Proteome Research: New Frontiers in Functional Genomics

Proteome Research: New Frontiers in Functional Genomics PDF Author: Marc R. Wilkins
Publisher: Springer Science & Business Media
ISBN: 366203493X
Category : Science
Languages : en
Pages : 256

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Book Description
Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.

Proteome Research: New Frontiers in Functional Genomics

Proteome Research: New Frontiers in Functional Genomics PDF Author: Marc R. Wilkins
Publisher: Springer Science & Business Media
ISBN: 366203493X
Category : Science
Languages : en
Pages : 256

Get Book

Book Description
Recent advances in two-dimensional electrophoresis, protein microanalysis and bioinformatics have made the large-scale, systematic analysis of proteins and their post-translational modifications from any tissue or organism possible. This approach has acquired the name "Proteome Research", and can be considered as the core of functional genomics. The results of proteome analysis show which genes are expressed, how the protein products are modified, and how they interact, making proteome research of fundamental importance for the biologist, clinician, and pharmaceutical industry.

Proteome Research

Proteome Research PDF Author: Marc R. Wilkins
Publisher: Springer Science & Business Media
ISBN: 9783540627531
Category : Medical
Languages : en
Pages : 270

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Book Description
Introduction to the proteome (K. L. Williams, D. F. Hochstrasser). Two-dimensional electrophoresis: the state of the art and future directions (B. R. Herbert, J.-C. Sanchez, L. Bini). large-scale comparative protein modeling ( M. C. Peitsch, N. Guex); Clinical and biomedical applications of proteomics (D. F. Hochstrasser). Biological applications of proteomics (K. L. Williams, V. Pallini). Conclusions (D. F. Hochstrasser, L. Williams). Index.

Proteomics in Functional Genomics

Proteomics in Functional Genomics PDF Author: P. Jolles
Publisher: Birkhäuser
ISBN: 3034884583
Category : Science
Languages : en
Pages : 240

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Book Description
A wealth of information has accumulated over the last few years on the human genome. The new insights have completely changed the focus of protein analysis. It is no longer time-consuming analysis of unknown products, but rather selective identifications of individual forms, modifications and processings, and overall analysis of global protein outputs from cells and tissues in health and disease. This book gears to the rising need of sensitive, accurate, and fast separation and identification techniques in proteomics. It discusses current methodologies of modern protein analysis, from isolation and sample preparation, over analysis and identification, to final characterization. Several evaluations concentrate on the now productive approaches of two-dimensional gel electrophoresis and mass spectrometry, but alternative methods and further perspectives are also outlined. The book includes an overlook over current databases to connect protein analysis data with all available information,...

Functional Genomics and Proteomics

Functional Genomics and Proteomics PDF Author: Charles Malkoff
Publisher:
ISBN: 9781682861226
Category : Science
Languages : en
Pages : 0

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Book Description
Functional genomics and proteomics play a crucial role in analysing available genetic data and gathering key information for further use. The book emphasizes on the dynamic aspects of genomics and proteomics such as regulation of genes, transcription, translation and protein-protein interactions, large scale protein structures, etc. Researches and case-studies included in this book attempt to provide methods, models and techniques to analyze and gather information from large pool of available genomic data of various organisms. This book provides a detailed explanation on structure determination and structural genomics. Students and researchers will find this book beneficial.

Genomics and Proteomics

Genomics and Proteomics PDF Author: Sándor Suhai
Publisher: Springer Science & Business Media
ISBN: 0306468239
Category : Science
Languages : en
Pages : 246

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Book Description
Genome research will certainly be one of the most important and exciting sci- tific disciplines of the 21st century. Deciphering the structure of the human genome, as well as that of several model organisms, is the key to our understanding how genes fu- tion in health and disease. With the combined development of innovativetools, resources, scientific know-how, and an overall functional genomic strategy, the origins of human and other organisms’geneticdiseases can be traced. Scientificresearch groups and dev- opmental departments of several major pharmaceutical and biotechnological companies are using new, innovative strategies to unravel how genes function, elucidating the gene protein product, understanding how genes interact with others-both in health and in the disease state. Presently, the impact of the applications of genome research on our society in medicine, agriculture and nutrition will be comparable only to that of communication technologies. In fact, computational methods, including networking, have been playing a substantial role even in genomics and proteomics from the beginning. We can observe, however, a fundamental change of the paradigm in life sciences these days: research focused until now mostly on the study of single processes related to a few genes or gene products, but due to technical developments of the last years we can now potentially identify and analyze all genes and gene products of an organism and clarify their role in the network of lifeprocesses.

Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods PDF Author: Debasis Bagchi
Publisher: John Wiley & Sons
ISBN: 1118930428
Category : Technology & Engineering
Languages : en
Pages : 685

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Book Description
Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.

蛋白质与蛋白质组学实验指南

蛋白质与蛋白质组学实验指南 PDF Author: Richard J. Simpson
Publisher:
ISBN: 9787030119124
Category : Proteins
Languages : zh-CN
Pages : 926

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Book Description
本书提供了一系列可操作性强、行之有效的实验方案对蛋白质进行分离、鉴定、定量及功能分析,也有适于分析蛋白质结构包括电泳及色谱制备分析的方法,以及蛋白质芯片和生物信息学的相关内容。

Genomics and Proteomics in Nutrition

Genomics and Proteomics in Nutrition PDF Author: Carolyn D. Berdanier
Publisher: CRC Press
ISBN: 020302592X
Category : Medical
Languages : en
Pages : 525

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Book Description
With contributions from 66 world-renowned authorities on the subject, Genomics And Proteomics In Nutrition focuses on the effect of genetic expression on protein production, establishing links between gene expression and nutrition, the influence of micro- and macronutrients on cellular homeostasis, and the relationship between diet, genetic

Functional Genomics and Proteomics in the Clinical Neurosciences

Functional Genomics and Proteomics in the Clinical Neurosciences PDF Author: Scott E. Hemby
Publisher: Elsevier
ISBN: 0080465633
Category : Science
Languages : en
Pages : 329

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Book Description
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses. * Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry* Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies* Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques

Concepts and Techniques in Genomics and Proteomics

Concepts and Techniques in Genomics and Proteomics PDF Author: N Saraswathy
Publisher: Elsevier
ISBN: 1908818050
Category : Science
Languages : en
Pages : 271

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Book Description
Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references. Provides definitions for key concepts Case studies are included to illustrate ideas Important points to remember are noted