The T Cell Receptor FactsBook PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The T Cell Receptor FactsBook PDF full book. Access full book title The T Cell Receptor FactsBook by Marie-Paule Lefranc. Download full books in PDF and EPUB format.
Author: Marie-Paule Lefranc
Publisher: Elsevier
ISBN: 0080542646
Category : Medical
Languages : en
Pages : 413
Get Book Here
Book Description
The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.
Author: Marie-Paule Lefranc
Publisher: Elsevier
ISBN: 0080542646
Category : Medical
Languages : en
Pages : 413
Get Book Here
Book Description
The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.
Author: Krishna C. Persaud
Publisher: CRC Press
ISBN: 1439871728
Category : Medical
Languages : en
Pages : 237
Get Book Here
Book Description
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author: Alan Glynn
Publisher:
ISBN: 9780571316267
Category :
Languages : en
Pages : 320
Get Book Here
Book Description
1950s Manhattan: the CIA carries out a covert study of psychoactive drugs. Ad man Ned Sweeney is dosed with MDT-48, and finds his horizons dramatically expand. But how long can he maintain the extraordinary pace of his new life? Sixty years later, all that Ray Sweeney knows of his grandfather's life is that he committed suicide. But then Ray meets a retired government official, who claims he can illuminate the truth behind Ned's death. Both a sequel and a prequel to The Dark Fields, which was adapted into the hit movie Limitless, Under the Night explores the seductive power and dangers of unlocking the human mind.
Author: Richard M. Restak
Publisher: Bantam
ISBN:
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
And he takes us into the laboratories of today's molecular chemists and neuroscientists who are creating drugs that will change our brains in ways that only a few years ago seemed the stuff of science fiction.
Author: John C. Foreman
Publisher: CRC Press
ISBN: 1420052551
Category : Medical
Languages : en
Pages : 314
Get Book Here
Book Description
For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from this course, the perennially bestselling Textbook of Receptor Pharmacology has presented in-depth coverage of this rapidly expanding area of research. This third edition continues to combine current understanding of classica
Author: Anthony P. Davenport
Publisher: Humana
ISBN: 9781588294203
Category : Medical
Languages : en
Pages : 240
Get Book Here
Book Description
A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.
Author: Mostafa Z. Badr
Publisher: Springer Nature
ISBN: 3030783154
Category : Medical
Languages : en
Pages : 676
Get Book Here
Book Description
Nuclear receptors are ligand activated transcription factors that control numerous biological functions. Consequently, altering activity of these receptors is proposed, and indeed documented, to affect many physiological and pathological conditions in experimental animals and humans. Thus, nuclear receptors have become a major target in the effort to treat numerous diseases. This book will shed light on and emphasize intricate processes involved in designing as well as discovering physiological and pharmacological modulators of these important proteins. World-renowned scientists will share with the reader their professional expertise and extensive experience acquired through decades working with nuclear receptors. Chapters address the various means and consequences of modulating nuclear receptor activity will be presented and discussed. These modulators cover a wide span of moieties ranging from synthetic chemicals to natural products. In addition, the classification of these chemicals ranges from pan agonists to selective agonists and inverse agonists to antagonists. They also include proteolytic means to obliterate the receptor in the event that modulating its activity through canonical pharmacological agents becomes less effective and/or less desirable due to anticipated or experienced toxicities. Modulation of receptor activity may also take place in the absence of a ligand or through manipulating the structure of the receptor itself by controlling posttranslational events.
Author: Amitabha Chattopadhyay
Publisher: CRC Press
ISBN: 1420005758
Category : Medical
Languages : en
Pages : 230
Get Book Here
Book Description
A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from l
Author: Vincent Laudet
Publisher: Gulf Professional Publishing
ISBN: 9780124377356
Category : Medical
Languages : en
Pages : 486
Get Book Here
Book Description
The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references
Author: Douglas A. Lauffenburger
Publisher: Oxford University Press
ISBN: 0190283068
Category : Science
Languages : en
Pages : 376
Get Book Here
Book Description
Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.
