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Author: John Huxtable Elliott
Publisher: Yale University Press
ISBN: 0300160011
Category : History
Languages : en
Pages : 343
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Book Description
When J. H. Elliott published Spain and Its World, 1500?1700 some twenty years ago, one of many enthusiasts declared, ?For anyone interested in the history of empire, of Europe and of Spain, here is a book to keep within reach, to read, to study and to enjoy" (Times Literary Supplement). Since then Elliott has continued to explore the history of Spain and the Hispanic world with originality and insight, producing some of the most influential work in the field. In this new volume he gathers writings that reflect his recent research and thinking on politics, art, culture, and ideas in Europe and the colonial worlds between 1500 and 1800.The volume includes fourteen essays, lectures, and articles of remarkable breadth and freshness, written with Elliott's characteristic brio. It includes an unpublished lecture in honor of the late Hugh Trevor-Roper. Organized around three themes?early modern Europe, European overseas expansion, and the works and historical context of El Greco, Velzquez, Rubens, and Van Dyck?the book offers a rich survey of the themes at the heart of Elliott's interests throughout a career distinguished by excellence and innovation.
Author: John Huxtable Elliott
Publisher: Yale University Press
ISBN: 0300160011
Category : History
Languages : en
Pages : 343
Get Book Here
Book Description
When J. H. Elliott published Spain and Its World, 1500?1700 some twenty years ago, one of many enthusiasts declared, ?For anyone interested in the history of empire, of Europe and of Spain, here is a book to keep within reach, to read, to study and to enjoy" (Times Literary Supplement). Since then Elliott has continued to explore the history of Spain and the Hispanic world with originality and insight, producing some of the most influential work in the field. In this new volume he gathers writings that reflect his recent research and thinking on politics, art, culture, and ideas in Europe and the colonial worlds between 1500 and 1800.The volume includes fourteen essays, lectures, and articles of remarkable breadth and freshness, written with Elliott's characteristic brio. It includes an unpublished lecture in honor of the late Hugh Trevor-Roper. Organized around three themes?early modern Europe, European overseas expansion, and the works and historical context of El Greco, Velzquez, Rubens, and Van Dyck?the book offers a rich survey of the themes at the heart of Elliott's interests throughout a career distinguished by excellence and innovation.
Author: Patricia E. Grieve
Publisher: JHU Press
ISBN: 0801890365
Category : History
Languages : en
Pages : 329
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Book Description
Finally, Grieve focuses on the misogynistic elements of the story and asks why the fall of Spain is figured as a cautionary tale about a woman's sexuality.
Author: Melanie Little
Publisher: Annick Press
ISBN: 1554512948
Category : Juvenile Fiction
Languages : en
Pages : 379
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Book Description
Fifteenth-century Spain is a richly multicultural society in which Jews, Muslims, and Christians coexist. But under the zealous Christian Queen Isabella, the country abruptly becomes one of the most murderously intolerant places on Earth. It is in this atmosphere that the Benvenistes, a family of scribes, attempt to eke out a living. The family has a secret—they are conversos: Jews who converted to Christianity. Now, with neighbors and friends turned into spies, fear hangs in the air. One day a young man is delivered to their door. His name is Amir, and he wears the robe and red patch of a Muslim. Fifteen-year-old Ramon Benveniste broods over Amir’s easy acceptance into the family. Startling and dramatic events overtake the household, and the family is torn apart. One boy becomes enslaved, the other takes up service for the Inquisitors. Finally, their paths cross again in a stunningly haunting scene.
Author: Janice Eberly
Publisher: Brookings Institution Press
ISBN: 0815738161
Category : Business & Economics
Languages : en
Pages : 492
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Book Description
Brookings Papers on Economic Activity (BPEA) provides academic and business economists, government officials, and members of the financial and business communities with timely research on current economic issues. Contents: On Secular Stagnation in the Industrialized World, Lukasz Rachel and Lawrence H. Summers A Forensic Examination of China's National Accounts, Wei Chen, Xilu Chen, Chang-Tai Hsieh, and Zheng Song A Unified Approach to Measuring u*, Richard K. Crump, Stefano Eusepi, Maric Giannoni, and Ays ̧egül S ̧ahin Fiscal Space and the Aftermath of Financial Crises: How It Matters and Why, Christina D. Romer and David H. Romer Okun Revisited: Who Benefits Most from a Strong Economy? Stephanies R. Aaronson, Mary C. Daly, William L. Wascher, and David W. Wilcox On the Economics of a Carbon Tax for the United States, Gilbert E. Metcalf
Author: Amy Rosenberg
Publisher: Springer
ISBN: 1493925431
Category : Medical
Languages : en
Pages : 384
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Book Description
“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases that possess acceptable safety and efficacy profiles, these products have generally not been reexamined and modified for an improved clinical performance, with enhancements both to safety and efficacy profiles. Advances in protein engineering, coupled with greatly enhanced understanding of critical product quality attributes for efficacy and safety, make it possible to optimize predecessor products for clinical performance, thereby enhancing patient quality of life and with the potential for great savings in health care costs. Yet despite such knowledge, there is little movement towards such modifications. This book examines engineering protein therapeutic products such that they exhibit an optimal, not just an adequate, clinical performance profile. Two product classes, therapeutic enzymes for lysosomal storage diseases (enzyme replacement therapies, ERT) and monoclonal antibodies (mAbs), are used as examples of what modifications to such proteins could be made to enhance clinical performance, “closer to a cure” as it were. For ERT, the key to optimizing clinical performance is to ensure the ERT is endowed with moieties that target the protein to the relevant target tissue. Thus, for Gaucher Disease, our best example of how to optimize an ERT to address a disease that manifests in specific target tissues (macrophages and monocytes), the enzyme has been extensively modified to target macrophages. For diseases such as Pompe Disease, largely a disorder of muscle, optimal performance of ERT will depend on endowing the enzyme with the ability to be taken up via the Mannose 6 Phosphate Receptor, and so one of the chapters in the book will discuss such approaches. Moreover, a major failure of biotechnology based products is to gain access to the CNS, a key target tissue in numerous diseases. Thus, a chapter has been devoted to strategies to access the CNS. Additionally, immune responses to therapeutic proteins can be highly problematic, eliminating the efficacy of life saving or highly effective protein therapeutics. This is especially poignant in the case of Pompe Disease wherein great improvement in muscle strength and functionality is lost following development of an immune response to the ERT with consequent patient deterioration and death. Thus, a chapter regarding protein engineering, as well as other non-clinical approaches to diminishing immunogenicity is a valuable part of the book. Monoclonal antibodies (mAbs) can be engineered to bind targets relevant to a wide variety of diseases; binding affinity, however, is only part of the equation and one of the chapters will present a molecular assessment approach that balances affinity with pharmacokinetics and manufacturability. As with other proteins immunogenicity can be problematic, being responsible for loss of efficacy of anti-TNF mAbs, often after prolonged successful treatment. The authors will also share their perspective on the consequences of physico-chemical modifications occurring to mAbs once they reach the circulation or their target, a research area open to further development from a protein engineering as well as analytical perspective. This book will also discuss novel platforms for protein therapeutics, technologies that exceed mAbs with respect to potency, and hence, potentially efficacy. These platforms consist largely of repeat domain proteins with very high affinity for their target ligands, but while potentially more efficacious, immunogenicity may be a major problem limiting use. The economics surrounding the issue of biobetters is another high-profile issue - this final chapter will explore the incentives and disincentives for developing biobetters and consider incentives that might make their pursuit more rewarding.
Author: Bruce Hoffman
Publisher: Columbia University Press
ISBN: 0231537433
Category : Political Science
Languages : en
Pages : 695
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Book Description
Examining major terrorist acts and campaigns undertaken in the decade following September 11, 2001, internationally recognized scholars study the involvement of global terrorist leaders and organizations in these incidents and the planning, organization, execution, recruitment, and training that went into them. Their work captures the changing character of al-Qaeda and its affiliates since the invasions of Afghanistan and Iraq and the sophisticated elements that, despite the West's best counterterrorism efforts, continue to exert substantial direction over jihadist terrorist operations. Through case studies of terrorist acts and offensives occurring both in and outside the West, the volume's contributors investigate al-Qaeda and other related entities as they adapted to the strategies of Operation Enduring Freedom and subsequent U.S.-led global counterterrorism programs. They explore whether Osama bin Laden was indeed reduced to a mere figurehead before his death or continued to influence al-Qaeda's global activities. Did al-Qaeda become a loose collection of individuals and ideas following its expulsion from Afghanistan, or was it reborn as a transnational terrorist structure powered by a well-articulated ideology? What is the preeminent terrorist threat we face today, and what will it look like in the future? This anthology pinpoints the critical patterns and strategies that will inform counterterrorism in the coming decades.
Author: Fiona Handyside
Publisher: Springer
ISBN: 1137388927
Category : Performing Arts
Languages : en
Pages : 218
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Book Description
From the precocious charms of Shirley Temple to the box-office behemoth Frozen and its two young female leads, Anna and Elsa, the girl has long been a figure of fascination for cinema. The symbol of (imagined) childhood innocence, the site of intrigue and nostalgia for adults, a metaphor for the precarious nature of subjectivity itself, the girl is caught between infancy and adulthood, between objectification and power. She speaks to many strands of interest for film studies: feminist questions of cinematic representation of female subjects; historical accounts of shifting images of girls and childhood in the cinema; and philosophical engagements with the possibilities for the subject in film. This collection considers the specificity of girls' experiences and their cinematic articulation through a multicultural feminist lens which cuts across the divides of popular/art-house, Western/non Western, and north/south. Drawing on examples from North and South America, Asia, Africa, and Europe, the contributors bring a new understanding of the global/local nature of girlhood and its relation to contemporary phenomena such as post-feminism, neoliberalism and queer subcultures. Containing work by established and emerging scholars, this volume explodes the narrow post-feminist canon and expands existing geographical, ethnic, and historical accounts of cinematic cultures and girlhood.
Author: Maryellen Bieder
Publisher: Taylor & Francis
ISBN: 1134777167
Category : Literary Criticism
Languages : en
Pages : 257
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Book Description
The Spanish Civil War (1936-1939) pitted conservative forces including the army, the Church, the Falange (fascist party), landowners, and industrial capitalists against the Republic, installed in 1931 and supported by intellectuals, the petite bourgeoisie, many campesinos (farm laborers), and the urban proletariat. Provoking heated passions on both sides, the Civil War soon became an international phenomenon that inspired a number of literary works reflecting the impact of the war on foreign and national writers. While the literature of the period has been the subject of scholarship, women's literary production has not been studied as a body of work in the same way that literature by men has been, and its unique features have not been examined. Addressing this lacuna in literary studies, this volume provides fresh perspectives on well-known women writers, as well as less studied ones, whose works take the Spanish Civil War as a theme. The authors represented in this collection reflect a wide range of political positions. Writers such as Maria Zambrano, Mercè Rodoreda, and Josefina Aldecoa were clearly aligned with the Republic, whereas others, including Mercedes Salisachs and Liberata Masoliver, sympathized with the Nationalists. Most, however, are situated in a more ambiguous political space, although the ethics and character portraits that emerge in their works might suggest Republican sympathies. Taken together, the essays are an important contribution to scholarship on literature inspired by this pivotal point in Spanish history.
Author: Ben Douglas-Jones KC
Publisher: Bloomsbury Publishing
ISBN: 1526519526
Category : Law
Languages : en
Pages : 576
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Book Description
The law of human rights permeates every area of law. This title focuses on the impact of human rights law at every stage of the criminal process. It addresses the principal human rights issues that apply during an investigation and prior to a suspect knowing that they are a suspect, powers of arrest and search, and treatment at the police station. It considers every stage of the criminal process, including appeal before the domestic courts and the European Court of Human Rights. Part 1 covers the fundamental principles of the European Convention on Human Rights and the Human Rights Act 1998 and their application in domestic law, particularly in relation to criminal appeals, as well as taking a case to the European Court of Human Rights. Parts 2 to 4 address the three broad phases of a criminal case – investigation, pre-trial and trial – providing an analysis of human rights law as it applies in each phase. This book offers a comprehensive analysis of the often complex interactions between criminal law and human rights; with a wide range of experienced contributors drawn from the legal profession and academia, under the general editorship of Ben Douglas-Jones KC, Daniel Bunting, Paul Mason and Benjamin Newton.
Author: Peter Kennedy
Publisher: Routledge
ISBN: 1317981715
Category : Political Science
Languages : en
Pages : 152
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Book Description
As football clubs have become luxury investments, their decisions increasingly mirror those of any other business organisation. Football supporters have been encouraged to express their club loyalty by ‘thinking business’ - acting as consumers and generating money deemed necessary for their clubs to compete at the highest levels. In critical studies, supporters have been portrayed as passive or reluctant consumers who, imprisoned by enduring club loyalties, embody a fatalistic attitude to their own exploitation. As this book aims to show, however, such expressions of loyalty are far from hegemonic and often interface haphazardly with traditional ideas about what constitutes the ‘loyal fan’. While there is little doubt that professional football is experiencing commodification, the reality is that football clubs are not simply businesses, nor can they ever aspire to be organisations driven solely by expanding or protecting economic value. Rather, clubs hover uncertainly between being businesses and community assets. Football Supporters and the Commercialisation of Football explores the implications of this uncertainty for understanding supporter resistance to, and compromise with, commodification. Every club and its supporters exist in their own unique national and local contexts. In this respect, this book offers a Euro-wide comparison of supporter reactions to commercialisation and provides unique insight into how football supporters actively mediate regional, local and national contexts, as they intersect with the universalistic presumptions of commerce. This book was previously published as a special issue of Soccer and Society.
