Author: Aitziber L. Cortajarena
Publisher: Springer
ISBN: 3319391968
Category : Science
Languages : en
Pages : 286
Book Description
This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.
Protein-based Engineered Nanostructures
Author: Aitziber L. Cortajarena
Publisher: Springer
ISBN: 3319391968
Category : Science
Languages : en
Pages : 286
Book Description
This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.
Publisher: Springer
ISBN: 3319391968
Category : Science
Languages : en
Pages : 286
Book Description
This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.
Nanostructures for the Engineering of Cells, Tissues and Organs
Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
ISBN: 0128136669
Category : Science
Languages : en
Pages : 631
Book Description
Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. - Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules - Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration - Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine
Publisher: William Andrew
ISBN: 0128136669
Category : Science
Languages : en
Pages : 631
Book Description
Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. - Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules - Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration - Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine
Protein Self-Assembly
Author: Jennifer J. McManus
Publisher: Humana
ISBN: 9781493996803
Category : Science
Languages : en
Pages : 266
Book Description
This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Publisher: Humana
ISBN: 9781493996803
Category : Science
Languages : en
Pages : 266
Book Description
This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
Engineered Nanostructures for Therapeutics and Biomedical Applications
Author: Ajeet Kumar Kaushik
Publisher: Woodhead Publishing
ISBN: 0128232218
Category : Technology & Engineering
Languages : en
Pages : 345
Book Description
Engineered Nanostructures for Therapeutics and Biomedical Applications offers a single reference for a diverse biomedical readership to learn about the application of nanotechnology in biomedicine and biomedical engineering, from past developments to current research and future prospects. This book sets out a broad selection of biomedical and therapeutic applications for nanostructures, including bioimaging, nanorobotics, orthopedics, and tissue engineering, offering a useful, multidisciplinary approach. Each chapter discusses challenges faced in each discipline, including limiting factors, biocompatibility, and toxicity, thus enabling the reader to make informed decisions in their research.This book is a comprehensive, broad overview of the role and significance of nanomaterials and their composites that also includes discussions of key aspects in the field of biomedicine. It will be of significant interest to academics and researchers in materials science and engineering, biomedicine and biomedical engineering, chemical engineering, pharmaceutics, bioimaging, and nanorobotics. - Provides a broad overview of the many applications of nanomaterials and nanotechnology in biomedicine and engineering - Offers a multidisciplinary approach that will appeal to a diverse readership, including those in biomedical engineering, materials science, biomedicine, and pharmaceutics - Includes challenges faced and limiting factors for each application, allowing readers to make an informed decision when using nanomaterials in their research
Publisher: Woodhead Publishing
ISBN: 0128232218
Category : Technology & Engineering
Languages : en
Pages : 345
Book Description
Engineered Nanostructures for Therapeutics and Biomedical Applications offers a single reference for a diverse biomedical readership to learn about the application of nanotechnology in biomedicine and biomedical engineering, from past developments to current research and future prospects. This book sets out a broad selection of biomedical and therapeutic applications for nanostructures, including bioimaging, nanorobotics, orthopedics, and tissue engineering, offering a useful, multidisciplinary approach. Each chapter discusses challenges faced in each discipline, including limiting factors, biocompatibility, and toxicity, thus enabling the reader to make informed decisions in their research.This book is a comprehensive, broad overview of the role and significance of nanomaterials and their composites that also includes discussions of key aspects in the field of biomedicine. It will be of significant interest to academics and researchers in materials science and engineering, biomedicine and biomedical engineering, chemical engineering, pharmaceutics, bioimaging, and nanorobotics. - Provides a broad overview of the many applications of nanomaterials and nanotechnology in biomedicine and engineering - Offers a multidisciplinary approach that will appeal to a diverse readership, including those in biomedical engineering, materials science, biomedicine, and pharmaceutics - Includes challenges faced and limiting factors for each application, allowing readers to make an informed decision when using nanomaterials in their research
Functionalized Nanomaterials II
Author: Vineet Kumar
Publisher: CRC Press
ISBN: 1351021370
Category : Medical
Languages : en
Pages : 273
Book Description
The functionalization of nanomaterials provides them with some unique properties, making the same nanomaterial amenable for various applications by simply manipulating functional components. However, functionalized nanomaterials also face some challenges, along with some encouraging new applications in the future. This book provides a detailed account of applications of the functionalization of nanomaterials. This book can serve as a reference book for scientific investigators, including doctoral and post-doctoral scholars and undergraduate and graduate students, in context with the scope of applications of functionalized nanomaterials. It also highlights recent advances, challenges, and opportunities in the application of nanomaterials. This book will provide critical and comparative data for nanotechnologists. It may also be beneficial for multidisciplinary researchers, industry personnel, journalists, policy makers, and the common public to understand the scope of functionalized nanomaterials in detail and in depth. Features: This book covers various applications of functionalized nanomaterials. It discusses recent global research trends and future applications of functionalized nanomaterials. It highlights the need for more rigorous regulatory frameworks for the safe use of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.
Publisher: CRC Press
ISBN: 1351021370
Category : Medical
Languages : en
Pages : 273
Book Description
The functionalization of nanomaterials provides them with some unique properties, making the same nanomaterial amenable for various applications by simply manipulating functional components. However, functionalized nanomaterials also face some challenges, along with some encouraging new applications in the future. This book provides a detailed account of applications of the functionalization of nanomaterials. This book can serve as a reference book for scientific investigators, including doctoral and post-doctoral scholars and undergraduate and graduate students, in context with the scope of applications of functionalized nanomaterials. It also highlights recent advances, challenges, and opportunities in the application of nanomaterials. This book will provide critical and comparative data for nanotechnologists. It may also be beneficial for multidisciplinary researchers, industry personnel, journalists, policy makers, and the common public to understand the scope of functionalized nanomaterials in detail and in depth. Features: This book covers various applications of functionalized nanomaterials. It discusses recent global research trends and future applications of functionalized nanomaterials. It highlights the need for more rigorous regulatory frameworks for the safe use of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.
Tissue Engineering
Author: Rajesh K. Kesharwani
Publisher: CRC Press
ISBN: 1000400956
Category : Medical
Languages : en
Pages : 354
Book Description
This new volume on applications and advances in tissue engineering presents significant, state-of-the-art developments in this exciting area of research. It highlights some of the most important applied research on the applications of tissue engineering along with its different components, specifically different types of biomaterials. It looks at the various issues involved in tissue engineering, including smart polymeric biomaterials, gene therapy, tissue engineering in reconstruction and regeneration of visceral organs, skin tissue engineering, bone and muscle regeneration, and applications in tropical medicines. Covering a wide range of issues in tissue engineering, the volume Provides an overview of the efficacy of the different biomaterials employed in tissue engineering (such as skin regeneration, nerve regeneration, artificial blood vessels, bone regeneration). Looks at smart polymeric biomaterials in tissue engineering Discusses the hybrid approach of tissue engineering in conjunction with gene therapy Explores using tissue engineering in the management of tropical diseases Considers various skin tissue engineering applications, including wound healing methods, skin substitutes and other materials Reports on the use of various biomaterials in bone and muscle regeneration Describes the use of tissue engineering in reconstruction and regeneration of visceral organs Covers polysaccharides and proteins-based hydrogels for tissue engineering applications Providing an abundance of advanced research and information, Tissue Engineering: Applications and Advancements will be a valuable resource for medical researchers, pharmaceutical manufacturers, healthcare personnel, and academicians.
Publisher: CRC Press
ISBN: 1000400956
Category : Medical
Languages : en
Pages : 354
Book Description
This new volume on applications and advances in tissue engineering presents significant, state-of-the-art developments in this exciting area of research. It highlights some of the most important applied research on the applications of tissue engineering along with its different components, specifically different types of biomaterials. It looks at the various issues involved in tissue engineering, including smart polymeric biomaterials, gene therapy, tissue engineering in reconstruction and regeneration of visceral organs, skin tissue engineering, bone and muscle regeneration, and applications in tropical medicines. Covering a wide range of issues in tissue engineering, the volume Provides an overview of the efficacy of the different biomaterials employed in tissue engineering (such as skin regeneration, nerve regeneration, artificial blood vessels, bone regeneration). Looks at smart polymeric biomaterials in tissue engineering Discusses the hybrid approach of tissue engineering in conjunction with gene therapy Explores using tissue engineering in the management of tropical diseases Considers various skin tissue engineering applications, including wound healing methods, skin substitutes and other materials Reports on the use of various biomaterials in bone and muscle regeneration Describes the use of tissue engineering in reconstruction and regeneration of visceral organs Covers polysaccharides and proteins-based hydrogels for tissue engineering applications Providing an abundance of advanced research and information, Tissue Engineering: Applications and Advancements will be a valuable resource for medical researchers, pharmaceutical manufacturers, healthcare personnel, and academicians.
Healthy Past 100
Author: Steven M. Teagarden DC
Publisher: BookLocker.com, Inc.
ISBN:
Category : Health & Fitness
Languages : en
Pages : 990
Book Description
Healthy Past 100 was written explicitly for those longing to be extraordinarily healthy—even past their 100th birthday. This breakthrough book is based on thousands of cutting-edge science articles identifying the causes of optimal health vs sickness and disease. Healthy Past 100 puts a wealth of cutting-edge, science-based healthcare information at your fingertips, empowering you to make the healthiest choices for you and your family. Healthy Past 100 is several books in one, and it also contains a mouthwatering keto cookbook that's exclusively based on the most nourishing ingredients you can consume. This life-changing book is based on the Short List, i.e., a distillation of the core factors involved in being healthy past 100. The Short List includes: The Metabolic Masterplan Diet: the Metabolic Masterplan Diet may be the world's most advanced ketogenic diet. Nothing improves your health as much as following this research-based, anti-inflammatory, gut-healing ketogenic diet. Nutrition and Supplements: providing your cells with all the nutrients they require to function optimally is key to a long, healthy life. Healthy Past 100 shows you exactly which nutrients you need and which ones to supplement with. Metabolism: carbohydrates and sugar damage your metabolism (the process of creating energy in your cells), causing serious health issues. Healthy Past 100 teaches you to heal and optimize your metabolism, and which tests to rely on to know—not guess—that your metabolism is as healthy as can be. Chronic Inflammation: this widespread health issue underlies all diseases, and must be healed to experience optimal health. Healthy Past 100 rids you of chronic inflammation—now and forever—paving the way to lasting health. Gut Health: most humans deal with significant gut issues. Fortunately, Healthy Past 100's innovative gut healing method leads to lifelong optimized gut health. Psychology: psychology is how you think, feel, act, behave and respond to life's circumstances. Healthy Past 100 provides the tools to heal and optimize your psychology, which is foundational to a healthy, fulfilling life. Thyroid Physiology: inefficient thyroid physiology impairs your body and mind, zaps your energy and causes many diseases. Healthy Past 100 explains how thyroid physiology works, how to heal it, and the tests determining if it's in tip-top shape. Exercise: crucial to your health and well-being, exercise must be performed regularly. Healthy Past 100 teaches you which exercises help you become healthy past 100. Detoxification: humans are routinely exposed to dangerous heavy metal toxins. Healthy Past 100 shows you how to rid these harmful metals from your body and minimize your exposure to them in the future. Oxidative Stress: oxidative stress is a primary cause of aging, sickness, disease and death. It has many causes, including carbohydrates, sugar, poor nutrition and impaired gut health. Healthy Past 100 helps you optimize oxidative stress where it matters most: within the mitochondria in your cells. Spiritual/Religious Life: extraordinary health stems from optimal physical, psychological and spiritual well-being. It's just as important to focus on your spiritual fitness as it is to heal your physical body, and Healthy Past 100 helps you do both. This pioneering book has been written to help you experience extraordinary health past your 100th birthday. If you're ready to be healthy past 100, this is the book you've been waiting for!
Publisher: BookLocker.com, Inc.
ISBN:
Category : Health & Fitness
Languages : en
Pages : 990
Book Description
Healthy Past 100 was written explicitly for those longing to be extraordinarily healthy—even past their 100th birthday. This breakthrough book is based on thousands of cutting-edge science articles identifying the causes of optimal health vs sickness and disease. Healthy Past 100 puts a wealth of cutting-edge, science-based healthcare information at your fingertips, empowering you to make the healthiest choices for you and your family. Healthy Past 100 is several books in one, and it also contains a mouthwatering keto cookbook that's exclusively based on the most nourishing ingredients you can consume. This life-changing book is based on the Short List, i.e., a distillation of the core factors involved in being healthy past 100. The Short List includes: The Metabolic Masterplan Diet: the Metabolic Masterplan Diet may be the world's most advanced ketogenic diet. Nothing improves your health as much as following this research-based, anti-inflammatory, gut-healing ketogenic diet. Nutrition and Supplements: providing your cells with all the nutrients they require to function optimally is key to a long, healthy life. Healthy Past 100 shows you exactly which nutrients you need and which ones to supplement with. Metabolism: carbohydrates and sugar damage your metabolism (the process of creating energy in your cells), causing serious health issues. Healthy Past 100 teaches you to heal and optimize your metabolism, and which tests to rely on to know—not guess—that your metabolism is as healthy as can be. Chronic Inflammation: this widespread health issue underlies all diseases, and must be healed to experience optimal health. Healthy Past 100 rids you of chronic inflammation—now and forever—paving the way to lasting health. Gut Health: most humans deal with significant gut issues. Fortunately, Healthy Past 100's innovative gut healing method leads to lifelong optimized gut health. Psychology: psychology is how you think, feel, act, behave and respond to life's circumstances. Healthy Past 100 provides the tools to heal and optimize your psychology, which is foundational to a healthy, fulfilling life. Thyroid Physiology: inefficient thyroid physiology impairs your body and mind, zaps your energy and causes many diseases. Healthy Past 100 explains how thyroid physiology works, how to heal it, and the tests determining if it's in tip-top shape. Exercise: crucial to your health and well-being, exercise must be performed regularly. Healthy Past 100 teaches you which exercises help you become healthy past 100. Detoxification: humans are routinely exposed to dangerous heavy metal toxins. Healthy Past 100 shows you how to rid these harmful metals from your body and minimize your exposure to them in the future. Oxidative Stress: oxidative stress is a primary cause of aging, sickness, disease and death. It has many causes, including carbohydrates, sugar, poor nutrition and impaired gut health. Healthy Past 100 helps you optimize oxidative stress where it matters most: within the mitochondria in your cells. Spiritual/Religious Life: extraordinary health stems from optimal physical, psychological and spiritual well-being. It's just as important to focus on your spiritual fitness as it is to heal your physical body, and Healthy Past 100 helps you do both. This pioneering book has been written to help you experience extraordinary health past your 100th birthday. If you're ready to be healthy past 100, this is the book you've been waiting for!
Nanotechnologies in Preventive and Regenerative Medicine
Author: Vuk Uskokovic
Publisher: Elsevier
ISBN: 0323480640
Category : Medical
Languages : en
Pages : 618
Book Description
Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments
Publisher: Elsevier
ISBN: 0323480640
Category : Medical
Languages : en
Pages : 618
Book Description
Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments
Basic Protocols in Encapsulation of Food Ingredients
Author: Andrea Gomez-Zavaglia
Publisher: Springer Nature
ISBN: 1071616498
Category : Technology & Engineering
Languages : en
Pages : 203
Book Description
This volume provides a comprehensive introduction into methods and procedures on encapsulation of sensitive food nucleus. Chapters guide readers through different strategies to encapsulate bioactive compounds and cells. Additionally, chapters will detail methods on three major issues; the nucleus to be encapsulated, the carrier material, and the encapsulation technique. Authoritative and cutting-edge, Basic Protocols in Encapsulation of Food Ingredients aims to give guidance on encapsulation techniques and an understanding on tools, materials, and supplies to implement innovative approaches.
Publisher: Springer Nature
ISBN: 1071616498
Category : Technology & Engineering
Languages : en
Pages : 203
Book Description
This volume provides a comprehensive introduction into methods and procedures on encapsulation of sensitive food nucleus. Chapters guide readers through different strategies to encapsulate bioactive compounds and cells. Additionally, chapters will detail methods on three major issues; the nucleus to be encapsulated, the carrier material, and the encapsulation technique. Authoritative and cutting-edge, Basic Protocols in Encapsulation of Food Ingredients aims to give guidance on encapsulation techniques and an understanding on tools, materials, and supplies to implement innovative approaches.
Handbook of Immunological Properties of Engineered Nanomaterials
Author: Marina Dobrovolskaia
Publisher: World Scientific
ISBN: 9814390259
Category : Medical
Languages : en
Pages : 721
Book Description
The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.
Publisher: World Scientific
ISBN: 9814390259
Category : Medical
Languages : en
Pages : 721
Book Description
The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.