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Author: Masanori Honsho
Publisher: Frontiers Media SA
ISBN: 2832514944
Category : Science
Languages : en
Pages : 244
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Book Description
Author: Masanori Honsho
Publisher: Frontiers Media SA
ISBN: 2832514944
Category : Science
Languages : en
Pages : 244
Get Book Here
Book Description
Author: Dayan Goodenowe
Publisher: Independently Published
ISBN:
Category :
Languages : en
Pages : 244
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Book Description
Breaking Alzheimer's is Dr. Dayan Goodenowe's story of personal and scientific perseverance. The biochemical mechanisms of neurological disease is his area of expertise and was his area of expertise for 15 years before he serendipitously discovered that low plasmalogen levels were causing Alzheimer's. Dr. Goodenowe had never heard of plasmalogens and he had never been taught about them. There are now 15 years of supportive validation of this discovery and access to plasmalogen testing and supplementation is now available to everyone. By sheer will, Dr. Goodenowe has completed the beginning and the middle of this journey such that the plasmalogen genie cannot be put back in the bottle. This book is about bringing the reader up to speed as to where we currently are on this journey and where we are going from here. The Breaking Alzheimer's Video Series and Audio Book will be available through Dr. Dayan Goodenowe's website soon. Learn more about Dr. Goodenowe and his educational content here: https: //drgoodenowe.com To learn more about Dr. Goodenowe's scientifically designed supplements and blood testing technology visit the Prodrome Sciences website here: https: //prodrome.com ADVANCE PRAISE "A paradigm-altering view of Alzheimer's." Dale Bredesen, MD Author of The New York Times Bestseller The End of Alzheimer's "A brilliant and ground-breaking text on the science and clinical application of plasmalogens for the therapeutic amelioration of Alzheimer's Dementia. I have had the good fortune of observing firsthand the significant, clinical benefits in my patients with neurodegenerative disorders for whom I've prescribed plasmalogen therapy." Mitchel Fleisher M.D., D.Ht., D.A.B.F.M., Dc.A.B.C.T. Medical Director, Center for Integrative & Regenerative Medicine "A bold and promising approach. Dr. Goodenowe has performed groundbreaking and compelling research which is detailed in the book so that afflicted patients and health professionals will become aware of a discovery which may very well change our approach to Alzheimer's. We have been deploying plasmalogen precursors at the Regenesis Project and have found that within the timeframe of a few weeks, people become more alert and cognizant." Sheldon Jordan, MD, FAAN, DABPN, DABCN Medical Director, the Regenesis Project "Dr. Goodenowe has not only identified a biomarker-plasmalogen-that is strongly correlated with dementia, but he has also discovered a way to track and improve that marker allowing ApoE4 carriers, at the highest genetic risk for Alzheimer's, to potentially avoid disease onset. Indeed, many of our members have had a noticeable improvement after addressing low levels." Julie Gregory Founder & President of ApoE4.Info "I strongly recommend this book which I hope will be as transformative for you as it has been for me. It is easy to read and understand and will impact your everyday decision making." Bijan Pourat MD ACC FRCP(C) "Dayan Goodenowe has drilled down to the very core of what makes us tick. His patient 25 year journey of research and invention has unpacked unique and marvelous understanding into how our metabolic engine works. We have a whole new field of medicine opening up called "metabolic medicine" and it runs right through Dr. Goodenowe's inventions. Like tuning your carburetor and timing your engine, we can now heal your mitochondria and make your peroxisomes whistle with the careful measurement and replacement of plasmalogens. The implications of his inventions can't be overstated. This is the end of Alzheimer's, Parkinson's, cancer....and who knows what lies ahead in the paradigm shift to true wellness with the absence of disease." John E. Whitcomb, MD Brookfield Longevity Medical Clinic
Author: Alessandra Sussulini
Publisher: Springer
ISBN: 3319476564
Category : Science
Languages : en
Pages : 353
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Book Description
This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.
Author: Don Rittner
Publisher: Infobase Publishing
ISBN: 1438109997
Category : Biology
Languages : en
Pages : 417
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Book Description
Contains approximately 800 alphabetical entries, prose essays on important topics, line illustrations, and black-and-white photographs.
Author: Uwe Theo Bornscheuer
Publisher: Wiley-Blackwell
ISBN:
Category : Science
Languages : en
Pages : 456
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Book Description
Enzymatic methods of lipid modification, particularly of fats and oils, have developed rapidly since the 1980s. In parallel to the rapid progress in research a wide range of applications have emerged, e.g. in the food industry. The book is written by leading experts in the field and reflects the state-of-the-art of enzymatic lipid modification. It provides the reader with guidelines how to select suitable enzymes and how to apply them efficiently. Applications of lipases and phospholipases, lipoxygenases and P450-monooxygenases and the use of whole-cell systems in lipid modification are described. Cloning, expression and mutagenesis as well as attempts to understand the molecular basis of specificity and stereoselectivity are outlined. In addition engineering aspects and the choice of solvent systems are addressed.
Author: Karoly Vekey
Publisher: Elsevier
ISBN: 0080554652
Category : Science
Languages : en
Pages : 607
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Book Description
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.
Author: Xianlin Han
Publisher: John Wiley & Sons
ISBN: 1118893123
Category : Science
Languages : en
Pages : 48
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Book Description
Covers the area of lipidomics from fundamentals and theory to applications Presents a balanced discussion of the fundamentals, theory, experimental methods and applications of lipidomics Covers different characterizations of lipids including Glycerophospholipids; Sphingolipids; Glycerolipids and Glycolipids; and Fatty Acids and Modified Fatty Acids Includes a section on quantification of Lipids in Lipidomics such as sample preparation; factors affecting accurate quantification; and data processing and interpretation Details applications of Lipidomics Tools including for Health and Disease; Plant Lipidomics; and Lipidomics on Cellular Membranes
Author: Fong-Fu Hsu
Publisher: Humana
ISBN: 9781071614099
Category : Science
Languages : en
Pages : 314
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Book Description
This detailed volume covers conventional MS-based “shotgun lipidomics” by which samples are introduced by infusion or loop injection, as well as LC-MS-based lipidomics, which are becoming increasingly important due to the ever-increasing demand for a complete and precise lipid analysis of the complex and diversified lipids in nature. The volume features protocols applying chemical reactions, the on-line photochemical reactions combined with various MS methods for comprehensive characterization of various lipid classes, and quantification of specific and rare lipids. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mass Spectrometry-Based Lipidomics: Methods and Protocols serves as an invaluable guide for biochemists and mass spectroscopists who are interested in lipid studies.
Author: Frank Roels
Publisher: Springer
ISBN: 9780306481741
Category : Medical
Languages : en
Pages : 429
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Book Description
In most peroxisomal disorders the nervous system is severely affected which explains the clinical and community burden they represent. This is the first book to focus not only on the mutations causing these inherited illnesses, but also on mechanisms that regulate, suppress or enhance expression of genes and their products (enzymes). Indeed since the success and completion of the Human Genome Project all genes (coding DNA sequences) are known. However, of many, their function, and the role of the gene product has not been determined. An example is X-linked adrenoleukodystrophy, the most frequent peroxisomal disorder. Children are born healthy, but in more than 1 out of 3, demyelination of the brain starts unpredictably and they die in a vegetative state. The gene mutated in most families has been known for 10 years; but the true role of the encoded protein, ALDp, is still speculative; and within the same family, very severe and asymptomatic clinical histories co-exist, unexplained by the mutation.
Author: Heinz Engelhardt
Publisher: Springer Science & Business Media
ISBN: 3642692257
Category : Science
Languages : en
Pages : 468
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Book Description
During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).
