Newton's Principia revisited

Newton's Principia revisited PDF Author: Michael Schmiechen
Publisher: BoD – Books on Demand
ISBN: 3837053083
Category :
Languages : en
Pages : 610

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Book Description
PROBLEM. The treatise is devoted to the reconstruction of our 'instinctive beliefs' in classical mechanics and to present them 'as much isolated and as free from irrelevant additions as possible'. The same motivation has driven many authors since the publication of Newton's Principia. IMPORTANCE. Classical mechanics will remain the basic reference and tool for mechanics on terrestrial and planetary scale as well as the proto-theory of relativistic and quantum mechanics. But it can only serve its purpose if it is not considered as obsolete, but if its foundations and implications are understood and made 'absolutely' clear. METHOD. Based on the 'instinctive belief' that the foundations of classical mechanics cannot be found and reconstructed within mechanics itself but only 'outside', classical mechanics is 'understood' by embedding it into an adequate theory of knowledge and adequate proto- and meta-theories in terms of the 'language of dynamics'. Evidence is produced that available philosophical expositions are not adequate for the purpose at hand. Mechanics is treated as part of physics, not of mathematics. Not sophisticated mathematical artifacts, necessary for solving specific problems, but the intellectually satisfactory foundation of mechanics in general is subject and purpose of the exercise. The goal is reached using axiomatic systems as models. SCOPE. Following an account of the unsatisfactory state of affairs the treatise covers the epistemological foundations, abstract proto-mechanics, i. e. the theories of time and space, meta-mechanics, i. e. the theories of state space models and of quantities proper, and, as an instance of the latter, abstract elementary mechanics, the theory of translational motions of 'small' solid bodies in three-dimensional Euclidean space, including classical general relativity. Subsequently the theory of classical kinematics is developed as basis for interpreted proto-mechanics and interpreted elementary mechanics. As an amus

Newton's Principia revisited

Newton's Principia revisited PDF Author: Michael Schmiechen
Publisher: BoD – Books on Demand
ISBN: 3837053083
Category :
Languages : en
Pages : 610

Get Book Here

Book Description
PROBLEM. The treatise is devoted to the reconstruction of our 'instinctive beliefs' in classical mechanics and to present them 'as much isolated and as free from irrelevant additions as possible'. The same motivation has driven many authors since the publication of Newton's Principia. IMPORTANCE. Classical mechanics will remain the basic reference and tool for mechanics on terrestrial and planetary scale as well as the proto-theory of relativistic and quantum mechanics. But it can only serve its purpose if it is not considered as obsolete, but if its foundations and implications are understood and made 'absolutely' clear. METHOD. Based on the 'instinctive belief' that the foundations of classical mechanics cannot be found and reconstructed within mechanics itself but only 'outside', classical mechanics is 'understood' by embedding it into an adequate theory of knowledge and adequate proto- and meta-theories in terms of the 'language of dynamics'. Evidence is produced that available philosophical expositions are not adequate for the purpose at hand. Mechanics is treated as part of physics, not of mathematics. Not sophisticated mathematical artifacts, necessary for solving specific problems, but the intellectually satisfactory foundation of mechanics in general is subject and purpose of the exercise. The goal is reached using axiomatic systems as models. SCOPE. Following an account of the unsatisfactory state of affairs the treatise covers the epistemological foundations, abstract proto-mechanics, i. e. the theories of time and space, meta-mechanics, i. e. the theories of state space models and of quantities proper, and, as an instance of the latter, abstract elementary mechanics, the theory of translational motions of 'small' solid bodies in three-dimensional Euclidean space, including classical general relativity. Subsequently the theory of classical kinematics is developed as basis for interpreted proto-mechanics and interpreted elementary mechanics. As an amus

Responsible Research

Responsible Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309084881
Category : Medical
Languages : en
Pages : 313

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Book Description
When 18-year-old Jesse Gelsinger died in a gene transfer study at the University of Pennsylvania, the national spotlight focused on the procedures used to ensure research participants' safety and their capacity to safeguard the well-being of those who volunteer for research studies. Responsible Research outlines a three-pronged approach to ensure the protection of every participant through the establishment of effective Human Research Participant Protection Programs (HRPPPs). The approach includes: Improved research review processes, Recognition and integration of research participants' contributions to the system, and Vigilant maintenance of HRPPP performance. Issues addressed in the book include the need for in-depth, complimentary reviews of science, ethics, and conflict of interest reviews; desired qualifications for investigators and reviewers; the process of informed consent; federal and institutional oversight; and the role of accreditation. Recommendations for areas of key interest include suggestions for legislative approaches, compensation for research-related injury, and the refocusing of the mission of institutional review boards. Responsible Research will be important to anyone interested in the issues that are relevant to the practice of using human subjects as research participants, but especially so to policy makers, research administrators, investigators, and research sponsorsâ€"but also including volunteers who may agree to serve as research participants.

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research PDF Author: John I. Gallin
Publisher: Academic Press
ISBN: 0123821681
Category : Science
Languages : en
Pages : 797

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Book Description
The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. - Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research - Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research - Delves into data management and addresses how to collect data and use it for discovery - Contains valuable, up-to-date information on how to obtain funding from the federal government

Adolescent Medicine

Adolescent Medicine PDF Author: Gail B. Slap
Publisher: Elsevier Health Sciences
ISBN: 032304073X
Category : Medical
Languages : en
Pages : 350

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Book Description
This concise, evidence-based resource covers all of today's need-to-know information to quickly and effectively diagnose and manage common adolescent conditions...in an exceptionally user-friendly format. Because it's so compact, clinically oriented, and easy to read, Adolescent Medicine: The Requisites in Pediatrics is an ideal study tool as well as a convenient reference for practice. Includes detailed discussions on special health issues, common medical problems, sexual and reproductive health, behavioral problems, and the transition to adult health care to help you gain a better understanding of the unique needs of the adolescent patient. Features a logical, consistent chapter format that helps you find the guidance you need quickly. Presents abundant tables, differential diagnoses, lab values/radiologic studies, treatment/therapy recommendations, and guidance on when to refer to a specialist equipping you for every clinical challenge. Discusses controversies concerning the standard of care with the aid of thought-provoking clinical scenarios to help you to determine the best course of action in difficult situations. Provides highlighted boxes that emphasize relevant case studies, key points of each section, and other important information making you aware of considerations that impact today's practice. Uses a wealth of illustrations so you can see details more clearly.

Ethical Conduct of Clinical Research Involving Children

Ethical Conduct of Clinical Research Involving Children PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309091810
Category : Medical
Languages : en
Pages : 446

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Book Description
In recent decades, advances in biomedical research have helped save or lengthen the lives of children around the world. With improved therapies, child and adolescent mortality rates have decreased significantly in the last half century. Despite these advances, pediatricians and others argue that children have not shared equally with adults in biomedical advances. Even though we want children to benefit from the dramatic and accelerating rate of progress in medical care that has been fueled by scientific research, we do not want to place children at risk of being harmed by participating in clinical studies. Ethical Conduct of Clinical Research Involving Children considers the necessities and challenges of this type of research and reviews the ethical and legal standards for conducting it. It also considers problems with the interpretation and application of these standards and conduct, concluding that while children should not be excluded from potentially beneficial clinical studies, some research that is ethically permissible for adults is not acceptable for children, who usually do not have the legal capacity or maturity to make informed decisions about research participation. The book looks at the need for appropriate pediatric expertise at all stages of the design, review, and conduct of a research project to effectively implement policies to protect children. It argues persuasively that a robust system for protecting human research participants in general is a necessary foundation for protecting child research participants in particular.

The NIH Catalyst

The NIH Catalyst PDF Author:
Publisher:
ISBN:
Category : Electronic government information
Languages : en
Pages : 16

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Book Description


Magical Epistemologies

Magical Epistemologies PDF Author: Anannya Dasgupta
Publisher: Routledge
ISBN: 1000417530
Category : Literary Criticism
Languages : en
Pages : 152

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Book Description
This book began with a simple question: when readers such as us encounter the term magic or figures of magicians in early modern texts, dramatic or otherwise, how do we read them? In the twenty-first century we have recourse to an array of genres and vocabulary from magical realism to fantasy fiction that does not, however, work to read a historical figure like John Dee or a fictional one he inspired in Shakespeare's Prospero. Between longings to transcend human limitation and the actual work of producing, translating, and organizing knowledge, figures such as Dee invite us to re-examine our ways of reading magic only as metaphor. If not metaphor then what else? As we parse the term magic, it reveals a rich context of use that connects various aspects of social, cultural, religious, economic, legal and medical lives of the early moderns. Magic makes its presence felt not only as a forms of knowledge but in methods of knowing in the Renaissance. The arc of dramatists and texts that this book draws between Doctor Faustus, The Tempest, The Alchemist and Comus: A Masque at Ludlow Castle offers a sustained examination of the epistemologies of magic in the context of early modern knowledge formation. Please note: Taylor & Francis does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

Forever Peace

Forever Peace PDF Author: Joe Haldeman
Publisher: Penguin
ISBN: 1101666196
Category : Fiction
Languages : en
Pages : 367

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Book Description
2043 A.D.: The Ngumi War rages. A burned-out soldier and his scientist lover discover a secret that could put the universe back to square one. And it is not terrifying. It is tempting...

Guidelines for the Conduct of Research Involving Human Subjects at the National Institutes of Health

Guidelines for the Conduct of Research Involving Human Subjects at the National Institutes of Health PDF Author: National Institutes of Health (U.S.)
Publisher:
ISBN:
Category : Human experimentation in medicine
Languages : en
Pages : 32

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Book Description


Europe, America, and Technology: Philosophical Perspectives

Europe, America, and Technology: Philosophical Perspectives PDF Author: P.T. Durbin
Publisher: Springer Science & Business Media
ISBN: 9401132429
Category : Philosophy
Languages : en
Pages : 262

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Book Description
As Europe moves toward 1992 and full economic unity, and as Eastern Europe tries to find its way in the new economic order, the United States hesitates. Will the new European economic order be good for the U.S. or not? Such a question is exacerbated by world-wide changes in the technological order, most evident in Japan's new techno-economic power. As might be expected, philosophers have been slow to come to grips with such issues, and lack of interest is compounded by different philosophical styles in different parts of the world. What this volume addresses is more a matter of conflicting styles than a substantive confrontation with the real-world issues. But there is some attempt to be concrete. The symposium on Ivan Illich - with contributions from philosophers and social critics at the Penns- vania State University, where Illich has taught for several years - may suggest the old cliche of Old World vs. New World. Illich's fulminations against technology are often dismissed by Americans as old-world-style prophecy, while Illich seems largely unknown in his native Europe. But Albert Borgmann, born in Germany though now settled in the U.S., shows that this old dichotomy is difficult to maintain in our technological world. Borgmann's focus is on urgent technological problems that have become almost painfully evident in both Europe and America.