Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings PDF Author: Arjen M. Dondorp
Publisher: Springer
ISBN: 3030031438
Category : Medical
Languages : en
Pages : 226

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Book Description
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings PDF Author: Arjen M. Dondorp
Publisher: Springer
ISBN: 3030031438
Category : Medical
Languages : en
Pages : 226

Get Book Here

Book Description
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Sepsis Management

Sepsis Management PDF Author: Jordi Rello
Publisher: Springer Science & Business Media
ISBN: 3642035191
Category : Medical
Languages : en
Pages : 243

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Book Description
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Sepsis

Sepsis PDF Author: Nicholas S. Ward
Publisher: Humana Press
ISBN: 3319484702
Category : Medical
Languages : en
Pages : 271

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Book Description
This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.​

Early-onset Neonatal Sepsis

Early-onset Neonatal Sepsis PDF Author: Karen D. Fairchild
Publisher:
ISBN: 9781437718553
Category : Neonatology
Languages : en
Pages : 0

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Book Description


Handbook of Sepsis

Handbook of Sepsis PDF Author: W. Joost Wiersinga
Publisher: Springer
ISBN: 3319735063
Category : Medical
Languages : en
Pages : 264

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Book Description
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

New Strategies for Treatment of Sepsis

New Strategies for Treatment of Sepsis PDF Author: Antonio Mirijello
Publisher: Mdpi AG
ISBN: 9783036524832
Category : Medical
Languages : en
Pages : 146

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Book Description
This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

Hemodynamic Monitoring

Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer
ISBN: 3319692690
Category : Medical
Languages : en
Pages : 476

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Book Description
This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Sepsis

Sepsis PDF Author: Nancy Khardori
Publisher: Nova Science Publishers
ISBN: 9781631172441
Category : Septicemia
Languages : en
Pages : 0

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Book Description
The book discusses multiple aspects of sepsis syndrome seen in all age groups of patients and by all specialties in medicine. The syndrome is the aftermath of the dissemination of an infectious process into and through the blood stream. This allows the bacteria, bacterial products and cytokines to reach multiple organs, resulting in their dysfunction. In spite of the advances in supportive care and antibiotic therapy, the outcome of sepsis has not changed significantly. The inadequacies in the current diagnostic modalities and conflicting inconclusive results of investigations on novel treatments have contributed significantly to the lack of progress in the management of sepsis. Antibiotic overuse in and outside the intensive care unit driven by the lack of microbiological data and definitive diagnosis lends to the creation and transmission of antibiotic resistant bacteria, which has added to the challenges and poor outcomes of sepsis syndrome. The nine chapters in this book are authored by experts in various aspects of sepsis from North America, South America, Europe and Asia. State of the art information is provided in the areas of pathogenesis, epidemiology, diagnosis and management of sepsis. Each chapter has a contribution on the role of various evidence-based preventive strategies to reduce the incidence and subsequent poor outcomes of sepsis syndrome.

Oxford Handbook of Critical Care Nursing

Oxford Handbook of Critical Care Nursing PDF Author: Fiona Creed
Publisher: Oxford University Press
ISBN: 0191059331
Category : Medical
Languages : en
Pages : 417

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Book Description
Focused on the practical issues of nursing care and nursing procedures, the Oxford Handbook of Critical Care Nursing has been written by nurses, for nurses Reflecting current best practice, this handbook is an easily accessible and evidence-based guide for all levels of nursing staff working in critical care environments. It provides the nurse at the bedside with the answers to day-to-day problems experienced when caring for critically ill patients, and is also a guide to some of the less commonly encountered issues. Now including more detail on the psychological issues facing critically ill patients and further information on the intricacies of receiving and transferring critically ill patients to and from critical care environments, this handbook is a concise, practical, evidence-based guide for nursing professionals caring for critically ill patients

The Sepsis Text

The Sepsis Text PDF Author: Jean-Louis Vincent
Publisher: Springer Science & Business Media
ISBN: 0306476649
Category : Medical
Languages : en
Pages : 848

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Book Description
This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.