Quantitative Methods in Neuroscience PDF Download
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Author: Stephen M. Evans
Publisher: Oxford University Press, USA
ISBN: 0198505280
Category : Medical
Languages : en
Pages : 349
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Book Description
Stereology is a valuable tool for scientists, allowing them to make 3-D reconstructions of the brain from 2-D data. This is a 'cookbook' of stereological methods written especially for neuroscientists, with clear advice about when and when not to use stereology
Author: Stephen M. Evans
Publisher: Oxford University Press, USA
ISBN: 0198505280
Category : Medical
Languages : en
Pages : 349
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Book Description
Stereology is a valuable tool for scientists, allowing them to make 3-D reconstructions of the brain from 2-D data. This is a 'cookbook' of stereological methods written especially for neuroscientists, with clear advice about when and when not to use stereology
Author: Stephen M Evans
Publisher: Oxford University Press
ISBN: 0191500097
Category : Medical
Languages : en
Pages :
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Book Description
Stereology is a valuable tool for neuroscientists, allowing them to obtain 3-Dimensional information from 2-Dimensional measurements made on appropriately sampled sections (usually obtained from histological sections or MRI/CT/PET scans). This 3-D information is invaluable in correlating structural/functional relationships in the pursuit of far greater understanding of the function of the central nervous system. However, in carrying out such measurements, often based on limited data sets, there is a risk of experimenter bias. An important feature of modern design based stereology is to be aware of potential sources of bias and eliminate them during the data collection. With many of the major neuroscience journals now insisting that quantitative data be presented, there is a greater need than ever for neuroscientists to understand the theory and practice behind quantitative methods, such as those offered by stereology. Quantitative Methods in Neuroscience is a cookbook of stereological methods written especially for neuroscientists. It provides clear and accessible advice about when and when not to use stereology. Throughout the book, the emphasis is on practical guidance, rather than discussions and formulae. Written by leading scientists in the field of stereology, with a Foreword by D.C. Sterio, the book will be a valuable introduction to these methods for neuroscientists, and all those involved in development of new drug programmes.
Author: Aaron Newman
Publisher: SAGE
ISBN: 1473952980
Category : Psychology
Languages : en
Pages : 1006
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Book Description
This fresh, new textbook provides a thorough and student-friendly guide to the different techniques used in cognitive neuroscience. Given the breadth of neuroimaging techniques available today, this text is invaluable, serving as an approachable text for students, researchers, and writers. This text provides the right level of detail for those who wish to understand the basics of neuroimaging and also provides more advanced material in order to learn further about particular techniques. With a conversational, student-friendly writing style, Aaron Newman introduces the key principles of neuroimaging techniques, the relevant theory and the recent changes in the field.
Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416
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Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step
Author: Zhe Chen
Publisher: Springer
ISBN: 3319719769
Category : Technology & Engineering
Languages : en
Pages : 337
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Book Description
This book shows how to develop efficient quantitative methods to characterize neural data and extra information that reveals underlying dynamics and neurophysiological mechanisms. Written by active experts in the field, it contains an exchange of innovative ideas among researchers at both computational and experimental ends, as well as those at the interface. Authors discuss research challenges and new directions in emerging areas with two goals in mind: to collect recent advances in statistics, signal processing, modeling, and control methods in neuroscience; and to welcome and foster innovative or cross-disciplinary ideas along this line of research and discuss important research issues in neural data analysis. Making use of both tutorial and review materials, this book is written for neural, electrical, and biomedical engineers; computational neuroscientists; statisticians; computer scientists; and clinical engineers.
Author: Uwe Windhorst
Publisher: Springer Science & Business Media
ISBN: 3642585523
Category : Medical
Languages : en
Pages : 1336
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Book Description
An overview of the techniques used in modern neuroscience research with the emphasis on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. This is essentially a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters and protocols are organized such that they can be used independently, while cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.
Author: Adalberto Merighi
Publisher: Springer Science & Business Media
ISBN: 0387224602
Category : Medical
Languages : en
Pages : 307
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Book Description
There are numerous books on cellular and molecular protocols for general use in cell biology but very few are exclusively devoted to neurobiology. This book fills this gap and explains in a clear and consistent manner, some of the more commonly used protocols in neuroscience research. Each chapter is written by either the person who invented the procedure or an expert in the field. The format is uniform: "Overview," "Background," "Protocols," and "results and discussion." Each protocol begins with the principle of the technique, studies in cell culture, materials and reagents, and, lastly, step-by-step outline of the procedure itself. This highly practical book is also well illustrated (with 17 four color plates) to make the concepts and procedures easy to understand and perform.
Author: Panos M. Pardalos
Publisher: Springer Science & Business Media
ISBN: 1461302250
Category : Technology & Engineering
Languages : en
Pages : 263
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Book Description
Advances in the field of signal processing, nonlinear dynamics, statistics, and optimization theory, combined with marked improvement in instrumenta tion and development of computers systems, have made it possible to apply the power of mathematics to the task of understanding the human brain. This verita ble revolution already has resulted in widespread availability of high resolution neuroimaging devices in clinical as well as research settings. Breakthroughs in functional imaging are not far behind. Mathematical tech niques developed for the study of complex nonlinear systems and chaos already are being used to explore the complex nonlinear dynamics of human brain phys iology. Global optimization is being applied to data mining expeditions in an effort to find knowledge in the vast amount of information being generated by neuroimaging and neurophysiological investigations. These breakthroughs in the ability to obtain, store and analyze large datasets offer, for the first time, exciting opportunities to explore the mechanisms underlying normal brain func tion as well as the affects of diseases such as epilepsy, sleep disorders, movement disorders, and cognitive disorders that affect millions of people every year. Ap plication of these powerful tools to the study of the human brain requires, by necessity, collaboration among scientists, engineers, neurobiologists and clini cians. Each discipline brings to the table unique knowledge, unique approaches to problem solving, and a unique language.
Author: Michael G. Stewart
Publisher: Open University Press
ISBN: 9780335093243
Category : Autoradiography
Languages : en
Pages : 272
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Book Description
Author: Rosemary Martin
Publisher: CRC Press
ISBN: 1000725359
Category : Science
Languages : en
Pages : 280
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Book Description
Unique in its coverage of such an extensive range of methods, Neuroscience Methods: A Guide for Advanced Students provides easy-to-understand descriptions of the many different techniques that are currently being used to study the brain at the molecular and cellular levels. This valuable reference text will help rescue undergraduate and postgraduate students from continuing bewilderment at the methods sections of current neuroscience publications. Topics covered include in vivo and in vitro preparations, electrophysiological, histochemical, hybridization and genetic techniques, measurement of cellular ion concentrations, methods of drug application, production of antibodies, expression systems, and neural grafting.
