Reconstituted Sendai Virus Envelopes as Intra-articular Drug Vectors PDF Download
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Author: Rupert T. Earl
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Rupert T. Earl
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: R. T. Earl
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1332
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Author: Jean R. Philippot
Publisher: CRC Press
ISBN: 1351360868
Category : Science
Languages : en
Pages : 481
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Book Description
This book is devoted to a broader understanding of liposomes as a versatile tool used in many domains, including basic research and applied technology, focusing on less common applications and recent developments. Over the past few years, new types of liposomes made of nonphospholipid molecules have opened new perspectives in applications. These lipid vesicles, already used in cosmetology, are being manufactured for industrial and agricultural uses. However, "Stealth" liposomes, pH-sensitive liposomes, and cationic liposomes have enlarged and improved the application field of liposomes in clinical research. The book covers these different uses of liposomes with particular attention to new formulations and new applications.
Author: Israel Hanin
Publisher: Springer Science & Business Media
ISBN: 1475791453
Category : Medical
Languages : en
Pages : 690
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Book Description
This book represents the third in a series of International Conferences related to Alzheimer's (AD) and Parkinson's (PD) diseases. The first one took place in Eilat, Israel, in 1985; and the second one in Kyoto, Japan, in 1989. This book contains the full text of oral and poster presentations from the Third International Conference on Alzheimer's and Parkinson's Diseases: Recent Developments, held in Chicago, Illinois, U.S.A. on November 1-6, 1993. The Chicago Conference was attended by 270 participants. The Scientific Program was divided into nine oral sessions, a keynote presentation, and a poster session. The conference culminated in a Round Table Discussion involving all of the participants in the conference. The four and one-half day meeting served as an excellent medium for surveying the current status of clinical and preclinical developments in AD and PD. There were 59 oral presentations and 93 posters. This book incorporates a majority of both.
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Category : AIDS (Disease)
Languages : en
Pages : 508
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Author: Shmuel Razin
Publisher: Springer Science & Business Media
ISBN: 0306476061
Category : Science
Languages : en
Pages : 574
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Book Description
was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.
Author: Leslie J. Fairbairn
Publisher: Springer Science & Business Media
ISBN: 1461548896
Category : Medical
Languages : en
Pages : 402
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Book Description
Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency (ADA-SCID) were transplanted with T-cells express ing adenosine deaminase (the defective enzyme in patients with this disorder). The partial success of this treatment was perhaps responsible for undue optimism among those proposing other gene therapy treatments within the hematopoietic system, and it has since become clear that there are a number of technical and biological difficulties to overcome before hematopoietic gene therapy becomes a mainstream therapeutic strategy. The chapters in this book evaluate the need for gene therapy in the hematopoietic system, discuss how efficient gene transfer and expression can be achieved in the target cells, highlight areas of difficulty to be addressed, and examine a number of potential applications of the gene therapy approach. The book begins with a chapter by Testa and colleagues, discussing the various sources of hematopoietic cells for both transplantation and gene therapy.
Author: Otto-Wilhelm Merten
Publisher: Humana
ISBN: 9781617790942
Category : Medical
Languages : en
Pages : 0
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Book Description
The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of gene products. While thoroughly covering the most popular viral vector systems of adenovirus, retrovirus, and adeno-associated virus, this detailed volume also explores less common viral vector systems such as baculovirus, herpes virus, and measles virus, the growing interest in which is creating a considerable demand for large scale manufacturing and purification procedures. Written in the highly successful Methods in Molecular BiologyTM series format, many chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Viral Vectors for Gene Therapy: Methods and Protocols provides basic principles accessible to scientists from a wide variety of backgrounds for the development of gene therapy viral products that are safe and effective.
Author: Gregory I. Bain
Publisher: Springer
ISBN: 3662457199
Category : Medical
Languages : en
Pages : 410
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Book Description
This cutting-edge monograph on advanced clinical anatomy and pathoanatomy of the shoulder, written by the world’s leading authors, reflects recent significant advances in understanding of anatomy and pathology. It is beautifully illustrated with exquisite photographs of anatomical specimens, and images from arthroscopy, histology, and radiology complete the picture. The accompanying text brings out the clinical, biomechanical, and functional relevance and focuses on aspects important to the high-performance athlete. In addition, the book closely assesses how each component of the normal anatomy responds to trauma, disease, and degeneration. The finer points of the pathoanatomy are demonstrated with clinical cases, histology, radiology, arthroscopy, and open surgery. The text details how the pathoanatomy affects the patient presentation, clinical examination, and imaging. It is also explained how the pathology affects the natural history and the outcome of physical therapy and influences recommendations for surgical treatments. This book will be of immense value both to trainees and to specialists who manage disorders of the shoulder, including orthopedic surgeons, sports physicians, and physiotherapists. It will also be of great interest to anatomists and pathologists.
