Re-Purposing Suzuki

Re-Purposing Suzuki PDF Author: Maria Porter
Publisher: Routledge
ISBN: 1000475840
Category : Performing Arts
Languages : en
Pages : 159

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Book Description
Re-Purposing Suzuki: A Hybrid Approach to Actor Training introduces a system of text analysis that synthesizes physical, psychological, and vocal components in order to truthfully embody heightened texts and contexts. By understanding how the author has re-purposed Suzuki and other physical training methods, as well as Stanislavski, readers will gain an awareness of how to analyze a particular training method by extrapolating its key components and integrating it into a holistic, embodied approach to text analysis. The book explores a method of physical scoring via Rules of the Body and Rules of Composition, as well as a method of approaching heightened texts from Greek drama to post-modern playwrights that draws on the individual actor’s imagination and experience and integrates voice, mind, and body. Readers will be able to either replicate this approach, or apply the logic of its building blocks to assemble their own personal creative process applicable to a variety of performance genres. This is a source book for actors, theatre students, practitioners, and educators interested in assembling tools derived from different sources to create alternative approaches to actor training. While the process outlined in the book evolves in a classroom setting, the components of the pedagogy can also be practiced by individuals who are interested in finding new ways to explore text and character and bring them into their own personal practice.

Re-Purposing Suzuki

Re-Purposing Suzuki PDF Author: Maria Porter
Publisher: Routledge
ISBN: 1000475840
Category : Performing Arts
Languages : en
Pages : 159

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Book Description
Re-Purposing Suzuki: A Hybrid Approach to Actor Training introduces a system of text analysis that synthesizes physical, psychological, and vocal components in order to truthfully embody heightened texts and contexts. By understanding how the author has re-purposed Suzuki and other physical training methods, as well as Stanislavski, readers will gain an awareness of how to analyze a particular training method by extrapolating its key components and integrating it into a holistic, embodied approach to text analysis. The book explores a method of physical scoring via Rules of the Body and Rules of Composition, as well as a method of approaching heightened texts from Greek drama to post-modern playwrights that draws on the individual actor’s imagination and experience and integrates voice, mind, and body. Readers will be able to either replicate this approach, or apply the logic of its building blocks to assemble their own personal creative process applicable to a variety of performance genres. This is a source book for actors, theatre students, practitioners, and educators interested in assembling tools derived from different sources to create alternative approaches to actor training. While the process outlined in the book evolves in a classroom setting, the components of the pedagogy can also be practiced by individuals who are interested in finding new ways to explore text and character and bring them into their own personal practice.

Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders

Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders PDF Author: Anna R. Carta
Publisher: Frontiers Media SA
ISBN: 2889741680
Category : Science
Languages : en
Pages : 337

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Book Description


Drug Repurposing

Drug Repurposing PDF Author: Farid A. Badria
Publisher: BoD – Books on Demand
ISBN: 1839685204
Category : Medical
Languages : en
Pages : 236

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Book Description
Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

Drug Repurposing for Emerging Infectious Diseases and Cancer

Drug Repurposing for Emerging Infectious Diseases and Cancer PDF Author: Ranbir Chander Sobti
Publisher: Springer Nature
ISBN: 9811953996
Category : Medical
Languages : en
Pages : 664

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Book Description
​This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.

Drug Repurposing

Drug Repurposing PDF Author: David Cavalla
Publisher: Royal Society of Chemistry
ISBN: 1788019032
Category : Business & Economics
Languages : en
Pages : 351

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Book Description
Drug repurposing, or repositioning, is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. This book provides an ideal introduction to the field of drug repurposing with contributions from world-renowned experts culminating in an excellent resource for any drug discovery or medicinal chemist.

Drug Repurposing

Drug Repurposing PDF Author: Ramarao Poduri
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110791528
Category : Science
Languages : en
Pages : 352

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Book Description
Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.

Drug Repurposing

Drug Repurposing PDF Author: Shailendra K. Saxena
Publisher: BoD – Books on Demand
ISBN: 1839699574
Category : Medical
Languages : en
Pages : 385

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Book Description
This book focuses on various aspects and applications of drug repurposing, the understanding of which is important for treating diseases. Due to the high costs and time associated with the new drug discovery process, the inclination toward drug repurposing is increasing for common as well as rare diseases. A major focus of this book is understanding the role of drug repurposing to develop drugs for infectious diseases, including antivirals, antibacterial and anticancer drugs, as well as immunotherapeutics.

Building Embodiment

Building Embodiment PDF Author: Baron Kelly
Publisher: Taylor & Francis
ISBN: 100089603X
Category : Performing Arts
Languages : en
Pages : 182

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Book Description
Building Embodiment: Integrating Acting, Voice, and Movement to Illuminate Poetic Text offers a collection of strategic and practical approaches to understanding, analyzing, and embodying a range of heightened text styles, including Greek tragedy, Shakespeare, and Restoration/comedy of manners. These essays offer insights from celebrated teachers across the disciplines of acting, voice, and movement and are designed to help actors and instructors find deeper vocal and physical connections to poetic text. Although each dramatic genre offers a unique set of challenges, Building Embodiment highlights instances where techniques can be integrated, revealing how the synthesis of body, brain, and word results in a fuller sense of character experiencing for both the actor and the audience. This book bridges the gap between academic and professional application and invites the student and professional actor into a richer experience of character and story.

The Routledge Companion to Theatre and Performance

The Routledge Companion to Theatre and Performance PDF Author: Paul Allain
Publisher: Taylor & Francis
ISBN: 1040127797
Category : Performing Arts
Languages : en
Pages : 389

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Book Description
What is theatre? What is performance? What connects them and how are they different? How have they been shaped by events, people, companies, practices and ideas in the twentieth and twenty-first centuries? And where are they heading next? The Routledge Companion to Theatre and Performance offers some answers to these big questions. This third edition has been updated to now include over 160 entries, with all entries brought up to date and new topics added, including Caryl Churchill, Black Lives Matter and Hamilton, among others. This book provides an accessible, informative and engaging introduction to important people and companies, events, concepts and practices that have defined the complementary fields of theatre and performance studies. Three easy-to-use alphabetized sections include entries on topics and people ranging from performance artists Marina Abramović and Pope.L to directors Vsevolod Meyerhold and Robert Wilson, the haka, Taking the Knee and disability, theatre and performance. Each entry includes important historical and contextual information, extensive cross-referencing, detailed analysis and an annotated bibliography. The Routledge Companion to Theatre and Performance is a perfect reference guide for the keen student and the passionate theatre-goer alike.

Drug Repurposing and Repositioning

Drug Repurposing and Repositioning PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309302072
Category : Medical
Languages : en
Pages : 95

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Book Description
Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs - a process referred to as drug repurposing or repositioning. Historically, drug repurposing has been largely an unintentional, serendipitous process that took place when a drug was found to have an offtarget effect or a previously unrecognized on-target effect that could be used for identifying a new indication. Perhaps the most recognizable example of such a successful repositioning effort is sildenafil. Originally developed as an anti-hypertensive, sildenafil, marketed as Viagra and under other trade names, has been repurposed for the treatment of erectile dysfunction and pulmonary arterial hypertension. Viagra generated more than $2 billion worldwide in 2012 and has recently been studied for the treatment of heart failure. Given the widespread interest in drug repurposing, the Roundtable on Translating Genomic-Based Research for Health of the Institute of Medicine hosted a workshop on June 24, 2013, in Washington, DC, to assess the current landscape of drug repurposing activities in industry, academia, and government. Stakeholders, including government officials, pharmaceutical company representatives, academic researchers, regulators, funders, and patients, were invited to present their perspectives and to participate in workshop discussions. Drug Repurposing and Repositioning is the summary of that workshop. This report examines enabling tools and technology for drug repurposing; evaluates the business models and economic incentives for pursuing a repurposing approach; and discusses how genomic and genetic research could be positioned to better enable a drug repurposing paradigm.