Author: Lee B. Reichman
Publisher:
ISBN:
Category : Tuberculosis
Languages : en
Pages : 792
Book Description
Tuberculosis
Author: Lee B. Reichman
Publisher:
ISBN:
Category : Tuberculosis
Languages : en
Pages : 792
Book Description
Publisher:
ISBN:
Category : Tuberculosis
Languages : en
Pages : 792
Book Description
Tuberculosis Drug Discovery and Development 2019
Author: Giovanna Riccardi
Publisher: MDPI
ISBN: 3039432362
Category : Science
Languages : en
Pages : 296
Book Description
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.
Publisher: MDPI
ISBN: 3039432362
Category : Science
Languages : en
Pages : 296
Book Description
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and still represents one of the global health threats to mankind. The World Health Organization estimated more than 10 million new cases and reported more than 1.5 million deaths in 2019, thus ranking TB among the main causes of death due to a single pathogen. Standard anti-TB therapy includes four first-line antibiotics that should be administered for at least six months. However, in the case of multi- and extensively drug-resistant TB, second-line medications must be used and these frequently cause severe side effects resulting in poor compliance. Developing new anti-TB drug candidates is therefore of outmost importance. In this Special Issue dedicated to Tuberculosis Drug Discovery and Development, we present the main and latest achievements in the fields of drug and target discovery, host-directed therapy, anti-virulence drugs, and describe the development of two advanced compounds: macozinone and delpazolid. In addition, this Special Issue provides an historical perspective focused on Carlo Forlanini, the inventor of pneumothorax for TB treatment, and includes an overview of the state-of-the-art technologies which are being exploited nowadays in TB drug development. Finally, a summary of TB vaccines that are either approved or undergoing clinical trials concludes the Special Issue.
Pearson's Thoracic & Esophageal Surgery
Author: G. Alexander Patterson
Publisher: Churchill Livingstone
ISBN: 9780443068911
Category : Chest
Languages : en
Pages : 0
Book Description
Published as two individual books in its previous editions, this acclaimed reference now comes to you as one comprehensive two-volume resource, covering the entire range of esophageal and thoracic surgery for adults and children. Sixty nine brand-new chapters and 92 new authors deliver state-of-the-art, clear how-to-do-it guidance on the latest surgical techniques for the treatment of lung infections, lung cancer, benign conditions, trauma, reflux, and more-so you can effectively manage every common and uncommon condition you encounter. A new full-color design presents outstanding visual guidance that shows you exactly how to proceed, and a logical organization throughout makes reference easy. As an Expert Consult title, this thoroughly updated 3rd edition comes with access to the complete contents online, fully searchable-enabling you to consult it rapidly from any computer with an Internet connection. Addresses all surgical diseases of the chest wall, chest cavity, upper airway, lungs, pleura, and diaphragm in adults and children, giving you the comprehensive coverage you need for the patients you see. Presents clinical commentary at the end of each chapter that offers you a variety of viewpoints regarding the pros, cons, and complications associated with the techniques used to treat a patient.
Publisher: Churchill Livingstone
ISBN: 9780443068911
Category : Chest
Languages : en
Pages : 0
Book Description
Published as two individual books in its previous editions, this acclaimed reference now comes to you as one comprehensive two-volume resource, covering the entire range of esophageal and thoracic surgery for adults and children. Sixty nine brand-new chapters and 92 new authors deliver state-of-the-art, clear how-to-do-it guidance on the latest surgical techniques for the treatment of lung infections, lung cancer, benign conditions, trauma, reflux, and more-so you can effectively manage every common and uncommon condition you encounter. A new full-color design presents outstanding visual guidance that shows you exactly how to proceed, and a logical organization throughout makes reference easy. As an Expert Consult title, this thoroughly updated 3rd edition comes with access to the complete contents online, fully searchable-enabling you to consult it rapidly from any computer with an Internet connection. Addresses all surgical diseases of the chest wall, chest cavity, upper airway, lungs, pleura, and diaphragm in adults and children, giving you the comprehensive coverage you need for the patients you see. Presents clinical commentary at the end of each chapter that offers you a variety of viewpoints regarding the pros, cons, and complications associated with the techniques used to treat a patient.
Tuberculosis
Author: M. Monir Madkour
Publisher: Springer Science & Business Media
ISBN: 3642189377
Category : Medical
Languages : en
Pages : 974
Book Description
A comprehensive textbook on tuberculosis that covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. The main part of the book comprises very detailed and richly illustrated clinical chapters. The copious images are the advantage of this book. Chapters on new methods and treatments and on animal tuberculosis are included. The material is based on a wealth of experience in tuberculosis as seen in endemic countries such as Saudi Arabia that enjoy free access to advanced investigative and therapeutic facilities. This coexistence of endemicity of the disease and state-of-the-art facilities is rare in poor and developing countries or in rich and developed nations. This multidisciplinary volume is ideal for all clinicians, laboratory and research workers, epidemiologists, university teachers and students, health care planners and international organizations involved in world health and infectious disease.
Publisher: Springer Science & Business Media
ISBN: 3642189377
Category : Medical
Languages : en
Pages : 974
Book Description
A comprehensive textbook on tuberculosis that covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. The main part of the book comprises very detailed and richly illustrated clinical chapters. The copious images are the advantage of this book. Chapters on new methods and treatments and on animal tuberculosis are included. The material is based on a wealth of experience in tuberculosis as seen in endemic countries such as Saudi Arabia that enjoy free access to advanced investigative and therapeutic facilities. This coexistence of endemicity of the disease and state-of-the-art facilities is rare in poor and developing countries or in rich and developed nations. This multidisciplinary volume is ideal for all clinicians, laboratory and research workers, epidemiologists, university teachers and students, health care planners and international organizations involved in world health and infectious disease.
Medical Management of the Thoracic Surgery Patient E-Book
Author: Michael I. Lewis
Publisher: Elsevier Health Sciences
ISBN: 1437711073
Category : Medical
Languages : en
Pages : 687
Book Description
Medical Management of the Thoracic Surgery Patient, by Michael I. Lewis, MD and Robert J. McKenna, Jr., MD, is a comprehensive pulmonary and thoracic reference that takes a practical approach to the diagnosis, workup and care of the thoracic surgery patient. It is geared towards pulmonary and critical care physicians and their trainees as well as all other specialties with whom thoracic surgeons consult and interact. It outlines the principles for understanding the underlying disease entities as well as the clinical implications and complications of surgery, and interprets key surgical concepts such as correlative and functional anatomy for non-surgeons. Contributions from today’s authorities...“at-a-glance detailed key information, as well as summary bullets...and a multidisciplinary perspective, combine to offer essential guidance for confident patient management. As an Expert Consult title it includes convenient online access to the complete contents of the book—fully searchable—along with video clips of thoracic procedures, patient information sheets, all of the images downloadable for your personal use, and references linked to Medline at www.expertconsult.com. Includes access to a companion website at expertconsult.com where you can search the complete contents of the book, watch video clips of thoracic procedures, print out patient information sheets, download all of the images, and review references linked to Medline...providing you with a powerful resource for convenient consultation anytime, anywhere. Features ‘real world’ illustrative cases presented in a brief, bulleted format that facilitates easy access to and retention of the material. Examines every aspect of diagnosis and management for pre-, peri-, and postoperative care for an all-encompassing reference to respond to unique surgical problems. Provides coverage of individual topics supplemented by a brief case-based presentation, where appropriate, that lend a real-life perspective to the material. Contains all of the “need-to-know facts for a complete, thorough consultation in diagnosis and treatment of patients who undergo thoracic surgery. Offers practical information that utilizes the experience of today’s leaders while based on evidence in the literature for coverage you can trust. Examines current clinical controversies, providing you with an arena for discussion of sensitive topics and guidance on preferred approaches when relevant. Presents pearls, pitfalls, key points, and other learning elements in each chapter, to help you locate summaries of essential information “at-a-glance. Features chapters written by specialists of various disciplines, to equip you with a balanced perspective on each condition.
Publisher: Elsevier Health Sciences
ISBN: 1437711073
Category : Medical
Languages : en
Pages : 687
Book Description
Medical Management of the Thoracic Surgery Patient, by Michael I. Lewis, MD and Robert J. McKenna, Jr., MD, is a comprehensive pulmonary and thoracic reference that takes a practical approach to the diagnosis, workup and care of the thoracic surgery patient. It is geared towards pulmonary and critical care physicians and their trainees as well as all other specialties with whom thoracic surgeons consult and interact. It outlines the principles for understanding the underlying disease entities as well as the clinical implications and complications of surgery, and interprets key surgical concepts such as correlative and functional anatomy for non-surgeons. Contributions from today’s authorities...“at-a-glance detailed key information, as well as summary bullets...and a multidisciplinary perspective, combine to offer essential guidance for confident patient management. As an Expert Consult title it includes convenient online access to the complete contents of the book—fully searchable—along with video clips of thoracic procedures, patient information sheets, all of the images downloadable for your personal use, and references linked to Medline at www.expertconsult.com. Includes access to a companion website at expertconsult.com where you can search the complete contents of the book, watch video clips of thoracic procedures, print out patient information sheets, download all of the images, and review references linked to Medline...providing you with a powerful resource for convenient consultation anytime, anywhere. Features ‘real world’ illustrative cases presented in a brief, bulleted format that facilitates easy access to and retention of the material. Examines every aspect of diagnosis and management for pre-, peri-, and postoperative care for an all-encompassing reference to respond to unique surgical problems. Provides coverage of individual topics supplemented by a brief case-based presentation, where appropriate, that lend a real-life perspective to the material. Contains all of the “need-to-know facts for a complete, thorough consultation in diagnosis and treatment of patients who undergo thoracic surgery. Offers practical information that utilizes the experience of today’s leaders while based on evidence in the literature for coverage you can trust. Examines current clinical controversies, providing you with an arena for discussion of sensitive topics and guidance on preferred approaches when relevant. Presents pearls, pitfalls, key points, and other learning elements in each chapter, to help you locate summaries of essential information “at-a-glance. Features chapters written by specialists of various disciplines, to equip you with a balanced perspective on each condition.
Oxford Handbook of Respiratory Medicine
Author: Stephen Chapman
Publisher: OUP Oxford
ISBN: 0191054569
Category : Medical
Languages : en
Pages : 933
Book Description
Revised and updated for its third edition, the Oxford Handbook of Respiratory Medicine is the must-have resource for junior doctors and students, and all clinicians caring for patients with respiratory problems. Concise, practical, and designed for rapid access to essential information, this handbook will ensure you have everything you need for the ward, clinic, or exams. This handbook covers the latest clinical guidelines and developments in the field. It features unique sections on practical procedures and a symptoms section to aid in differential diagnosis and clinical management. Practical advice on management is integrated throughout and a dedicated section on respiratory emergencies ensures you can cope with any eventuality. New sections such as thoracic ultrasound, indwelling pleural catheters, safe sedation, and cardiopulmonary exercise testing have been added, and all major respiratory diseases and symptoms are covered in practical, succinct chapters. This third edition will ensure you have all the information you need at your fingertips.
Publisher: OUP Oxford
ISBN: 0191054569
Category : Medical
Languages : en
Pages : 933
Book Description
Revised and updated for its third edition, the Oxford Handbook of Respiratory Medicine is the must-have resource for junior doctors and students, and all clinicians caring for patients with respiratory problems. Concise, practical, and designed for rapid access to essential information, this handbook will ensure you have everything you need for the ward, clinic, or exams. This handbook covers the latest clinical guidelines and developments in the field. It features unique sections on practical procedures and a symptoms section to aid in differential diagnosis and clinical management. Practical advice on management is integrated throughout and a dedicated section on respiratory emergencies ensures you can cope with any eventuality. New sections such as thoracic ultrasound, indwelling pleural catheters, safe sedation, and cardiopulmonary exercise testing have been added, and all major respiratory diseases and symptoms are covered in practical, succinct chapters. This third edition will ensure you have all the information you need at your fingertips.
Practical Thoracoscopy
Author: Christian Boutin
Publisher: Springer Science & Business Media
ISBN: 3642755585
Category : Medical
Languages : en
Pages : 109
Book Description
Diseases of the pleura such as effusion, thickening, or pneumothorax are frequently encountered in the practice of medicine. Practical Thoracoscopy presents an encyclopedic approach to the use of thoracoscopy in the diag nosis and treatment of patients with pleural disease. After an initial chapter on the history of thoracoscopy, the next three chapters of the book are devoted to the general technique of performing thoracoscopy, a topic on which the team of Dr. Boutin and his colleagues write with ample experience. In these chapters they provide detailed de scriptions of how to perform the procedure and discuss the pros and the cons of the different approaches and the different equipment available. The following chapter discusses the complications of the procedure. The next chapter discusses the role of thoracoscopy in diagnosing pleu ral effusions. My own opinion here is in general that, as long as well trained personnel are available, thoracoscopy is preferable to open pleural biopsy, because it is associated with less morbidity and mortality and can be done if necessary under local anesthesia. The following chapter is directed at using to thoracoscopy to facilitate pleurodesis for chronic pleural effusions. With Boutin's method, talc pou drage is performed during thoracoscopy, and certainly, if a thoracoscopy is used to establish the diagnosis of a malignant pleural effusion, it is appro priate to attempt to induce a pleurodesis with talc at the time of the diag nostic procedure.
Publisher: Springer Science & Business Media
ISBN: 3642755585
Category : Medical
Languages : en
Pages : 109
Book Description
Diseases of the pleura such as effusion, thickening, or pneumothorax are frequently encountered in the practice of medicine. Practical Thoracoscopy presents an encyclopedic approach to the use of thoracoscopy in the diag nosis and treatment of patients with pleural disease. After an initial chapter on the history of thoracoscopy, the next three chapters of the book are devoted to the general technique of performing thoracoscopy, a topic on which the team of Dr. Boutin and his colleagues write with ample experience. In these chapters they provide detailed de scriptions of how to perform the procedure and discuss the pros and the cons of the different approaches and the different equipment available. The following chapter discusses the complications of the procedure. The next chapter discusses the role of thoracoscopy in diagnosing pleu ral effusions. My own opinion here is in general that, as long as well trained personnel are available, thoracoscopy is preferable to open pleural biopsy, because it is associated with less morbidity and mortality and can be done if necessary under local anesthesia. The following chapter is directed at using to thoracoscopy to facilitate pleurodesis for chronic pleural effusions. With Boutin's method, talc pou drage is performed during thoracoscopy, and certainly, if a thoracoscopy is used to establish the diagnosis of a malignant pleural effusion, it is appro priate to attempt to induce a pleurodesis with talc at the time of the diag nostic procedure.
Pocket Book of Hospital Care for Children
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241548371
Category : Business & Economics
Languages : en
Pages : 442
Book Description
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Publisher: World Health Organization
ISBN: 9241548371
Category : Business & Economics
Languages : en
Pages : 442
Book Description
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Tuberculosis in Adults and Children
Author: Dorothee Heemskerk
Publisher: Springer
ISBN: 3319191322
Category : Medical
Languages : en
Pages : 71
Book Description
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Publisher: Springer
ISBN: 3319191322
Category : Medical
Languages : en
Pages : 71
Book Description
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Disease Control Priorities, Third Edition (Volume 6)
Author: King K. Holmes
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 1027
Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 1027
Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.