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Author: T.W. Stone
Publisher: Springer Science & Business Media
ISBN: 9401139113
Category : Medical
Languages : en
Pages : 265
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Book Description
Many groups of biologically important compounds experience cycles of furious research activity and near oblivion. The purines however seem not to be falling into such a pattern. Interest seems to be continuing almost exponentially with no sign of diminution. The result is a frighteningly extensive literature and an increas ing demand for international conferences and symposia. Unfortunately meetings such as these also spawn increasingly voluminous proceedings and it becomes more and more difficult for a newcomer to the area, or a non specialist, to obtain the general introductory survey he needs. This volume therefore is not intended to be comprehensive - far from it. We have tried to be selective in the material presented and the references quoted. They should provide a quick guide and access to key works in the literature which can be expanded by library or computerised searching. We hope that our efforts will widen the appreciation of purines as biologically important substances and will herald the day when more purine related drugs than the handful currently available are used for the selective treatment of disease. We are grateful to the many authors and publishers who have given permission to reproduce figures or quote unpublished results, and to Anne Stone for her patient typing of the manuscript.
Author: T.W. Stone
Publisher: Springer Science & Business Media
ISBN: 9401139113
Category : Medical
Languages : en
Pages : 265
Get Book Here
Book Description
Many groups of biologically important compounds experience cycles of furious research activity and near oblivion. The purines however seem not to be falling into such a pattern. Interest seems to be continuing almost exponentially with no sign of diminution. The result is a frighteningly extensive literature and an increas ing demand for international conferences and symposia. Unfortunately meetings such as these also spawn increasingly voluminous proceedings and it becomes more and more difficult for a newcomer to the area, or a non specialist, to obtain the general introductory survey he needs. This volume therefore is not intended to be comprehensive - far from it. We have tried to be selective in the material presented and the references quoted. They should provide a quick guide and access to key works in the literature which can be expanded by library or computerised searching. We hope that our efforts will widen the appreciation of purines as biologically important substances and will herald the day when more purine related drugs than the handful currently available are used for the selective treatment of disease. We are grateful to the many authors and publishers who have given permission to reproduce figures or quote unpublished results, and to Anne Stone for her patient typing of the manuscript.
Author: T.W. Stone
Publisher: Springer
ISBN: 9789401057417
Category : Medical
Languages : en
Pages : 0
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Book Description
Many groups of biologically important compounds experience cycles of furious research activity and near oblivion. The purines however seem not to be falling into such a pattern. Interest seems to be continuing almost exponentially with no sign of diminution. The result is a frighteningly extensive literature and an increas ing demand for international conferences and symposia. Unfortunately meetings such as these also spawn increasingly voluminous proceedings and it becomes more and more difficult for a newcomer to the area, or a non specialist, to obtain the general introductory survey he needs. This volume therefore is not intended to be comprehensive - far from it. We have tried to be selective in the material presented and the references quoted. They should provide a quick guide and access to key works in the literature which can be expanded by library or computerised searching. We hope that our efforts will widen the appreciation of purines as biologically important substances and will herald the day when more purine related drugs than the handful currently available are used for the selective treatment of disease. We are grateful to the many authors and publishers who have given permission to reproduce figures or quote unpublished results, and to Anne Stone for her patient typing of the manuscript.
Author: David S. Newcombe
Publisher: Springer Science & Business Media
ISBN: 1447142640
Category : Medical
Languages : en
Pages : 410
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Book Description
Gout: Basic Science and Clinical Practice is a thoroughly researched comprehensive text which covers all important aspects of gout, including its genetics, pathophysiology, diagnosis, and management. Gout is probably the most common rheumatic disease after osteoarthritis and is becoming more common with the prevalence of the metabolic syndrome in the US, and in many other countries. Only about 10% of patients with gout are treated by rheumatologists and this often leads to inadequate diagnosis and treatment in general medical practice. Written by an expert in the field this book is valuable reference for rheumatologists and others in the medical profession who are interested in understanding and managing this important disease.
Author: Ursula Gresser
Publisher: Springer Science & Business Media
ISBN: 3642849628
Category : Science
Languages : en
Pages : 188
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Book Description
Inherited disorders of purine and pyrimidine metabolism in man lead to severe diseases. At the 2nd M}nchner Adventssymposium the state of the art as to the genetic basis, clinical aspects, and the biochemical basis has been given by leading experts in the fields concerning the following diseases: Hypoxanthine phosphoribosyltransferase deficiency (HGPRT-deficieny), adenine phosphoribosyltransferase deficiency (APRT-deficiency), hyperuricemia and gout, adenosine deaminase deficiency (ADA-deficiency, purine nucleoside phosphorylase deficiency (PNP-deficiency). All contributions of the symposium are published within this volume thus giving and overview of this most interesting field.
Author: Andrea Griesmacher
Publisher: Springer Science & Business Media
ISBN: 1461553814
Category : Science
Languages : en
Pages : 816
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Book Description
th th This volume comprizes articles presented at the joint IX International and 6 Euro pean Symposium on Purine and Pyrimidine Metabolism in Man held in Gmunden, Austria, June 1 through 7, 1997. Since the first of this series of meetings was held in Israel in 1973, conventions were organized every three years in different parts of the world including the USA, Japan, and Europe. The different aspects of purine and pyrimidine metabolism bring together re searchers working in molecular genetics, biochemical pharmacology, biochemistry, devel opmental biology, immunology, epidemiology and the clinics. Oriented research in the field has been seminal for the development of potent anticancer and antiviral drugs. As the number of genes which are cloned, grows, the understanding of metabolism is increas ingly enlarged and might provide leads to further improve therapeutic concepts and to bet ter understand mechanisms responsible for the development of resistance against these drugs. In certain diseases purine and pyrimidine analogs represent not only the drugs of choice but in fact are the sole therapeutic alternative at present. The field has also taken an early lead in attempting to correct inborn errors of purine and pyrimidine metabolism by gene therapy. The organization of this meeting involved a large number of people who dedicated their time in an effort to make this symposium a success. We thank the Abstract Review Committee, the International Advisory Board and in particular the Symposium Secretariat for doing a wonderful job.
Author: David A. Warrell
Publisher:
ISBN: 0192629220
Category : Medical
Languages : en
Pages : 4436
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Book Description
The Oxford Textbook of Medicine provides all that any doctor needs to know to practice top-level internal medicine. It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders. There are major introductory sections on the scientific basis of disease; and in the system-based clinical sections genetic predisposition, pathophysiology, pathogenesis, molecular mechanisms, and cell biology are covered in depth for all significant medical syndromes. Clinical descriptions of diseases are clearly and memorably written, based on the experience and insight of the authors--many of whom are among the world's most distinguished medical scientists. Chapters are not only "evidence based" but also on clinical experience and a thorough survey of all the relevant literature. Throughout, the approach of OTM is humane and ethical and, at the same time, factual, reliable, honest(especially where knowledge is limited) and rigorously scientific. This is not just a textbook of "First World" medicine. It provides practical guidance for doctors working in a variety of medical setting the value of a logical clinical approach rather than immediate resort to expensive imaging and laboratory tests. Moore of the contributing authors than ever before are from outside Europe, including strong representation of North American medicine. The new editorial team has ensured that the OTM continues to reflect rapid changes in medical practice: there are new sections on intensive care, alcohol and drug abuse, clinical pharmacology and therapeutics, world health, clinical trials and evidence-based medicine, adolescent medicine, sports medicine, and emergency medicine; more than half the contributors are new for this edition; and most of the text has been heavily revised. The striking new page and cover design reflect the significant changes made in this new edition. The Textbook is illustrated by over 2000 two-color diagrams and many color Plates. The index is the most detailed and user-friendly of any major medical textbook: in an emergency, the reader can access information quickly- whether on the ward, in office or at home. Like its predecessors, OTM4 will be the trusted and ultimate reference in libraries, hospitals, doctors' consulting rooms, solicitors' offices, press offices, and primary care practices worldwide.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 690
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Michelle Kenyon
Publisher: Springer
ISBN: 3319500260
Category : Medical
Languages : en
Pages : 318
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Book Description
This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.
Author: Lee W. Janson
Publisher: McGraw Hill Professional
ISBN: 0071637923
Category : Medical
Languages : en
Pages : 431
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Book Description
Get the BIG PICTURE of Medical Biochemistry – and target what you really need to know to ace the course exams and the USMLE Step 1 300 FULL-COLOR ILLUSTRATIONS Medical Biochemistry: The Big Picture is a unique biochemistry review that focuses on the medically applicable concepts and techniques that form the underpinnings of the diagnosis, prognosis, and treatment of medical conditions. Those preparing for the USMLE, residents, as well as clinicians who desire a better understanding of the biochemistry behind a particular pathology will find this book to be an essential reference. Featuring succinct, to-the-point text, more than 300 full-color illustrations, and a variety of learning aids, Medical Biochemistry: The Big Picture is designed to make complex concepts understandable in the shortest amount of time possible. This full-color combination text and atlas features: Progressive chapters that allow you to build upon what you’ve learned in a logical, effective manner Chapter Overviews that orient you to the important concepts covered in that chapter Numerous tables and illustrations that clarify and encapsulate the text Sidebars covering a particular disease or treatment add clinical relevance to topic discussed Essay-type review questions at the end of each chapter allow you to assess your comprehension of the major topics USMLE-style review questions at the end of each section Three appendices, including examples of biochemically based diseases, a review of basic biochemical techniques, and a review of organic chemistry/biochemistry
Author: Gernot Riedel
Publisher: Springer Science & Business Media
ISBN: 9780306478628
Category : Medical
Languages : en
Pages : 646
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Book Description
The decade of the brain has brought us a few steps closer to some of the key questions in neuroscience. The complexity of memory is seen on the systems and cellular level, and different types of memory are implemented in several cellular changes that can interact, or work independently. From Messengers to Molecules: Memories are Made of These, follows the arguments from different research teams for their particular area of expertise. All chapters are written to stand-alone and provide an up-to-date introduction to the topic for both specialists and novices alike. As a result, a comprehensive compendium covering cellular mechanisms contributing to memory formation in an unusual breadth has emerged. This books will be of interest to researchers working on the pharmacology, physiology and genetics of memory formation, clinicians memory disorders, industry and students in advanced courses in Neuroscience or Pharmacology.
