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Author: Jo-Anne Bright
Publisher: CRC Press
ISBN: 0429671423
Category : Law
Languages : en
Pages : 192
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Book Description
DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.
Author: Jo-Anne Bright
Publisher: CRC Press
ISBN: 0429671423
Category : Law
Languages : en
Pages : 192
Get Book Here
Book Description
DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.
Author: Lila Monroe
Publisher: Lila Monroe Books
ISBN:
Category : Fiction
Languages : en
Pages : 245
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Book Description
Author:
Publisher: John Wiley & Sons
ISBN: 0470018267
Category : Medical
Languages : en
Pages : 405
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Book Description
The Encyclopedia of Forensic Sciences provides a comprehensive, definitive, and up to date reference of the main areas of specialist and expert knowledge and skills used by those involved in all aspects of the forensic process, including, but not limited to forensic scientists, doctors, practicing and academic lawyers, para-legals, police, crime scene investigators, analytical chemists, toxicologists, etc. The Encyclopedia of Forensic Sciences covers all areas of specialist and expert knowledge and skill which, either as part of an established forensic discipline or as a potentially useful emerging discipline, are of interest to those involved in the forensic process. This includes both the scientific methodology and the admissibility of evidence. The encyclopedia also includes case studies of landmark cases in the definition and practice of forensic science. The Encyclopedia of Forensic Sciences presents all material on a level and in a style that makes it accessible to a wide range of readers. Lawyers will be able to understand the science behind scientific evidence, scientists will understand the legal aspects, physical scientists will have access to biological and social sciences aspects and vice versa.
Author: John Haigh
Publisher: Winning with Probability
ISBN: 0198526636
Category : Mathematics
Languages : en
Pages : 388
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Book Description
"What are the odds against winning the Lotto, The Weakest Link, or Who Wants to be a Millionaire? The answer lies in the science of probability, yet many of us are unaware of how this science works. Every day, people make judgements on a wide variety of situations where chance plays a role, including buying insurance, betting on horse-racing, following medical advice - even carrying an umbrella. In Taking Chances, John Haigh guides the reader round common pitfalls, demonstrates how to make better-informed decisions, and shows where the odds can be unexpectedly in your favour. This new edition has been fully updated, and includes information on top television shows, plus a new chapter on Probability for Lawyers."--BOOK JACKET.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 78
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Book Description
LIFE Magazine is the treasured photographic magazine that chronicled the 20th Century. It now lives on at LIFE.com, the largest, most amazing collection of professional photography on the internet. Users can browse, search and view photos of today’s people and events. They have free access to share, print and post images for personal use.
Author: Santiago Barreda
Publisher: Taylor & Francis
ISBN: 1000869784
Category : Psychology
Languages : en
Pages : 485
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Book Description
This comprehensive book is an introduction to multilevel Bayesian models in R using brms and the Stan programming language. Featuring a series of fully worked analyses of repeated measures data, the focus is placed on active learning through the analyses of the progressively more complicated models presented throughout the book. In this book, the authors offer an introduction to statistics entirely focused on repeated measures data beginning with very simple two-group comparisons and ending with multinomial regression models with many ‘random effects’. Across 13 well-structured chapters, readers are provided with all the code necessary to run all the analyses and make all the plots in the book, as well as useful examples of how to interpret and write up their own analyses. This book provides an accessible introduction for readers in any field, with any level of statistical background. Senior undergraduate students, graduate students, and experienced researchers looking to ‘translate’ their skills with more traditional models to a Bayesian framework will benefit greatly from the lessons in this text.
Author: Michael J. Marsh
Publisher: Lulu.com
ISBN: 1257971123
Category :
Languages : en
Pages : 104
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Book Description
Author: Verlyn Klinkenborg
Publisher: Vintage
ISBN: 0307958493
Category : Language Arts & Disciplines
Languages : en
Pages : 225
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Book Description
Most of what you think you know about writing is useless. It’s the harmful debris of your education—a mixture of half-truths, myths, and false assumptions that prevents you from writing well. Drawing on years of experience as a writer and teacher of writing, Verlyn Klinkenborg offers an approach to writing that will change the way you work and think. There is no gospel, no orthodoxy, no dogma in this book. What you’ll find here isn’t the way to write. Instead, you’ll find a way to clear your mind of illusions about writing and discover how you write. Several Short Sentences About Writing is a book of first steps and experiments. They will revolutionize the way you think and perceive, and they will change forever the sense of your own authority as a writer. This is a book full of learning, but it’s also a book full of unlearning—a way to recover the vivid, rhythmic, poetic sense of language you once possessed. An indispensable and unique book that will give you a clear understanding of how to think about what you do when you write and how to improve the quality of your writing.
Author: André Leroi-Gourhan
Publisher: MIT Press
ISBN: 9780262121736
Category : Art
Languages : en
Pages : 496
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Book Description
Combines in one volume "Technics and Language", in which anthropologist Leroi-Gourhan looks at prehistoric technology in relation to the development of cognitive and liguistic faculties, and "Memory and Rhythms", which addresses instinct and intelligence from a sociological viewpoint.
Author: W. Mark Dale
Publisher: CRC Press
ISBN: 1040083676
Category : Business & Economics
Languages : en
Pages : 263
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Book Description
New technologies, including DNA and digital databases that can compare known and questioned exemplars, have transformed forensic science and greatly impacted the investigative process. They have also made the work more complicated. Obtaining proper resources to provide quality and timely forensic services is frequently a challenge for forensic managers, who are often promoted from casework duties and must now learn a whole new set of leadership skills. The interdisciplinary and scientific nature of laboratories requires strong leadership ability to manage complex issues, often in adversarial settings. Forensic Laboratory Management: Applying Business Principles provides laboratory managers with business tools that apply the best science to the best evidence in a manner that increases the efficiency and effectiveness of their management decision making. The authors present a performance model with seven recommendations to implement, illustrating how forensic managers can serve as leaders and strategically improve the operation and management in scientific laboratories. Topics include: Key business metrics and cost–benefit analyses Ethical lapses: why they occur, possible motives, and how problems can be prevented Forensic training, education, and institutes ISO/IEC 17025 accreditation implementation The book includes case studies simulating a working laboratory in which readers can apply business tools with actual data reinforcing discussion concepts. Each chapter also includes a brief review of current literature of the best management theories and practice. The downloadable resources supply two mock trial transcripts and associated case files along with PowerPoint® slides from Dr. George Carmody’s workshop on Forensic DNA Statistics and Dr. Doug Lucas’s presentation on ethics.
