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Author: Thomas L. Schwartz
Publisher: AuthorHouse
ISBN: 1524619736
Category : Medical
Languages : en
Pages : 100
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Book Description
The second generation antipsychotics are a complex class of psychiatric medications, applicable to a diverse range of both FDA approved treatment indications and off-label uses. This variety stems largely from the unique pharmacodynamic profile of each agent, and often necessitates the employment of unique dosing strategies across the treatment of the varied psychiatry disorders, including schizophrenia, bipolar mania and depression, major depressive disorder, and autism. Despite the shared mechanism of dopamine D2 and serotonin-2a dual receptor blockade, which mediates the antipsychotic and antimanic properties of the second generation antipsychotics, the unique pharmacodynamic signature of each agent is subsequently responsible for the additional and varied antidepressant, anxiolytic, hypnotic, and tolerability profile observed with each drug. Using an evidence based approach, this comprehensive handbook aims to highlight and discuss data relevant to treatment indications, off-labels uses, and dosing strategies of the 11 currently FDA approved second generation antipsychotics, with a strong emphasis on the pharmacodynamic profiles of these drugs. With the advent of three relatively new antipsychotics (lurasidone in 2011, brexpiprazole in 2015, and cariprazine in 2015), this text will serve as an excellent reference for practicing physicians, research investigators, and medical students alike. This review addresses not only these clinical applications, but provides physicians with the tools necessary to optimize treatment based upon patient diagnosis, proper antipsychotic selection, and implementation of an appropriate dosing strategy, thereby striking an essential balance between treatment efficacy and patient tolerability.
Author: Thomas L. Schwartz
Publisher: AuthorHouse
ISBN: 1524619736
Category : Medical
Languages : en
Pages : 100
Get Book Here
Book Description
The second generation antipsychotics are a complex class of psychiatric medications, applicable to a diverse range of both FDA approved treatment indications and off-label uses. This variety stems largely from the unique pharmacodynamic profile of each agent, and often necessitates the employment of unique dosing strategies across the treatment of the varied psychiatry disorders, including schizophrenia, bipolar mania and depression, major depressive disorder, and autism. Despite the shared mechanism of dopamine D2 and serotonin-2a dual receptor blockade, which mediates the antipsychotic and antimanic properties of the second generation antipsychotics, the unique pharmacodynamic signature of each agent is subsequently responsible for the additional and varied antidepressant, anxiolytic, hypnotic, and tolerability profile observed with each drug. Using an evidence based approach, this comprehensive handbook aims to highlight and discuss data relevant to treatment indications, off-labels uses, and dosing strategies of the 11 currently FDA approved second generation antipsychotics, with a strong emphasis on the pharmacodynamic profiles of these drugs. With the advent of three relatively new antipsychotics (lurasidone in 2011, brexpiprazole in 2015, and cariprazine in 2015), this text will serve as an excellent reference for practicing physicians, research investigators, and medical students alike. This review addresses not only these clinical applications, but provides physicians with the tools necessary to optimize treatment based upon patient diagnosis, proper antipsychotic selection, and implementation of an appropriate dosing strategy, thereby striking an essential balance between treatment efficacy and patient tolerability.
Author: Ian Stolerman
Publisher: Springer Science & Business Media
ISBN: 3540686983
Category : Medical
Languages : en
Pages : 1433
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Book Description
Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.
Author: Peter Haddad
Publisher: Oxford University Press
ISBN: 0191045780
Category : Medical
Languages : en
Pages : 266
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Book Description
Antipsychotic Long-acting Injections (LAIs) were introduced in the 1960s to improve treatment adherence in schizophrenia. Subsequently, first-generation antipsychotic LAIs became widely used in many countries. Since the initial publication of Antipsychotic Long-acting Injections in 2010, new trial data have been published on long-acting injection (LAI) preparations of the drugs Risperidone, Paliperidone, and Olanzapine. Furthermore, a new LAI preparation of the drug Aripiprazole has recently been approved for clinical use in the United States and is likely to be approved in Europe soon. The second edition of this successful book has been fully updated to include this new data, with reference to both observational studies and randomized controlled trials, as well as other new developments in the clinical use of antipsychotic LAIs. New chapters have been added covering the comparison between oral and injectable antipsychotics, Olanzapine LAI, Aripiprazole LAI, and the practicalities of organizing a specialized clinic for long-acting injectable antipsychotics. Existing chapters have also been thoroughly updated to take into account the most recently published research. Antipsychotic Long-acting Injections, Second edition brings together clinical and research findings on LAIs in a comprehensive volume, with chapters written by international experts.
Author: Samar Reghunandanan
Publisher: OUP Oxford
ISBN: 019101687X
Category : Medical
Languages : en
Pages : 167
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Book Description
Providing clinicians and patients with the latest developments in research, this new edition is a succinct and practical introduction to the diagnosis, evaluation and management of OCD and other related disorders. Part of the Oxford Psychiatry Library series, this pocketbook includes individual chapters on the phenomenology, pathogenesis, pharmacotherapy and psychotherapy of OCD and other related disorders, and features fully updated content and research. The book also includes a helpful resources chapter, and an Appendix with summaries of the major rating scales used to assess patients with OCD, which will be of use to both clinicians and patients. Obsessive-compulsive disorder (OCD) and Obsessive-compulsive-related disorders (OCRDs) are anxiety disorders characterized by obsessions and compulsions, and varying degrees of anxiety and depression. OCRDs are considered to be one of the most disabling of psychiatric disorders and they present a tremendous economic and social burden, both for the affected individual, their family, and for society at large. In contrast to other psychiatric conditions of a comparable or lesser prevalence and patient burden, relatively little is understood about the aetiology, and cognitive effects of OCRDs.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547693
Category : Medical
Languages : en
Pages : 80
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Book Description
This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Author: Lieuwe De Haan
Publisher: Springer
ISBN: 331912952X
Category : Medical
Languages : en
Pages : 220
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Book Description
This book summarizes scientific advances in our understanding of the interrelationship between obsessive-compulsive symptoms and schizophrenia and reflects on the implications for future research directions. In addition, guidelines are provided on practical assessment, diagnosis and treatment interventions, covering both pharmacotherapy and psychotherapy. The book acknowledges the need for a perspective that recognizes heterogeneous subgroups and diverse neurobiological explanations; accordingly, multidimensional research-based conceptual frameworks are provided that incorporate recent epidemiological, neurocognitive, neurogenetic and pharmacodynamic findings. Obsessive-Compulsive Symptoms in Schizophrenia has been written by an international team of experts who offer insights gained through their extensive experience. It will be an invaluable guide to this frequent and clinically important comorbidity and will be particularly useful for mental health practitioners.
Author: Stephen M. Stahl
Publisher: Cambridge University Press
ISBN: 1108446566
Category : Medical
Languages : en
Pages : 525
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Book Description
Presents a user-friendly step-by-step manual on the psychotropic drugs prescribed for children and adolescents by clinicians and nurse practitioners.
Author: Katherine J. Aitchison
Publisher: CRC Press
ISBN: 9781853174353
Category : Medical
Languages : en
Pages : 152
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Book Description
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.
Author: Thomas L. Schwartz
Publisher: Nova Science Publishers
ISBN: 9781621000716
Category : Antipsychotic drugs
Languages : en
Pages : 0
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Book Description
Since the mid-1990s, a revolution in regards to prescribing antipsychotics has taken place. Once utilized only for schizophrenia, the newer, second generation antipsychotics have now been approved for the treatment of bipolar disorders, depressive disorders, and autism spectrum disorders. They are often utilised elsewhere for the treatment of anxiety disorders, sleep disorders, and to calm agitated patients when dangerous behaviours occur. Prescription rates have soared making them some of the most advertised, prescribed and profitable drugs on the market. This book was developed with input of international authors of varying backgrounds to review the history and development of these agents and to focus on the utilization of these drugs in various disorders, age groups, and clinical situations.
Author: S. Nassir Ghaemi
Publisher: Oxford University Press
ISBN: 0199995508
Category : Medical
Languages : en
Pages : 601
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Book Description
Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.
