Report of the Workshop on the Feasibility of a Chronic Neurotoxicity Study of Aluminum Administered in the Drinking Water of Animals PDF Download
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Author: Canada. Health Canada
Publisher:
ISBN:
Category :
Languages : en
Pages : 63
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Book Description
Author: Canada. Health Canada
Publisher:
ISBN:
Category :
Languages : en
Pages : 63
Get Book Here
Book Description
Author: Canada. Health Canada
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Summarizes proceedings and discussions, and includes contributed papers, from a workshop held to investigate the feasibility of a study of the chronic neurotoxicity of aluminium administered in drinking water of animals. Such a study could be used to establish a health-based guideline for human exposure to aluminium in drinking water. The papers addressed the following issues: problems involved in the assessment of the human health effects of aluminium in drinking water; the importance of aluminium speciation and substances that affect speciation; the appropriateness of an animal study in human risk assessment; the best animal model and the appropriate end-points to be measured; aluminium absorption, accumulation site and pathway, and effects of age on accumulation of aluminium in animals; and methods for avoiding contamination from aluminium during an animal study.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309076293
Category : Nature
Languages : en
Pages : 242
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Book Description
Having safe drinking water is important to all Americans. The Environmental Protection Agency's decision in the summer of 2001 to delay implementing a new, more stringent standard for the maximum allowable level for arsenic in drinking water generated a great deal of criticism and controversy. Ultimately at issue were newer data on arsenic beyond those that had been examined in a 1999 National Research Council report. EPA asked the National Research Council for an evaluation of the new data available. The committee's analyses and conclusions are presented in Arsenic in Drinking Water: 2001 Update. New epidemiological studies are critically evaluated, as are new experimental data that provide information on how and at what level arsenic in drinking water can lead to cancer. The report's findings are consistent with those of the 1999 report that found high risks of cancer at the previous federal standard of 50 parts per billion. In fact, the new report concludes that men and women who consume water containing 3 parts per billion of arsenic daily have about a 1 in 1,000 increased risk of developing bladder or lung cancer during their lifetime.
Author: Qiao Niu
Publisher: Springer
ISBN: 9811313709
Category : Medical
Languages : en
Pages : 191
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Book Description
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
Author:
Publisher:
ISBN: 9781904384106
Category : Animal experimentation
Languages : en
Pages : 335
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Book Description
A report of the Nuffield Council on Bioethics working party investigating the ethical issues of research involving animals.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030910128X
Category : Nature
Languages : en
Pages : 531
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Book Description
Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.
Author:
Publisher:
ISBN: 9780660460239
Category : Drinking water
Languages : en
Pages : 0
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Book Description
"Malathion is a registered insecticide and acaricide used on a wide variety of sites including agricultural and non-agricultural sites. In 2018 (the most recent year for which data are available), over 25 000 kg of malathion was sold in Canada. Malathion may be released into surface water or soil as runoff from the application site. Malathion is not usually found in drinking water sources in Canada. Low levels of malathion have been found in several Canadian provinces. The maximum reported concentrations are well below the MAC. Malathion is rarely detected in foods"--Executive summary.
Author: Christian Kazner
Publisher: IWA Publishing
ISBN: 1843392755
Category : Science
Languages : en
Pages : 481
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Book Description
The best papers from the three-day conference on Safe Drinking Water from Source to Tap June 2009 in Maastricht are published in this book covering the themes of challenges of the water sector and adaptive strategies, treatment, distribution, risk assessment and risk management, sensors and monitoring, small scale systems, simulation, alternative water supply & sources, consumer involvement, and future drinking water. Worldwide, the water supply sector is facing tremendous challenges. Every new emerging contaminants and pathogens and aging infrastructures that are vulnerable for deliberate contamination pose a threat to the quality of water supplies. Shortage of good quality and readily treatable resources is increasing due to global warming, urbanisation and pollution from agriculture and industry. Regulators and consumers are becoming more demanding. Techneau - the largest European project on drinking water - addresses these challenges by developing adaptive supply system options and new and improved treatment and monitoring technologies. Future system options to be studied are flexible, small scale and multi-source supplies, utilising non conventional resources like brackish ground water, treated wastewater and urban groundwater.
Author: Allan Astrup Jensen
Publisher:
ISBN:
Category : Business & Economics
Languages : en
Pages : 132
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Book Description
Life Cycle Assessment
Author: Committee on Curriculum Development in Environmental Medicine
Publisher: National Academies Press
ISBN: 0309568722
Category : Medical
Languages : en
Pages : 988
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Book Description
People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.
