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Author: P. K. Moore
Publisher: CUP Archive
ISBN: 9780521278270
Category : Science
Languages : en
Pages : 276
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Book Description
Prostanoids are a group of fat-soluble compounds synthesised by almost every cell in the human body, and they are essential to the proper functioning of the organs. Interruption to the constant rate of formation and release of prostanoids may cause life-threatening conditions to develop, for example a deficiency may exacerbate or cause strokes, heart disease, diabetes and an excess is implicated in arthritis. The interest in the structure and functions of prostanoids is great and much research effort has been spent on elucidating facts about them. This book makes explicit the present knowledge on the subject, and emphasises the pharmacology, physiology and relevance to clinical conditions. It offers those studying pharmacology and physiology, particularly in preclinical medical courses, an up-to-date summary of this exciting group of substances.
Author: P. K. Moore
Publisher: CUP Archive
ISBN: 9780521278270
Category : Science
Languages : en
Pages : 276
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Book Description
Prostanoids are a group of fat-soluble compounds synthesised by almost every cell in the human body, and they are essential to the proper functioning of the organs. Interruption to the constant rate of formation and release of prostanoids may cause life-threatening conditions to develop, for example a deficiency may exacerbate or cause strokes, heart disease, diabetes and an excess is implicated in arthritis. The interest in the structure and functions of prostanoids is great and much research effort has been spent on elucidating facts about them. This book makes explicit the present knowledge on the subject, and emphasises the pharmacology, physiology and relevance to clinical conditions. It offers those studying pharmacology and physiology, particularly in preclinical medical courses, an up-to-date summary of this exciting group of substances.
Author: Stanley M. Roberts
Publisher: Elsevier
ISBN: 1483146030
Category : Science
Languages : en
Pages : 420
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Book Description
Chemistry, Biochemistry, and Pharmacological Activity of Prostanoids contains the proceedings of a symposium on the Chemistry and Biochemistry of Prostanoids held at the University of Salford, England on July 10-14, 1978. Separating 29 papers of the symposium as chapters, this book begins with a description of prostanoids in health and disease and recent developments in the synthesis of antisecretory prostaglandins. Other topics discuss synthesis of some novel 11-deoxyprostaglandins; bicycles, tricycles and prostaglandin synthesis; chemical and biological studies on new prostanoids; and isolation and characterization of enzymes involved in prostaglandin biosynthesis. Structure activity relationships of prostaglandins and a biochemical background of caloric restriction therapy of obesity are also explained.
Author: G. Hornstra
Publisher: Springer Science & Business Media
ISBN: 9400975767
Category : Medical
Languages : en
Pages : 253
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Book Description
Knowledge of mechanisms involved in the pathogenesis of occlusive arterial dis eases is fundamental for the design of prevention and treatment. A series of studies based on in vitro investigations, the experimental animal and the human being have slowly increased our understanding of cardiovascular diseases and unveiled their secrets to us. Over the last 60 years it has been generally assumed that dietary fats and lipids and the occurrence of atherosclerosis are closely related. Yet, even if epidemiological studies clearly indicate the existence of an association between the amount of composition of dietary lipids and morbidity and mortality of cardio vascular disease, our basic knowledge on cause and effect is still hidden in a cloud of uncertainty. The present book discusses the relation between dietary lipids and arterial throm bosis, which latter process has been observed in the coronary arteries in up to 90% of subjects with acute myocardial infaction. In this volume Dr. Hornstra, who has occupied himself with thrombosis research with never-failing enthusiasm, great skill and critical approach for the last fifteen years, tries to establish possible links between lipid metabolism and thrombosis. His literature studies are comprehensive and his investigations are impressive in that they give a new dimension and a new methodology to research of lipids and thrombosis.
Author: B. Samuelson
Publisher: Springer Science & Business Media
ISBN: 1468479385
Category : Medical
Languages : en
Pages : 258
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Book Description
This volume, the sixth in the series "The Prostaglandin System" assembles most of the lecture notes from the International School of Pharmacology on "Prostanoids and Drugs" that took place in Erice, Sicily, at the "Ettore Majorana Center for Scientific Culture" on Sept 5-15, 1989. The course, which was a NATO Advanced Study Institute, comprised detailed discussion of basic metabolic pathways of arachidonic acid as well as their location in the everyday practice of clinical medicine. The current status of our knowledge on drugs affecting prostanoid metabolic pathways, and/or their functinal effects, together with the use of prostanoids as drugs, has been reviewed in depth by distinguished experts. In certain instances a few chapters might overlap with others to present divergent viewpoints of authors, for a better assessment of the complexity of eicosanoid biology. It is likely that as our knowledge of prostanoids in different diseases increases, new diseases may also be targets for drugs related to these lipid mediators. We hope that this boo~will encourage basic scientists and clinicians to pursue additional biomedical investigations along these lines of inquiry. Moreover we would like to take this opportunity to express our gratitude to all the invited speakers not only for their important contributions before and during the course but also for their ability in creating an atmosphere in which all questions were legitimate and all lines of investigations were encouraged.
Author: Paolo Gresele
Publisher: Springer
ISBN: 3319474626
Category : Medical
Languages : en
Pages : 1402
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Book Description
This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
Author: Peter Curtis-Prior
Publisher: John Wiley & Sons
ISBN: 047002061X
Category : Medical
Languages : de
Pages : 654
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Book Description
This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
Author: Valéria Kecskeméti
Publisher: Elsevier
ISBN: 1483147916
Category : Medical
Languages : en
Pages : 184
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Book Description
Prostanoids, Volume VI, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. Prostaglandin research is an exciting and rapidly developing field in chemical and biological sciences. It is the recently discovered prostacyclin that has brought about a breakthrough in prostaglandin research giving new impetus to clinical investigation. This volume contains 22 papers read at the ""Prostanoids Symposium"" by participants from eight different countries. Numerous new data concerning the synthesis of prostacyclin and different stable prostacyclin analogues are presented. Besides the problems of synthetic chemistry, data are given about the pharmacological properties of these prostacyclin analogues, analyzing their effects on heat and smooth muscles. Several papers dealing with the involvement of different pharmacologically active agents and hormones in the biosynthesis of prostaglandins emphasize the important role of prostanoids in various pathophysiological processes and diseases. The clinical use of prostacyclin, having already earned an outstanding position in medicine, is stressed.
Author: Robert Wesley Coatney
Publisher:
ISBN:
Category : Digestion
Languages : en
Pages : 344
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Book Description
Author: Frederick W. Alt
Publisher: Academic Press
ISBN: 0123946387
Category : Medical
Languages : en
Pages : 243
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Book Description
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities Informs and updates on all the latest developments in the field
Author: Magyar Farmakológiai Társaság. Congress
Publisher: Pergamon
ISBN: 9780080263915
Category : Prostacyclin
Languages : en
Pages : 175
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Book Description
