Risk Factors for Prostate Cancer in African Veterans PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Risk Factors for Prostate Cancer in African Veterans PDF full book. Access full book title Risk Factors for Prostate Cancer in African Veterans by . Download full books in PDF and EPUB format.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
The feasibility of developing a veteran cohort to evaluate factors that influence prostate cancer incidence was assessed. We identified 80,720 eligible veterans without prostate cancer through VA computerized records for six Medical Centers (VAMC) . A lifestyle questionnaire was mailed along with a dietary survey (HFFQ) to 3,000 veterans (500 per site), randomly selected from a file of eligible participants. A phone survey was developed to ascertain reasons for non-response from individuals who didn't participate after two mailing attempts. The response rate overall was 24.4% Response was lower for African-Americans (19.4%) than Whites (29.4%). Veterans were also recruited through a face-to-face approach at one VAMC. Of 121 eligible veterans, 90% agreed to participate and were handed or mailed surveys to return to us. The overall return rate was 42.6%. Response among Whites was higher (60.0%) than African-Americans (32.4%). Most veterans contacted regarding non-response felt the survey asked too many questions. African-American non-responders were more concerned about confidentiality and reported more difficulties understanding questions. Though survey response was not as high as expected, the VA provides a unique arena to establish observational cohorts for assessing the health of African-American and White men.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
The feasibility of developing a veteran cohort to evaluate factors that influence prostate cancer incidence was assessed. We identified 80,720 eligible veterans without prostate cancer through VA computerized records for six Medical Centers (VAMC) . A lifestyle questionnaire was mailed along with a dietary survey (HFFQ) to 3,000 veterans (500 per site), randomly selected from a file of eligible participants. A phone survey was developed to ascertain reasons for non-response from individuals who didn't participate after two mailing attempts. The response rate overall was 24.4% Response was lower for African-Americans (19.4%) than Whites (29.4%). Veterans were also recruited through a face-to-face approach at one VAMC. Of 121 eligible veterans, 90% agreed to participate and were handed or mailed surveys to return to us. The overall return rate was 42.6%. Response among Whites was higher (60.0%) than African-Americans (32.4%). Most veterans contacted regarding non-response felt the survey asked too many questions. African-American non-responders were more concerned about confidentiality and reported more difficulties understanding questions. Though survey response was not as high as expected, the VA provides a unique arena to establish observational cohorts for assessing the health of African-American and White men.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 63
Get Book Here
Book Description
The feasibility of developing a cohort of veterans to evaluate risk factors that influence prostate cancer incidence is being assessed. On-site investigators are being established at six VA Medical Centers (VAMC) across the country to obtain local IRB approval and to establish blood drawing facilities for willing participants. Through VA computerized patient records, we have identified 121,781 veterans without prostate cancer that are eligible for recruitment at the six VAMCs. Mailing addresses are being obtained from the VA National Computer Center and from local sites. A short and long version of a lifestyle survey has been developed to capture information on demographics, medical history, physical health, smoking, etc.. This will be sent with a dietary survey (HFFQ) to 3,000 veterans (500 per site), randomly selected from our master file of eligible participants.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 10
Get Book Here
Book Description
Prostate cancer is the most common cancer among US men, yet the etiology of this disease remains unclear. This study used military health care and demographic data to describe the incidence of prostate cancer in the US military from September 1993 to September 2003, and to identify demographic and occupational risk factors for prostate cancer hospitalization. Annual rates of first-encounter prostate cancer were adjusted for age and race. Cox's proportional hazards regression was employed to model the time to prostate cancer diagnosis. This study supports previous observations of an increased prostate cancer risk among black non-Hispanic men. Further, this study illustrated that this association exists regardless of access to care or socioeconomic status, which has not previously been reported in the literature. This finding suggests that black, non-Hispanic men may share yet-to-be-explored differences that may be important in prostate cancer etiology.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 33
Get Book Here
Book Description
African American men are at greater risk for developing and dying from prostate cancer compared to white men. This disparity is likely due to a number of factors including environmental and genetic factors. The Flint Men's Health Study (FMHS) was established in 1995 as a population-based case-control study of African American men aged 40-79 residing in Genesee County, Michigan. The initial sample consisted of 730 men who completed an in-home interview consisting of potential risk factors for prostate cancer; medical history; and demographic data. 431 men provided a blood sample and 369 men who were determined to be free of cancer completed a comprehensive urologic exam. Additionally, 119 cases of prostate cancer have been identified from the same population. Studies have suggested a role for hormones and genetics in cancer incidence. However, studies have been completed in white populations and results have been conflicting. The objective of this study is to more clearly delineate the potential role(s) of selected hormones and growth factors in prostate cancer development.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
A study was funded by the US Army Medical Research and Material Command titled, "Comorbidities and Health Outcomes of African American Men with Prostate Cancer: An Analysis of Outpatient and Hospital Discharge Data." The primary data source that was used for this study is the SEER-HCFA Linked Data Set for African Americans with Prostate Cancer. These data contain encounters for the years 1995 and 1996 for all Medicare patients with prostate cancer including charges and payments made by the Medicare program. However, as a result of the delays in obtaining this complex data set, we have chosen to develop a baseline analysis over an eighteen year period using the National Hospital Discharge Survey Multi-Year Data File, 1979-1997. This data set will focus on all US inpatients with prostate cancer, those having radical prostatectomies, and most importantly, the characteristics and trends for this disease and procedure for African Americans. Patients were identified from the years 1979 through 1997 who matched the principle diagnosis of prostate cancer (ICD-9-CM=185). In addition, we identified those diseases that simultaneously existed with the admission of the patient identified as comorbidities along with those diagnoses that occurred intra-operatively and postoperatively. The goal of the study was to measure the eighteen year trends of demographics of patients with prostate cancer, radical prostatectomies and most importantly, the risk factors attributable to African Americans.
Author: Andrew W. Bruce
Publisher: Springer Science & Business Media
ISBN: 1447113985
Category : Medical
Languages : en
Pages : 363
Get Book Here
Book Description
Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 15
Get Book Here
Book Description
Several lines of evidence have suggested genetic and dietary differences may be important in PCa, particularly among AA (African American) men. In this study, we aimed to test the hypothesis that mutations/sequence variants in the AMACR gene, and dietary intake of foods rich in phytanic acid, increase the risk to PCa among AA men. We conducted a population based study by ascertaining 213 AA men who have PCa and 264 race, age, and county-matched controls from 15 counties of North Carolina. We have completed the 1st task, study subject recruitment. We have also obtained additional grant funding related to the science of this project, which will help provide independent confirmation of the findings from this study in a different study population. We have used the newly recruited study population to complete a study confirming genome-wide variants in AA PCa cases and controls, and our results are in-press. The results from this project have increased our knowledge of potential risk factors and suggest potential preventive strategies for prostate cancer in AA men.
Author:
Publisher: Office of the Surgeon General
ISBN:
Category : Health & Fitness
Languages : en
Pages : 80
Get Book Here
Book Description
Promotes the recognition, treatment, and prevention of conditions of overweight and obesity in the United States.
Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides
Publisher: National Academies Press
ISBN: 9780309075299
Category : Medical
Languages : en
Pages : 791
Get Book Here
Book Description
Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309075521
Category : Medical
Languages : en
Pages : 623
Get Book Here
Book Description
Veterans and Agent Orange: Update 2000 examines the state of the scientific evidence regarding associations between diseases and exposure to dioxin and other chemical compounds in herbicides used in Vietnam. It is the fourth in a series of comprehensive reviews of epidemiologic and toxicologic studies of the agents used as defoliants during the Vietnam War. Over forty health outcomes in veterans and their children are addressed. Among the report's conclusions is that there is sufficient evidence of a link between exposure and the development of soft-tissue sarcoma, non-Hodgkin's lymphoma, Hodgkin's disease, and chloracne in veterans. Additionally, it found that scientific studies offer "limited or suggestive" evidence of an association with other diseases in veteransâ€"including Type 2 diabetes, respiratory cancers, prostate cancer, multiple myeloma and some forms of transient peripheral neuropathyâ€"as well as the congenital birth defect spina bifida in veterans' children.
