Spotlight on Potassium Channels and Their Modulation PDF Download
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Author: Edward Carmeliet
Publisher:
ISBN:
Category :
Languages : en
Pages : 151
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Book Description
Author: Edward Carmeliet
Publisher:
ISBN:
Category :
Languages : en
Pages : 151
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Book Description
Author: John M Evans
Publisher: CRC Press
ISBN: 1482272849
Category : Medical
Languages : en
Pages : 449
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Book Description
Potassium ions K+ ions are vital in physiological processes, particularly with regard to the cardiovascular system. Modulators influence the channels through which these ions flow and the research into modulator drugs of these channels is the subject of rapidly-advancing research. This work is intended to be of use as a tool for those working in th
Author: Valentin K. Gribkoff
Publisher: John Wiley & Sons
ISBN: 0470429895
Category : Science
Languages : en
Pages : 505
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Book Description
This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.
Author: Hailin Zhang
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Jonathan D. Lippiat
Publisher: Humana Press
ISBN: 9781617379406
Category : Medical
Languages : en
Pages : 0
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Book Description
Due to the importance of potassium channels in cellular function, researchers have been challenged to develop tools and experimental procedures to probe the function and identify chemicals that modulate the behaviour of this super-family of ion channels. In Potassium Channels: Methods and Protocols, experts in the field present a range of experimental approaches that have been developed to investigate potassium channel structure, function, pharmacology, cell biology, gene expression, and their role in disease. Many of these techniques study potassium channels as cellular proteins as well as the resultant membrane biophysics. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters contain brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Potassium Channels: Methods and Protocols provides a wide range of approaches in order to aid current research projects and inspire new investigations.
Author: Hugh Malcolm Chapman
Publisher:
ISBN:
Category :
Languages : en
Pages : 316
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Book Description
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1796
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Book Description
Author: Bernard Swynghedauw
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 718
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Book Description
Cardiac insufficiency, a major cause of premature mortality, is a key focus of medical and pharmaceutical research. This book aims to bring clinicians and researchers up-to-date on recent biophysical, cellular physiological and molecular biological developments and their clinical applications.
Author: Hiromu Yawo
Publisher: Springer Nature
ISBN: 9811587639
Category : Medical
Languages : en
Pages : 648
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Book Description
This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
Author: Nikita Gamper
Publisher: Springer Nature
ISBN: 3030840522
Category : Medical
Languages : en
Pages : 546
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Book Description
The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology.
