Drug-Drug Interactions for Therapeutic Biologics

Drug-Drug Interactions for Therapeutic Biologics PDF Author: Honghui Zhou
Publisher: John Wiley & Sons
ISBN: 1118630211
Category : Medical
Languages : en
Pages : 272

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Book Description
Strategize, plan, and execute comprehensive drug-drug interaction assessments for therapeutic biologics Offering both theory and practical guidance, this book fully explores drug-drug interaction assessments for therapeutic biologics during the drug development process. It draws together and analyzes all the latest findings and practices in order to present our current understanding of the topic and point the way to new research. Case studies and examples, coupled with expert advice, enable readers to better understand the complex mechanisms of biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics features contributions from leading international experts in all areas of therapeutic biologics drug development and drug-drug interactions. The authors' contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small molecules and other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment and prediction Risk-based strategies for evaluating biologic drug-drug interactions Strategies to minimize drug-drug interaction risk and mitigate toxic interactions Key regulations governing drug-drug interaction assessments for therapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics is recommended for pharmaceutical and biotechnology scientists, clinical pharmacologists, medicinal chemists, and toxicologists. By enabling these readers to understand how therapeutic biologics may interact with other drugs, the book will help them develop safer, more effective therapeutic biologics.

Drug-Drug Interactions for Therapeutic Biologics

Drug-Drug Interactions for Therapeutic Biologics PDF Author: Honghui Zhou
Publisher: John Wiley & Sons
ISBN: 1118630211
Category : Medical
Languages : en
Pages : 272

Get Book

Book Description
Strategize, plan, and execute comprehensive drug-drug interaction assessments for therapeutic biologics Offering both theory and practical guidance, this book fully explores drug-drug interaction assessments for therapeutic biologics during the drug development process. It draws together and analyzes all the latest findings and practices in order to present our current understanding of the topic and point the way to new research. Case studies and examples, coupled with expert advice, enable readers to better understand the complex mechanisms of biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics features contributions from leading international experts in all areas of therapeutic biologics drug development and drug-drug interactions. The authors' contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small molecules and other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment and prediction Risk-based strategies for evaluating biologic drug-drug interactions Strategies to minimize drug-drug interaction risk and mitigate toxic interactions Key regulations governing drug-drug interaction assessments for therapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics is recommended for pharmaceutical and biotechnology scientists, clinical pharmacologists, medicinal chemists, and toxicologists. By enabling these readers to understand how therapeutic biologics may interact with other drugs, the book will help them develop safer, more effective therapeutic biologics.

Diabetes and Hypertension

Diabetes and Hypertension PDF Author: Samy I. McFarlane
Publisher: Springer Science & Business Media
ISBN: 1603273573
Category : Medical
Languages : en
Pages : 196

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Book Description
Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.

Sir Philip Sidney's Arcadia

Sir Philip Sidney's Arcadia PDF Author: Sir Philip Sidney
Publisher:
ISBN:
Category : English fiction
Languages : en
Pages : 536

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Book Description


Holstein-Friesian Herd-book

Holstein-Friesian Herd-book PDF Author: Holstein-Friesian Association of America
Publisher:
ISBN:
Category : Cattle
Languages : en
Pages : 764

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Book Description


The countesse of Pembrokes Arcadia

The countesse of Pembrokes Arcadia PDF Author: Philip Sidney
Publisher:
ISBN:
Category :
Languages : en
Pages : 588

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Book Description


52 Years Living With Diabetes

52 Years Living With Diabetes PDF Author: James Zajac
Publisher: Dorrance Publishing
ISBN: 1434915131
Category : Health & Fitness
Languages : en
Pages : 122

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Book Description
52 Years Living with Diabetes: In Spite of the Medical Profession by James Zajac In 52 Years Living with Diabetes: In Spite of the Medical Profession, author James Zajac details the arduous road from his diagnosis with diabetes at age thirteen to his current successful-albeit untraditional-management of the disease at age sixty-five. Zajac describes the genesis of his diabetes following a childhood bout with rheumatic fever, shortly after which he first got a taste of the negligence and indifference rampant in the medical community, engendering an early distrust in traditional medicine. He then recounts his youthful rebellion against the management of his disease, until a chance meeting with a forward-thinking doctor set him on a path of self-sufficiency that persists to this day. Throughout, Zajac provides invaluable advice regarding natural, non-traditional diabetes treatments, while exposing the incompetence of the medical professionals he has encountered through the years. Zajac concludes the book by challenging the state of healthcare in the United States, providing statistical as well as anecdotal information that calls for reform at the very root of the system. 52 Years is an enlightening window into the life of a diabetic and his lifelong mission to encourage the American public to take their healthcare into their own hands. About the Author A Connecticut native, James Zajac has lived in Pennsylvania for over forty years. He lives with his wife and enjoys gardening, bike riding, swimming, horseback riding, kayaking, and skiing.

Continuous Glucose Monitoring

Continuous Glucose Monitoring PDF Author: Weiping Jia
Publisher: Springer
ISBN: 9811070741
Category : Medical
Languages : en
Pages : 215

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Book Description
This book provides comprehensive information on continuous glucose monitoring (CGM). The first section focuses on the fundamentals of CGM technology, including the principles of CGM, accuracy assessment, operation procedure, management processes, the picture-interpretation methodology, the clinical value of CGM parameters, reference values, clinical applications of CGM report and management systems, and clinical indications. In turn, the second section describes the clinical application of CGM, including assessing blood glucose fluctuation and hypoglycemic effects, detecting hypoglycemia and identifying fasting hyperglycemia. It also describes the role of CGM in connection with specific diseases, such as fulminant type 1 diabetes, gestational diabetes mellitus, steroid diabetes, and insulinoma. The closing chapter outlines the future of CGM. In addition, the book presents typical cases and analyses of nearly a hundred typical monitoring maps. As such, it offers diabetic health care doctors a valuable reference guide to the clinical application of and scientific research on CGM.

Pharmacy Calculations

Pharmacy Calculations PDF Author: Matthew Rewald
Publisher:
ISBN: 9781585286386
Category : Medical
Languages : en
Pages : 0

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Book Description
Offering a complete review of the basic mathematics concepts and skills, Pharmacy Calculations: An Introduction for Pharmacy Technicians, Second Edition provides students with the pharmacy basics necessary for correctly interpreting prescriptions and drug orders, and for performing dosing calculations that technicians face every day. The second edition has been streamlined to focus on the most important pharmacy calculation concepts-covering the fundamentals related to accuracy and basic math operations, units of measurement and conversions, critical thinking in problem solving, dosing calculations, percentages, concentration calculations, compounding formulas, intravenous infusion calculations, and business math. What's new in this edition? The chapters are broken down into four units and organized to complement most pharmacy technician training curricula and to support the ASHP-ACPE model curriculum: Review of Mathematics Systems of Measurement Preparing for Problem Solving in Pharmacy Dosing Calculations and other Pharmacy Problems Key features throughout the book include: Chapter objectives Key terms and definitions Examples of problem scenarios or calculations questions and solutions "Tech Note!" - provides a highlight of key points within the chapters "Numbers at Work" - illustrates why key concepts are important to know and skills are critical to master Practice problems Appendices that include the parts of a prescription, a glossary of terms, conversions, and abbreviations tables

Polycystic Ovary Syndrome

Polycystic Ovary Syndrome PDF Author: Andrea Dunaif
Publisher: Springer Science & Business Media
ISBN: 1597451088
Category : Medical
Languages : en
Pages : 361

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Book Description
This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Diabetes? Insulin-Dependent?...

Diabetes? Insulin-Dependent?... PDF Author: Professor Kinga Howorka M.D.
Publisher: Xlibris Corporation
ISBN: 1456816136
Category : Medical
Languages : en
Pages : 203

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Book Description
Insulin-dependent?... In addition to the introduction to Functional Insulin Treatment for physicians (K. Howorka, Springer Publishers Berlin), this book presents guidelines for people with diabetes to treat their condition using Functional Insulin Treatment. Only after meticulous reading of this manual does it become clear, how many already well-known facts and other things that have never been heard of before, have been put here together in a methodological whole. Contradictions that you may have experienced personally suddenly become strikingly clear in this context. After a short self-testing period with FIT, the fear of completely inexplicable blips in your blood glucose is overcome, and you can feel selfassured, since you know the causes and provide solutions. FIT is the most modern and effective method to facilitate the control of insulin requiring diabetes. With FIT, sometimes you do not even have to know the basics on how to multiply. Philosophies and esoteric recommendations are replaced by a couple of numbers with which you can calculate. Although the problems remain the same, FIT offers you an intelligent and practical possibility of solving them by summarizing all of the treatment possibilities available today. W.D., after 48 years with diabetes DiabetesFIT is a registered trademark for Functional Insulin Treatment, related media and education. ...only with Dr. Howorkas FIT therapy I was able to ascend the Mount Everest, the highest mountain of the world and to fulfill the dream of my life... Geri Winkler. Extreme sportsman and teacher with diabetes, http://www.winklerworld.net