Author: Alexandra P. Marques
Publisher: Academic Press
ISBN: 0128110007
Category : Science
Languages : en
Pages : 474
Book Description
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. - Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more - Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models - Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing - Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Skin Tissue Models
Author: Alexandra P. Marques
Publisher: Academic Press
ISBN: 0128110007
Category : Science
Languages : en
Pages : 474
Book Description
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. - Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more - Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models - Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing - Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Publisher: Academic Press
ISBN: 0128110007
Category : Science
Languages : en
Pages : 474
Book Description
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. - Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more - Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models - Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing - Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Three Dimensional Human Organotypic Models for Biomedical Research
Author: Fabio Bagnoli
Publisher: Springer Nature
ISBN: 3030624528
Category : Medical
Languages : en
Pages : 265
Book Description
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Publisher: Springer Nature
ISBN: 3030624528
Category : Medical
Languages : en
Pages : 265
Book Description
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
Dermatokinetics of Therapeutic Agents
Author: S. Narasimha Murthy
Publisher: CRC Press
ISBN: 1439804788
Category : Medical
Languages : en
Pages : 216
Book Description
Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.Presenting the first compre
Publisher: CRC Press
ISBN: 1439804788
Category : Medical
Languages : en
Pages : 216
Book Description
Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.Presenting the first compre
Organotypic Models in Drug Development
Author: Monika Schäfer-Korting
Publisher: Springer Nature
ISBN: 3030700631
Category : Medical
Languages : en
Pages : 325
Book Description
This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
Publisher: Springer Nature
ISBN: 3030700631
Category : Medical
Languages : en
Pages : 325
Book Description
This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
Physiologically Based Pharmacokinetic Modeling
Author: Micaela Reddy
Publisher: John Wiley & Sons
ISBN: 0471478776
Category : Science
Languages : en
Pages : 420
Book Description
A definitive, single source of information on PBPK modeling Physiologically-based pharmacokinetic (PBPK) modeling is becomingincreasingly important in human health risk assessments and insupporting pharmacodynamic modeling for toxic responses. Organizedby classes of compounds and modeling purposes so users can quicklyaccess information, this is the first comprehensive reference ofits kind. This book presents an overview of the underlying principles of PBPKmodel development. Then it provides a compendium of PBPK modelinginformation, including historical development, specific modelingchallenges, and current practices for: * Halogenated Alkanes * Halogenated Alkenes * Alkene and Aromatic Compounds * Reactive Vapors in the Nasal Cavity * Alkanes, Oxyhydrocarbons, and Related Compounds * Pesticides and Persistent Organic Pollutants * Dioxin and Related Compounds * Metals and Inorganic Compounds * Drugs * Antineoplastic Agents * Perinatal Transfer * Mixtures * Dermal Exposure Models In addition to pinpointing specific information, readers canexplore diverse modeling techniques and applications. Anauthoritative reference for toxicologists, ecotoxicologists, riskassessors, regulators, pharmacologists, pharmacists, and graduatestudents in pharmacokinetics and toxicology, Physiologically-BasedPharmacokinetic Modeling compiles information from leaders in thefield and discusses future directions for PBPK modeling.
Publisher: John Wiley & Sons
ISBN: 0471478776
Category : Science
Languages : en
Pages : 420
Book Description
A definitive, single source of information on PBPK modeling Physiologically-based pharmacokinetic (PBPK) modeling is becomingincreasingly important in human health risk assessments and insupporting pharmacodynamic modeling for toxic responses. Organizedby classes of compounds and modeling purposes so users can quicklyaccess information, this is the first comprehensive reference ofits kind. This book presents an overview of the underlying principles of PBPKmodel development. Then it provides a compendium of PBPK modelinginformation, including historical development, specific modelingchallenges, and current practices for: * Halogenated Alkanes * Halogenated Alkenes * Alkene and Aromatic Compounds * Reactive Vapors in the Nasal Cavity * Alkanes, Oxyhydrocarbons, and Related Compounds * Pesticides and Persistent Organic Pollutants * Dioxin and Related Compounds * Metals and Inorganic Compounds * Drugs * Antineoplastic Agents * Perinatal Transfer * Mixtures * Dermal Exposure Models In addition to pinpointing specific information, readers canexplore diverse modeling techniques and applications. Anauthoritative reference for toxicologists, ecotoxicologists, riskassessors, regulators, pharmacologists, pharmacists, and graduatestudents in pharmacokinetics and toxicology, Physiologically-BasedPharmacokinetic Modeling compiles information from leaders in thefield and discusses future directions for PBPK modeling.
Handbook of Cosmetic Science and Technology
Author: Frank Dreher
Publisher: CRC Press
ISBN: 1000590607
Category : Medical
Languages : en
Pages : 451
Book Description
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice
Publisher: CRC Press
ISBN: 1000590607
Category : Medical
Languages : en
Pages : 451
Book Description
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice
Comprehensive Biomaterials II
Author: Kevin Healy
Publisher: Elsevier
ISBN: 0081006926
Category : Technology & Engineering
Languages : en
Pages : 4865
Book Description
Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Publisher: Elsevier
ISBN: 0081006926
Category : Technology & Engineering
Languages : en
Pages : 4865
Book Description
Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Handbook of Cosmetic Science and Technology
Author: André O. Barel
Publisher: CRC Press
ISBN: 1420069683
Category : Medical
Languages : en
Pages : 890
Book Description
Edited by a team of experienced and internationally renowned contributors, the updated Third Edition is the standard reference for cosmetic chemists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for skin, hair, and nails.New features in the Third Editi
Publisher: CRC Press
ISBN: 1420069683
Category : Medical
Languages : en
Pages : 890
Book Description
Edited by a team of experienced and internationally renowned contributors, the updated Third Edition is the standard reference for cosmetic chemists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for skin, hair, and nails.New features in the Third Editi
Tissue Engineering
Author: Clemens van Blitterswijk
Publisher: Academic Press
ISBN: 0323851347
Category : Science
Languages : en
Pages : 800
Book Description
Tissue Engineering, Third Edition provides a completely revised release with sections focusing on Fundamentals of Tissue Engineering and Tissue Engineering of Selected Organs and Tissues. Key chapters are updated with the latest discoveries, including coverage of new areas (skeletal TE, ophthalmology TE, immunomodulatory biomaterials and immune systems engineering). The book is written in a scientific language that is easily understood by undergraduate and graduate students in basic biological sciences, bioengineering and basic medical sciences, and researchers interested in learning about this fast-growing field. - Presents a clear structure of chapters that is aimed at those new to the field - Includes new chapters on immune systems engineering, skeletal tissue engineering (skeletal muscle, tendon, and ligament) eye, cornea and ophthalmology tissue engineering - Includes applied clinical cases studies that illustrate basic science applications
Publisher: Academic Press
ISBN: 0323851347
Category : Science
Languages : en
Pages : 800
Book Description
Tissue Engineering, Third Edition provides a completely revised release with sections focusing on Fundamentals of Tissue Engineering and Tissue Engineering of Selected Organs and Tissues. Key chapters are updated with the latest discoveries, including coverage of new areas (skeletal TE, ophthalmology TE, immunomodulatory biomaterials and immune systems engineering). The book is written in a scientific language that is easily understood by undergraduate and graduate students in basic biological sciences, bioengineering and basic medical sciences, and researchers interested in learning about this fast-growing field. - Presents a clear structure of chapters that is aimed at those new to the field - Includes new chapters on immune systems engineering, skeletal tissue engineering (skeletal muscle, tendon, and ligament) eye, cornea and ophthalmology tissue engineering - Includes applied clinical cases studies that illustrate basic science applications
AI 2005: Advances in Artificial Intelligence
Author: Shichao Zhang
Publisher: Springer
ISBN: 3540316523
Category : Computers
Languages : en
Pages : 1369
Book Description
The 18th Australian Joint Conference on Artificial Intelligence (AI 2005) was held at the University of Technology, Sydney (UTS), Sydney, Australia from 5 to 9 December 2005. AI 2005 attracted a historical record number of submissions, a total of 535 papers. The review process was extremely selective. Out of these 535 submissions, the Program Chairs selected only 77 (14.4%) full papers and 119 (22.2%) short papers based on the review reports, making an acceptance rate of 36.6% in total. Authors of the accepted papers came from over 20 countries. This volume of the proceedings contains the abstracts of three keynote speeches and all the full and short papers. The full papers were categorized into three broad sections, namely: AI foundations and technologies, computational intelligence, and AI in specialized domains. AI 2005 also hosted several tutorials and workshops, providing an interacting mode for specialists and scholars from Australia and other countries. Ronald R. Yager, Geoff Webb and David Goldberg (in conjunction with ACAL05) were the distinguished researchers invited to give presentations. Their contributions to AI 2005 are really appreciated.
Publisher: Springer
ISBN: 3540316523
Category : Computers
Languages : en
Pages : 1369
Book Description
The 18th Australian Joint Conference on Artificial Intelligence (AI 2005) was held at the University of Technology, Sydney (UTS), Sydney, Australia from 5 to 9 December 2005. AI 2005 attracted a historical record number of submissions, a total of 535 papers. The review process was extremely selective. Out of these 535 submissions, the Program Chairs selected only 77 (14.4%) full papers and 119 (22.2%) short papers based on the review reports, making an acceptance rate of 36.6% in total. Authors of the accepted papers came from over 20 countries. This volume of the proceedings contains the abstracts of three keynote speeches and all the full and short papers. The full papers were categorized into three broad sections, namely: AI foundations and technologies, computational intelligence, and AI in specialized domains. AI 2005 also hosted several tutorials and workshops, providing an interacting mode for specialists and scholars from Australia and other countries. Ronald R. Yager, Geoff Webb and David Goldberg (in conjunction with ACAL05) were the distinguished researchers invited to give presentations. Their contributions to AI 2005 are really appreciated.