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Author: Samir M. Iqbal
Publisher: Springer Science & Business Media
ISBN: 1441982523
Category : Technology & Engineering
Languages : en
Pages : 377
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Book Description
Nanopores are nanometer scale holes formed naturally by proteins or cells, and can be used for a variety of applications, including sequencing DNA and detecting anthrax. They can be integrated into artificially constructed encapsulated cells of silicon wafers while allowing small molecules like oxygen, glucose and insulin to pass, while keeping out large system molecules. "Nanopores: Sensing and Fundamental Biological Interactions" examines the emerging research directions surrounding nanopores such as genome sequencing and early disease detection using biomarker identification. Covering the applications of nanopores in genetics, proteomics, drug discovery, early disease detection and detection of emerging environmental threats, it is a must-have book for biomedicalengineers and research scientists.
Author: Samir M. Iqbal
Publisher: Springer Science & Business Media
ISBN: 1441982523
Category : Technology & Engineering
Languages : en
Pages : 377
Get Book
Book Description
Nanopores are nanometer scale holes formed naturally by proteins or cells, and can be used for a variety of applications, including sequencing DNA and detecting anthrax. They can be integrated into artificially constructed encapsulated cells of silicon wafers while allowing small molecules like oxygen, glucose and insulin to pass, while keeping out large system molecules. "Nanopores: Sensing and Fundamental Biological Interactions" examines the emerging research directions surrounding nanopores such as genome sequencing and early disease detection using biomarker identification. Covering the applications of nanopores in genetics, proteomics, drug discovery, early disease detection and detection of emerging environmental threats, it is a must-have book for biomedicalengineers and research scientists.
Author: Joshua B. Edel
Publisher: William Andrew
ISBN: 143773474X
Category : Science
Languages : en
Pages : 189
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Book Description
Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics
Author: Jean-Pierre Leburton
Publisher: Springer Nature
ISBN: 3031423364
Category : Technology & Engineering
Languages : en
Pages : 234
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Book Description
This contributed volume provides an overview of the recent advances in solid-state nanopore technology, featuring contributions by leading experts in the field. It discusses several aspects of solid-state nanopores, covering their fabrication as well as multiple biosensing applications. It successfully bridges the gap between various scientific and engineering disciplines and highlights the progress made in this area. This title is a useful tool for acquiring basic knowledge of this field and following recent progress. It is a valuable contribution to the area of nanopore biosensing and is of interest to graduate students, postdocs, or senior researchers working in the fields of physical chemistry, biochemistry, bio- and electrical engineering, and biophysics.
Author: Yutaka Suzuki
Publisher: Springer
ISBN: 9811360375
Category : Medical
Languages : en
Pages : 150
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Book Description
This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform. This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications. This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians.
Author: Mario Tagliazucchi
Publisher: William Andrew
ISBN: 0323413625
Category : Technology & Engineering
Languages : en
Pages : 226
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Book Description
Chemically Modified Nanopores and Nanochannels is devoted to chemically modified nanopores and nanochannels, and covers the fundamentals of transport in chemically modified systems, an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies. The book is designed for materials and biomaterials scientists, biomedical engineers, chemists, and chemical engineers who are interested in designing and utilizing processes to synthesize, modify, characterize, use, and model nanopores. The strong chemical focus of the book differentiates it from other books published on nanopores, which traditionally focus either on physics, biophysics, and nanofabrication (solid-state nanopores) or biophysics and biology (biological ion channels and pores). Explains how the chemical modification of nanopores and nanochannels can be used in filtration, membranes, and sensing Provides advanced coverage of novel synthetic applications Focuses on the latest developments in nanopore and nanochannel engineering Presents an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies
Author: M. Muthukumar
Publisher: CRC Press
ISBN: 1420075179
Category : Science
Languages : en
Pages : 362
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Book Description
Polymer translocation occurs in many biological and biotechnological phenomena where electrically charged polymer molecules move through narrow spaces in crowded environments. Unraveling the rich phenomenology of polymer translocation requires a grasp of modern concepts of polymer physics and polyelectrolyte behavior. Polymer Translocation discusse
Author: Branton Daniel
Publisher: World Scientific
ISBN: 9813270624
Category : Science
Languages : en
Pages : 216
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Book Description
This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
Author: Dongyuan Zhao
Publisher: John Wiley & Sons
ISBN: 3527647899
Category : Science
Languages : en
Pages : 544
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Book Description
Mesoporous materials are a class of molecules with a large and uniform pore size, highly regular nanopores, and a large surface area. This book is devoted to all aspects and types of these materials and describes, in an in-depth and systematic manner, the step-by-step synthesis and its mechanism, as well as the characterization, morphology control, hybridization, and applications, of mesoporous molecular sieves. In so doing, it covers silicates, metal-doped silicates, nonsilicates, and organic-inorganic hybrids. Although the emphasis is on synthesis, the expert authors also discuss characterization and applications, ranging from catalysis and biochemistry to optics and the use of these materials as templates for nanomaterial synthesis. Both the fundamentals and the latest research results are covered, ensuring that this monograph serves as a reference for researchers in and newcomers to the field.
Author: Bert Sakmann
Publisher: Springer Science & Business Media
ISBN: 1461578582
Category : Medical
Languages : en
Pages : 506
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Book Description
Single-channel recording has become a widely used tool for the study of ion permeation mechanisms in biological membranes. Whereas the technique might have been considered an "art" after its introduction in 1976, it developed into a relatively simple method after it became possible to obtain high-resistance (several gigaohm) membrane-pipette seals. In the summer of 1982, a course on the technique was held at the Ettore Majorana Center for Scientific Culture in Erice, Sicily. It brought together people from most of the laboratories involved in patch clamping at that time. During the course, it became apparent that the technique had reached a state of maturity. Repeatedly, the opinion was expressed that a detailed description of all the aspects of the technique including representative examples of results should be available. We therefore asked the course instructors, as well as several other colleagues, to provide chapters on selected topics in order to produce this volume. The different variants of patch clamping were described quite extensively in an article by Hamill, Marty, Neher, Sakmann, and Sigworth (Pflugers Archiv 391:85) in 1981. Rather than repeating this survey in an introductory chapter, we chose to reprint that article in the Appendix of this volume (by permission of Springer-Verlag). The methods section will, therefore, go straight into detailed aspects of the technol ogy.
Author: Henry T. Tuckerman
Publisher: DigiCat
ISBN:
Category : Fiction
Languages : en
Pages : 309
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Book Description
The Collector is a collection of essays by Henry T. Tuckerman. It focuses and provides critiques on different books, papers, photographs, local inns and authors and a few other subjects in daft and humorous manner.
