Author: National Research Council
Publisher: National Academies Press
ISBN: 0309255600
Category : Social Science
Languages : en
Pages : 176
Get Book Here
Book Description
In the early 1990s, the Census Bureau proposed a program of continuous measurement as a possible alternative to the gathering of detailed social, economic, and housing data from a sample of the U.S. population as part of the decennial census. The American Community Survey (ACS) became a reality in 2005, and has included group quarters (GQ)-such places as correctional facilities for adults, student housing, nursing facilities, inpatient hospice facilities, and military barracks-since 2006, primarily to more closely replicate the design and data products of the census long-form sample. The decision to include group quarters in the ACS enables the Census Bureau to provide a comprehensive benchmark of the total U.S. population (not just those living in households). However, the fact that the ACS must rely on a sample of what is a small and very diverse population, combined with limited funding available for survey operations, makes the ACS GQ sampling, data collection, weighting, and estimation procedures more complex and the estimates more susceptible to problems stemming from these limitations. The concerns are magnified in small areas, particularly in terms of detrimental effects on the total population estimates produced for small areas. Small Populations, Large Effects provides an in-depth review of the statistical methodology for measuring the GQ population in the ACS. This report addresses difficulties associated with measuring the GQ population and the rationale for including GQs in the ACS. Considering user needs for ACS data and of operational feasibility and compatibility with the treatment of the household population in the ACS, the report recommends alternatives to the survey design and other methodological features that can make the ACS more useful for users of small-area data.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309255635
Category : Social Science
Languages : en
Pages : 176
Get Book Here
Book Description
In the early 1990s, the Census Bureau proposed a program of continuous measurement as a possible alternative to the gathering of detailed social, economic, and housing data from a sample of the U.S. population as part of the decennial census. The American Community Survey (ACS) became a reality in 2005, and has included group quarters (GQ)-such places as correctional facilities for adults, student housing, nursing facilities, inpatient hospice facilities, and military barracks-since 2006, primarily to more closely replicate the design and data products of the census long-form sample. The decision to include group quarters in the ACS enables the Census Bureau to provide a comprehensive benchmark of the total U.S. population (not just those living in households). However, the fact that the ACS must rely on a sample of what is a small and very diverse population, combined with limited funding available for survey operations, makes the ACS GQ sampling, data collection, weighting, and estimation procedures more complex and the estimates more susceptible to problems stemming from these limitations. The concerns are magnified in small areas, particularly in terms of detrimental effects on the total population estimates produced for small areas. Small Populations, Large Effects provides an in-depth review of the statistical methodology for measuring the GQ population in the ACS. This report addresses difficulties associated with measuring the GQ population and the rationale for including GQs in the ACS. Considering user needs for ACS data and of operational feasibility and compatibility with the treatment of the household population in the ACS, the report recommends alternatives to the survey design and other methodological features that can make the ACS more useful for users of small-area data.
Author: Stanton Braude
Publisher: Princeton University Press
ISBN: 1400835453
Category : Science
Languages : en
Pages : 288
Get Book Here
Book Description
An innovative introduction to ecology and evolution This unique textbook introduces undergraduate students to quantitative models and methods in ecology, behavioral ecology, evolutionary biology, and conservation. It explores the core concepts shared by these related fields using tools and practical skills such as experimental design, generating phylogenies, basic statistical inference, and persuasive grant writing. And contributors use examples from their own cutting-edge research, providing diverse views to engage students and broaden their understanding. This is the only textbook on the subject featuring a collaborative "active learning" approach that emphasizes hands-on learning. Every chapter has exercises that enable students to work directly with the material at their own pace and in small groups. Each problem includes data presented in a rich array of formats, which students use to answer questions that illustrate patterns, principles, and methods. Topics range from Hardy-Weinberg equilibrium and population effective size to optimal foraging and indices of biodiversity. The book also includes a comprehensive glossary. In addition to the editors, the contributors are James Beck, Cawas Behram Engineer, John Gaskin, Luke Harmon, Jon Hess, Jason Kolbe, Kenneth H. Kozak, Robert J. Robertson, Emily Silverman, Beth Sparks-Jackson, and Anton Weisstein. Provides experience with hypothesis testing, experimental design, and scientific reasoning Covers core quantitative models and methods in ecology, behavioral ecology, evolutionary biology, and conservation Turns "discussion sections" into "thinking labs" Professors: A supplementary Instructor's Manual is available for this book. It is restricted to teachers using the text in courses. For information on how to obtain a copy, refer to: http://press.princeton.edu/class_use/solutions.html
Author: Richard Primack
Publisher: Open Book Publishers
ISBN: 1783747536
Category : Nature
Languages : en
Pages : 712
Get Book Here
Book Description
Conservation Biology in Sub-Saharan Africa comprehensively explores the challenges and potential solutions to key conservation issues in Sub-Saharan Africa. Easy to read, this lucid and accessible textbook includes fifteen chapters that cover a full range of conservation topics, including threats to biodiversity, environmental laws, and protected areas management, as well as related topics such as sustainability, poverty, and human-wildlife conflict. This rich resource also includes a background discussion of what conservation biology is, a wide range of theoretical approaches to the subject, and concrete examples of conservation practice in specific African contexts. Strategies are outlined to protect biodiversity whilst promoting economic development in the region. Boxes covering specific themes written by scientists who live and work throughout the region are included in each chapter, together with recommended readings and suggested discussion topics. Each chapter also includes an extensive bibliography. Conservation Biology in Sub-Saharan Africa provides the most up-to-date study in the field. It is an essential resource, available on-line without charge, for undergraduate and graduate students, as well as a handy guide for professionals working to stop the rapid loss of biodiversity in Sub-Saharan Africa and elsewhere.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309476097
Category : Medical
Languages : en
Pages : 151
Get Book Here
Book Description
The increasing diversity of population of the United States presents many challenges to conducting health research that is representative and informative. Dispersion and accessibility issues can increase logistical costs; populations for which it is difficult to obtain adequate sample size are also likely to be expensive to study. Hence, even if it is technically feasible to study a small population, it may not be easy to obtain the funding to do so. In order to address the issues associated with improving health research of small populations, the National Academies of Sciences, Engineering, and Medicine convened a workshop in January 2018. Participants considered ways of addressing the challenges of conducting epidemiological studies or intervention research with small population groups, including alternative study designs, innovative methodologies for data collection, and innovative statistical techniques for analysis.
Author: Panel on Statistical Methods for Measuring the Group Quarters Population in the American Community Survey
Publisher: National Academies Press
ISBN: 9780309387576
Category : Social Science
Languages : en
Pages : 163
Get Book Here
Book Description
In the early 1990s, the Census Bureau proposed a program of continuous measurement as a possible alternative to the gathering of detailed social, economic, and housing data from a sample of the U.S. population as part of the decennial census. The American Community Survey (ACS) became a reality in 2005, and has included group quarters (GQ)-such places as correctional facilities for adults, student housing, nursing facilities, inpatient hospice facilities, and military barracks-since 2006, primarily to more closely replicate the design and data products of the census long-form sample. The decision to include group quarters in the ACS enables the Census Bureau to provide a comprehensive benchmark of the total U.S. population (not just those living in households). However, the fact that the ACS must rely on a sample of what is a small and very diverse population, combined with limited funding available for survey operations, makes the ACS GQ sampling, data collection, weighting, and estimation procedures more complex and the estimates more susceptible to problems stemming from these limitations. The concerns are magnified in small areas, particularly in terms of detrimental effects on the total population estimates produced for small areas. Small Populations, Large Effects provides an in-depth review of the statistical methodology for measuring the GQ population in the ACS. This report addresses difficulties associated with measuring the GQ population and the rationale for including GQs in the ACS. Considering user needs for ACS data and of operational feasibility and compatibility with the treatment of the household population in the ACS, the report recommends alternatives to the survey design and other methodological features that can make the ACS more useful for users of small-area data.
Author: Catherine Feuillet
Publisher: Springer Science & Business Media
ISBN: 0387774890
Category : Science
Languages : en
Pages : 774
Get Book Here
Book Description
Sequencing of the model plant genomes such as those of A. thaliana and rice has revolutionized our understanding of plant biology but it has yet to translate into the improvement of major crop species such as maize, wheat, or barley. Moreover, the comparative genomic studies in cereals that have been performed in the past decade have revealed the limits of conservation between rice and the other cereal genomes. This has necessitated the development of genomic resources and programs for maize, sorghum, wheat, and barley to serve as the foundation for future genome sequencing and the acceleration of genomic based improvement of these critically important crops. Cereals constitute over 50% of total crop production worldwide (http://www.fao.org/) and cereal seeds are one of the most important renewable resources for food, feed, and industrial raw materials. Crop species of the Triticeae tribe that comprise wheat, barley, and rye are essential components of human and domestic animal nutrition. With 17% of all crop area, wheat is the staple food for 40% of the world’s population, while barley ranks fifth in the world production. Their domestication in the Fertile Crescent 10,000 years ago ushered in the beginning of agriculture and signified an important breakthrough in the advancement of civilization. Rye is second after wheat among grains most commonly used in the production of bread and is also very important for mixed animal feeds. It can be cultivated in poor soils and climates that are generally not suitable for other cereals. Extensive genetics and cytogenetics studies performed in the Triticeae species over the last 50 years have led to the characterization of their chromosomal composition and origins and have supported intensive work to create new genetic resources. Cytogenetic studies in wheat have allowed the identification and characterization of the different homoeologous genomes and have demonstrated the utility of studying wheat genome evolution as a model for the analysis of polyploidization, a major force in the evolution of the eukaryotic genomes. Barley with its diploid genome shows high collinearity with the other Triticeae genomes and therefore serves as a good template for supporting genomic analyses in the wheat and rye genomes. The knowledge gained from genetic studies in the Triticeae has also been used to produce Triticale, the first human made hybrid crop that results from a cross between wheat and rye and combines the nutrition quality and productivity of wheat with the ruggedness of rye. Despite the economic importance of the Triticeae species and the need for accelerated crop improvement based on genomics studies, the size (1.7 Gb for the bread wheat genome, i.e., 5x the human genome and 40 times the rice genome), high repeat content (>80%), and complexity (polyploidy in wheat) of their genomes often have been considered too challenging for efficient molecular analysis and genetic improvement in these species. Consequently, Triticeae genomics has lagged behind the genomic advances of other cereal crops for many years. Recently, however, the situation has changed dramatically and robust genomic programs can be established in the Triticeae as a result of the convergence of several technology developments that have led to new, more efficient scientific capabilities and resources such as whole-genome and chromosome-specific BAC libraries, extensive EST collections, transformation systems, wild germplasm and mutant collections, as well as DNA chips. Currently, the Triticeae genomics "toolbox" is comprised of: - 9 publicly available BAC libraries from diploid (5), tetraploid (1) and hexaploid (3) wheat; 3 publicly available BAC libraries from barley and one BAC library from rye; - 3 wheat chromosome specific BAC libraries; - DNA chips including commercially available first generation chips from AFFYMETRIX containing 55’000 wheat and 22,000 barley genes; - A large number of wheat and barley genetic maps that are saturated by a significant number of markers; - The largest plant EST collection with 870’000 wheat ESTs, 440’000 barley ESTs and about 10’000 rye ESTs; - Established protocols for stable transformation by biolistic and agrobacterium as well as a transient expression system using VIGS in wheat and barley; and - Large collections of well characterized cultivated and wild genetic resources. International consortia, such as the International Triticeae Mapping Initiative (ITMI), have advanced synergies in the Triticeae genetics community in the development of additional mapping populations and markers that have led to a dramatic improvement in the resolution of the genetic maps and the amount of molecular markers in the three species resulting in the accelerated utilization of molecular markers in selection programs. Together, with the development of the genomic resources, the isolation of the first genes of agronomic interest by map-based cloning has been enabled and has proven the feasibility of forging the link between genotype and phenotype in the Triticeae species. Moreover, the first analyses of BAC sequences from wheat and barley have allowed preliminary characterizations of their genome organization and composition as well as the first inter- and intra-specific comparative genomic studies. These later have revealed important evolutionary mechanisms (e.g. unequal crossing over, illegitimate recombination) that have shaped the wheat and barley genomes during their evolution. These breakthroughs have demonstrated the feasibility of developing efficient genomic studies in the Triticeae and have led to the recent establishment of the International Wheat Genome Sequencing Consortium (IWGSC) (http//:www.wheatgenome.org) and the International Barley Sequencing Consortium (www.isbc.org) that aim to sequence, respectively, the hexaploid wheat and barley genomes to accelerate gene discovery and crop improvement in the next decade. Large projects aiming at the establishment of the physical maps as well as a better characterization of their composition and organization through large scale random sequencing projects have been initiated already. Concurrently, a number of projects have been launched to develop high throughput functional genomics in wheat and barley. Transcriptomics, proteomics, and metabolomics analyses of traits of agronomic importance, such as quality, disease resistance, drought, and salt tolerance, are underway in both species. Combined with the development of physical maps, efficient gene isolation will be enabled and improved sequencing technologies and reduced sequencing costs will permit ultimately genome sequencing and access to the entire wheat and barley gene regulatory elements repertoire. Because rye is closely related to wheat and barley in Triticeae evolution, the latest developments in wheat and barley genomics will be of great use for developing rye genomics and for providing tools for rye improvement. Finally, a new model for temperate grasses has emerged in the past year with the development of the genetics and genomics (including a 8x whole genome shotgun sequencing project) of Brachypodium, a member of the Poeae family that is more closely related to the Triticeae than rice and can provide valuable information for supporting Triticeae genomics in the near future. These recent breakthroughs have yet to be reviewed in a single source of literature and current handbooks on wheat, barley, or rye are dedicated mainly to progress in genetics. In "Genetics and Genomics of the Triticeae", we will aim to comprehensively review the recent progress in the development of structural and functional genomics tools in the Triticeae species and review the understanding of wheat, barley, and rye biology that has resulted from these new resources as well as to illuminate how this new found knowledge can be applied for the improvement of these essential species. The book will be the seventh volume in the ambitious series of books, Plant Genetics and Genomics (Richard A. Jorgensen, series editor) that will attempt to bring the field up-to-date on the genetics and genomics of important crop plants and genetic models. It is our hope that the publication will be a useful and timely tool for researchers and students alike working with the Triticeae.
Author: Giovanni Boniolo
Publisher: Routledge
ISBN: 1317378342
Category : Philosophy
Languages : en
Pages : 224
Get Book Here
Book Description
Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.
Author: Philip W. Hedrick
Publisher: Jones & Bartlett Learning
ISBN: 9780763747725
Category : Medical
Languages : en
Pages : 768
Get Book Here
Book Description
Genetics and Evolution
Author: Michael R. Lynch
Publisher: Oxford University Press
ISBN: 0192663038
Category : Science
Languages : en
Pages : 705
Get Book Here
Book Description
The fields of molecular evolution, genome evolution, and evolutionary genetics are now well-established. Remarkably, however, although all evolutionary modifications begin at the cellular level, and despite the advances made in cell biology and microbiology over the past few decades, there is as yet no recognised discipline of evolutionary cell biology. The goal of this book is to help establish the foundations for this emerging field. Its principal aims are twofold: firstly, to promote an understanding among evolutionary biologists as to why the cellular details matter if we are to understand the mechanisms of evolution; secondly, to make clear to non-evolutionary biologists - cell biologists in particular - that evolution is not just a matter of natural selection and optimization, but a process whose reach depends on other population genetic features such as mutation, recombination, and random genetic drift. Although there are many excellent books on cell biology, microbiology, and biophysics, almost no attention is given to evolution. Likewise, although there are numerous evolutionary biology books on the market, none of them gives more than passing attention to details at the cellular level. Thus Evolutionary Cell Biology is genuinely novel, offering a broader understanding of evolutionary processes and an appreciation for the many interesting problems that remain to be solved at the cellular and subcellular levels. This advanced textbook is aimed at both cell biologists and evolutionary biologists. It will be accessible to upper-level undergraduates in biology, and certainly to graduate students in all areas of the life sciences. Professionals from a wide range of fields - cell biology, microbiology, evolution, biophysics, biochemistry, and mathematics - will be exposed to entirely new ideas not traditionally covered in their primary fields of expertise.
