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Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author: Wim E. Crusio
Publisher: Cambridge University Press
ISBN: 1107355575
Category : Science
Languages : en
Pages : 361
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Book Description
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author: Paul C. Guest
Publisher: Humana Press
ISBN: 9781493989935
Category : Medical
Languages : en
Pages : 343
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Book Description
This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas.
Author: William N. Dember
Publisher: Springer Science & Business Media
ISBN: 1461388791
Category : Psychology
Languages : en
Pages : 300
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Book Description
A wide variety of species, including human beings, exhibits a remarkably reliable behavior pattern, known as spontaneous alternation behavior (SAB), that has intrigued researchers for over seven decades. Though the details may vary depending on species and setting, SAB essentially entails first choosing one member of a pair of alternatives and then the other, without instructions or incen tives to do so. Spontaneous alternation is manifested even in the early trials of a discrimination-learning experiment, where only one of the choices is reinforced. Indeed, that was the setting in which SAB was first noted (Hunter, 1914). Rein forcement contingencies, evidently, are superimposed, not on a random sequence of choices, but on a potent, systematic behavior pattern. This book is the first to be devoted entirely to SAB and closely related phenomena, such as habituation and exploration. The literature on SAB is vast, covering a host of questions ranging from the cues that guide alternation to its phylogenetic and ontogenetic generality, its relation to learning and motivation, and its neurochemical substrates. In separate chapters we take up each of the major issues, reviewing what is known about the several facets of SAB and revealing areas of ignorance. The chapter authors were encouraged to discuss their own research where pertinent, some of it as yet unpublished, indeed some conducted specifically for this volume.
Author:
Publisher: Academic Press
ISBN: 0128120142
Category : Medical
Languages : en
Pages : 602
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Book Description
Handbook of Object Novelty Recognition, Volume 26, synthesizes the empirical and theoretical advances in the field of object recognition and memory that have occurred since the development of the spontaneous object recognition task. The book is divided into four sections, covering vision and perception of object features and attributions, definitions of concepts that are associated with object recognition, the influence of brain lesions and drugs on various memory functions and processes, and models of neuropsychiatric disorders based on spontaneous object recognition tasks. A final section covers genetic and developmental studies and gender and hormone studies. - Details the brain structures and the neural circuits that underlie memory of objects, including vision and olfaction - Provides a thorough description of the object novelty recognition task, variations on the basic task, and methods and techniques to help researchers avoid common pitfalls - Assists researchers in understanding all aspects of object memory, conducting object novelty recognition tests, and producing reliable, reproducible results
Author: Allison B. Kaufman
Publisher: Cambridge University Press
ISBN: 110856125X
Category : Psychology
Languages : en
Pages : 1032
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Book Description
This handbook lays out the science behind how animals think, remember, create, calculate, and remember. It provides concise overviews on major areas of study such as animal communication and language, memory and recall, social cognition, social learning and teaching, numerical and quantitative abilities, as well as innovation and problem solving. The chapters also explore more nuanced topics in greater detail, showing how the research was conducted and how it can be used for further study. The authors range from academics working in renowned university departments to those from research institutions and practitioners in zoos. The volume encompasses a wide variety of species, ensuring the breadth of the field is explored.
Author: B.F Skinner
Publisher: Simon and Schuster
ISBN: 1476716153
Category : Psychology
Languages : en
Pages : 484
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Book Description
The psychology classic—a detailed study of scientific theories of human nature and the possible ways in which human behavior can be predicted and controlled—from one of the most influential behaviorists of the twentieth century and the author of Walden Two. “This is an important book, exceptionally well written, and logically consistent with the basic premise of the unitary nature of science. Many students of society and culture would take violent issue with most of the things that Skinner has to say, but even those who disagree most will find this a stimulating book.” —Samuel M. Strong, The American Journal of Sociology “This is a remarkable book—remarkable in that it presents a strong, consistent, and all but exhaustive case for a natural science of human behavior…It ought to be…valuable for those whose preferences lie with, as well as those whose preferences stand against, a behavioristic approach to human activity.” —Harry Prosch, Ethics
Author: Ulrich Dirnagl
Publisher: Humana Press
ISBN: 9781607617495
Category : Medical
Languages : en
Pages : 0
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Book Description
In view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated. When methods of systematic review and metaanalyis are applied, however, it turns out that experimental models actually faithfully predicted the negative outcomes of clinical trials. In addition, thrombolysis and neuroprotection by hypothermia, first described in animal models, are key examples of treatment modalities that have made it successfully into clinical practice. In Rodent Models of Stroke, an international consortium of authors aims at critically addressing the issues on a very practical level, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. The structure and content of the book reflect both the authors’ longstanding expertise in experimental and clinical stroke research and their roles in training the scientific community in the tools of the trade. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used, well-honed approaches in the field today. Stimulating and easy-to-use, Rodent Models of Stroke will help its readers understand the limitations and the opportunities of modeling stroke in rodents and enable them to conduct experiments which will not only improve our understanding of the pathophysiology of this devastating disorder but also serve as the basis for developing new highly effective treatments.
Author: B. F. Skinner
Publisher: B. F. Skinner Foundation
ISBN: 0989983951
Category : Psychology
Languages : en
Pages : 794
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Book Description
The contingent relationship between actions and their consequences lies at the heart of Skinner’s experimental analysis of behavior. Particular patterns of behavior emerge depending upon the contingencies established. Ferster and Skinner examined the effects of different schedules of reinforcement on behavior. An extraordinary work, Schedules of Reinforcement represents over 70,000 hours of research primarily with pigeons, though the principles have now been experimentally verified with many species including human beings. At first glance, the book appears to be an atlas of schedules. And so it is, the most exhaustive in existence. But it is also a reminder of the power of describing and explaining behavior through an analysis of measurable and manipulative behavior-environment relations without appealing to physiological mechanisms in the brain. As en exemplar and source for the further study of behavioral phenomena, the book illustrates the scientific philosophy that Skinner and Ferster adopted: that a science is best built from the ground up, from a firm foundation of facts that can eventually be summarized as scientific laws.
Author: G. Buzsáki
Publisher: Oxford University Press
ISBN: 0199828237
Category : Medical
Languages : en
Pages : 465
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Book Description
Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.
