: 9780824775902
Category : Mathematics
Languages : en
Pages : 220

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Book Description
This book explains how the computer programs work and why and when they can be applied to problems in toxicology. It discusses the statistical models used and their applications in a general fashion. The book overviews the problems that can arise from the blind use of the statistical models.