Receptor Data for Biological Experiments PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Receptor Data for Biological Experiments PDF full book. Access full book title Receptor Data for Biological Experiments by Henri N. Doods. Download full books in PDF and EPUB format.
Author: Henri N. Doods
Publisher: Taylor & Francis Group
ISBN:
Category : Medical
Languages : en
Pages : 300
Get Book
Book Description
Provides comprehensive coverage of the most relevant knowledge on classification, localization and biological effects of receptor systems and/or enzymes.
Author: Henri N. Doods
Publisher: Taylor & Francis Group
ISBN:
Category : Medical
Languages : en
Pages : 300
Get Book
Book Description
Provides comprehensive coverage of the most relevant knowledge on classification, localization and biological effects of receptor systems and/or enzymes.
Author: Van Meels Doods
Publisher:
ISBN: 9780745808567
Category :
Languages : en
Pages : 120
Get Book
Book Description
Author: Douglas A. Lauffenburger
Publisher: Oxford University Press
ISBN: 0190283068
Category : Science
Languages : en
Pages : 376
Get Book
Book Description
Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.
Author: Lee E. Limbird
Publisher: Springer Science & Business Media
ISBN: 0387230807
Category : Medical
Languages : en
Pages : 226
Get Book
Book Description
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest. The study of receptors has changed considerably over the period of the publication of the three editions of this book. The cloning of several genomes makes it unlikely that preparations of receptors now or in the future will arise from their purification as trace proteins from native tissues, but rather from a myriad of molecular approaches. Nonetheless, understanding the molecular mechanisms and ultimately the in vivo biology of these receptors means that investigators will engage in molecular, cellular and ultimate in vivo strategies. It should be of value to investigators who want to identify, characterize and understand the biology of a receptor of interest.
Author: Povl Krogsgaard-Larsen
Publisher: Taylor & Francis
ISBN: 9780132967167
Category : Medical
Languages : en
Pages : 404
Get Book
Book Description
Designed to reflect the growing awareness of the chemical aspects of excitatory amino acids, this text uses computer-based methods and X-ray techniques to depict and analyze molecules and structure-activity relationships. The book incorporates stereochemical principles into all analyses.
Author: Jonathan W. Boyd
Publisher: John Wiley & Sons
ISBN: 1119060265
Category : Science
Languages : en
Pages : 336
Get Book
Book Description
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 1483259706
Category : Science
Languages : en
Pages : 457
Get Book
Book Description
Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.
Author: Anthony P. Davenport
Publisher: Humana
ISBN: 9781588294203
Category : Medical
Languages : en
Pages : 240
Get Book
Book Description
A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.
Author: Raimund J. Ober
Publisher: CRC Press
ISBN: 0429892128
Category : Medical
Languages : en
Pages : 693
Get Book
Book Description
Quantitative bioimaging is a broad interdisciplinary field that exploits tools from biology, chemistry, optics, and statistical data analysis for the design and implementation of investigations of biological processes. Instead of adopting the traditional approach of focusing on just one of the component disciplines, this textbook provides a unique introduction to quantitative bioimaging that presents all of the disciplines in an integrated manner. The wide range of topics covered include basic concepts in molecular and cellular biology, relevant aspects of antibody technology, instrumentation and experimental design in fluorescence microscopy, introductory geometrical optics and diffraction theory, and parameter estimation and information theory for the analysis of stochastic data. Key Features: Comprises four parts, the first of which provides an overview of the topics that are developed from fundamental principles to more advanced levels in the other parts. Presents in the second part an in-depth introduction to the relevant background in molecular and cellular biology and in physical chemistry, which should be particularly useful for students without a formal background in these subjects. Provides in the third part a detailed treatment of microscopy techniques and optics, again starting from basic principles. Introduces in the fourth part modern statistical approaches to the determination of parameters of interest from microscopy data, in particular data generated by single molecule microscopy experiments. Uses two topics related to protein trafficking (transferrin trafficking and FcRn-mediated antibody trafficking) throughout the text to motivate and illustrate microscopy techniques. An online appendix providing the background and derivations for various mathematical results presented or used in the text is available at http://www.routledge.com/9781138598980.
Author: Mostafa Z. Badr
Publisher:
ISBN: 9781493991952
Category : Ligands
Languages : en
Pages : 314
Get Book
Book Description
This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering our understanding of these vital receptors and their role in numerous pathological conditions.
