Prospective Longevity

Prospective Longevity PDF Author: Warren C. Sanderson
Publisher: Harvard University Press
ISBN: 0674975618
Category : Social Science
Languages : en
Pages : 273

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Book Description
From two leading experts, a revolutionary new way to think about and measure aging. Aging is a complex phenomenon. We usually think of chronological age as a benchmark, but it is actually a backward way of defining lifespan. It tells us how long we’ve lived so far, but what about the rest of our lives? In this pathbreaking book, Warren C. Sanderson and Sergei Scherbov provide a new way to measure individual and population aging. Instead of counting how many years we’ve lived, we should think about the number of years we have left, our “prospective age.” Two people who share the same chronological age probably have different prospective ages, because one will outlive the other. Combining their forward-thinking measure of our remaining years with other health metrics, Sanderson and Scherbov show how we can generate better demographic estimates, which inform better policies. Measuring prospective age helps make sense of observed patterns of survival, reorients understanding of health in old age, and clarifies the burden of old-age dependency. The metric also brings valuable data to debates over equitable intergenerational pensions. Sanderson and Scherbov’s pioneering model has already been adopted by the United Nations. Prospective Longevity offers us all an opportunity to rethink aging, so that we can make the right choices for our societal and economic health.

Prospective Longevity

Prospective Longevity PDF Author: Warren C. Sanderson
Publisher: Harvard University Press
ISBN: 0674975618
Category : Social Science
Languages : en
Pages : 273

Get Book Here

Book Description
From two leading experts, a revolutionary new way to think about and measure aging. Aging is a complex phenomenon. We usually think of chronological age as a benchmark, but it is actually a backward way of defining lifespan. It tells us how long we’ve lived so far, but what about the rest of our lives? In this pathbreaking book, Warren C. Sanderson and Sergei Scherbov provide a new way to measure individual and population aging. Instead of counting how many years we’ve lived, we should think about the number of years we have left, our “prospective age.” Two people who share the same chronological age probably have different prospective ages, because one will outlive the other. Combining their forward-thinking measure of our remaining years with other health metrics, Sanderson and Scherbov show how we can generate better demographic estimates, which inform better policies. Measuring prospective age helps make sense of observed patterns of survival, reorients understanding of health in old age, and clarifies the burden of old-age dependency. The metric also brings valuable data to debates over equitable intergenerational pensions. Sanderson and Scherbov’s pioneering model has already been adopted by the United Nations. Prospective Longevity offers us all an opportunity to rethink aging, so that we can make the right choices for our societal and economic health.

The Longevity Seekers

The Longevity Seekers PDF Author: Ted Anton
Publisher: University of Chicago Press
ISBN: 0226020959
Category : Health & Fitness
Languages : en
Pages : 240

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Book Description
“[A] beautifully told story of twenty-first-century researchers in pursuit of the secrets of longevity . . . a book both engaging and illuminating.” —Deborah Blum, Pulitzer Prize-winning author People have searched for the fountain of youth everywhere from Bimini to St. Augustine. But for a steadfast group of scientists, the secret to a long life lies elsewhere: in the lowly lab worm. By suppressing the function of just a few key genes, these scientists were able to lengthen worms’ lifespans up to tenfold, while also controlling the onset of many of the physical problems that beset old age. As the global population ages, the potential impact of this discovery on society is vast—as is the potential for profit. With The Longevity Seekers, science writer Ted Anton takes readers inside this tale that began with worms and branched out to snare innovative minds from California to Crete, investments from big biotech, and endorsements from TV personalities like Oprah and Dr. Oz. Some of the research was remarkable, such as the discovery of an enzyme in humans that stops cells from aging. And some—like an oft-cited study touting the compound resveratrol, found in red wine—proved highly controversial, igniting a science war over truth, credit, and potential profit. As the pace of discovery accelerated, so too did powerful personal rivalries and public fascination, driven by the hope that a longer, healthier life was right around the corner. Anton has spent years interviewing and working with the scientists at the frontier of longevity science, and this book offers a behind-the-scenes look at the state-of-the-art research and the impact it might have on global public health, society, and even our friends and family

Longevity, Senescence, and the Genome

Longevity, Senescence, and the Genome PDF Author: Caleb E. Finch
Publisher: University of Chicago Press
ISBN: 9780226248899
Category : Health & Fitness
Languages : en
Pages : 948

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Book Description
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.

Biomarkers of Human Longevity

Biomarkers of Human Longevity PDF Author: Dmitry Kaminskiy
Publisher:
ISBN: 9781916391772
Category : Business & Economics
Languages : en
Pages : 412

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Book Description
There is perhaps no other single technology or industry subsector, with the exception of AI, that has more potential to accelerate the realization of real-world impacts in Longevity across the full scope of its sectors and domains - industry, policy, investment, entrepreneurship, policy, and governance - than Biomarkers of Human Longevity. Given the unique confluence of Biomarkers of Human Longevity's disruptive impact and accelerative potential, on the one hand, and the high degree of disharmonization in terms of what they are and how they could and should be used, on the other hand, it is clear to me that there is a pressing unmet need for the production of a dedicated book that takes Biomarkers of Longevity as its central concern and major fulcrum, identifying the true potential that this technology has to increase individual and national Health-Adjusted Life Expectancy (HALE) and Quality-Adjusted Life Expectancy (QALY), optimize strategic decision-making for start-ups and corporations, de-risk investment, provide for the first time a tangible framework for company valuation, due diligence based on human validation, enable reliable forecasting clinical outcomes, serve as an effective platform for safe self-experimentation and personalized therapeutic fine-tuning, and pave the way for a much more tangible, stable and scalable Global Longevity Industry, where Longevity's socially-inclusive humanitarian impact is maximized and its potential ethical and socioeconomic concerns are neutralized. Deep Knowledge Group and its Longevity-focused subsidiaries and affiliates, including its analytical subsidiary Aging Analytics Agency, its specialized investment arm Longevity.Capital, its portfolio companies Longevity Banking Card and Longevity Financial Advisors and the international non-profit consortium Longevity.International, have prioritized the pressing need and the extreme potential of Biomarkers of Human Longevity (and integrated them in various ways into its overall scope of activities and strategic agenda) for several years now, and are expertly positioned to provide a tangible understanding of the major challenges and opportunities to be faced within this domain, and how they can be applied by individuals, institutions and even entire governments in order to achieve their maximum benefits while neutralizing potential pitfalls and issues.

Developments in Demographic Forecasting

Developments in Demographic Forecasting PDF Author: Stefano Mazzuco
Publisher: Springer Nature
ISBN: 3030424723
Category : Social Science
Languages : en
Pages : 261

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Book Description
This open access book presents new developments in the field of demographic forecasting, covering both mortality, fertility and migration. For each component emerging methods to forecast them are presented. Moreover, instruments for forecasting evaluation are provided. Bayesian models, nonparametric models, cohort approaches, elicitation of expert opinion, evaluation of probabilistic forecasts are some of the topics covered in the book. In addition, the book is accompanied by complementary material on the web allowing readers to practice with some of the ideas exposed in the book. Readers are encouraged to use this material to apply the new methods to their own data. The book is an important read for demographers, applied statisticians, as well as other social scientists interested or active in the field of population forecasting. Professional population forecasters in statistical agencies will find useful new ideas in various chapters.

Explaining Divergent Levels of Longevity in High-Income Countries

Explaining Divergent Levels of Longevity in High-Income Countries PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309217105
Category : Social Science
Languages : en
Pages : 200

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Book Description
During the last 25 years, life expectancy at age 50 in the United States has been rising, but at a slower pace than in many other high-income countries, such as Japan and Australia. This difference is particularly notable given that the United States spends more on health care than any other nation. Concerned about this divergence, the National Institute on Aging asked the National Research Council to examine evidence on its possible causes. According to Explaining Divergent Levels of Longevity in High-Income Countries, the nation's history of heavy smoking is a major reason why lifespans in the United States fall short of those in many other high-income nations. Evidence suggests that current obesity levels play a substantial part as well. The book reports that lack of universal access to health care in the U.S. also has increased mortality and reduced life expectancy, though this is a less significant factor for those over age 65 because of Medicare access. For the main causes of death at older ages-cancer and cardiovascular disease-available indicators do not suggest that the U.S. health care system is failing to prevent deaths that would be averted elsewhere. In fact, cancer detection and survival appear to be better in the U.S. than in most other high-income nations, and survival rates following a heart attack also are favorable. Explaining Divergent Levels of Longevity in High-Income Countries identifies many gaps in research. For instance, while lung cancer deaths are a reliable marker of the damage from smoking, no clear-cut marker exists for obesity, physical inactivity, social integration, or other risks considered in this book. Moreover, evaluation of these risk factors is based on observational studies, which-unlike randomized controlled trials-are subject to many biases.

Biology of Longevity and Aging

Biology of Longevity and Aging PDF Author: Robert Arking
Publisher:
ISBN: 0199387966
Category : Family & Relationships
Languages : en
Pages : 721

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Book Description
An introductory text to the biology of aging and longevity, offering a thorough review of the field.

The Longevity Imperative

The Longevity Imperative PDF Author: Andrew J. Scott
Publisher: Basic Books
ISBN: 1541604512
Category : Political Science
Languages : en
Pages : 305

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Book Description
From a leading expert on longevity, an urgent call for individuals, institutions, and society to adapt to the reality of living longer lives Thanks to increases in life expectancy, we can now expect to live for a long time. Most of us would welcome an extra day in the week, so why do so many of us view the prospect of additional years with fear and skepticism? The reason is simple: society is not currently structured to support long lives. Rather than thinking in terms of the needs of a rising number of older people, we must instead support the young and middle-aged to prepare differently for the longer futures they can expect. The Longevity Imperative outlines the innovations needed to make the most of these longer lives: substantial changes to our health system, economy, and financial sector, as well as in how we manage our careers, health, finances, and relationships. Instead of seeing longevity as a problem, economist Andrew J. Scott challenges us to view it as an opportunity. This book charts a course to address the individual, social, political, economic, and cultural changes required so that all of us—regardless of age—can live lives that are not just longer but healthier, happier, and more productive.

New Methuselahs

New Methuselahs PDF Author: John K. Davis
Publisher: MIT Press
ISBN: 026255156X
Category : Science
Languages : en
Pages : 369

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Book Description
An examination of the ethical issues raised by the possibility of human life extension, including its desirability, unequal access, and the threat of overpopulation. Life extension—slowing or halting human aging—is now being taken seriously by many scientists. Although no techniques to slow human aging yet exist, researchers have successfully slowed aging in yeast, mice, and fruit flies, and have determined that humans share aging-related genes with these species. In New Methuselahs, John Davis offers a philosophical discussion of the ethical issues raised by the possibility of human life extension. Why consider these issues now, before human life extension is a reality? Davis points out that, even today, we are making policy and funding decisions about human life extension research that have ethical implications. With New Methuselahs, he provides a comprehensive guide to these issues, offering policy recommendations and a qualified defense of life extension. After an overview of the ethics and science of life extension, Davis considers such issues as the desirability of extended life; whether refusing extended life is a form of suicide; the Malthusian threat of overpopulation; equal access to life extension; and life extension and the right against harm. In the end, Davis sides neither with those who argue that there are no moral objections to life enhancement nor with those who argue that the moral objections are so strong that we should never develop it. Davis argues that life extension is, on balance, a good thing and that we should fund life extension research aggressively, and he proposes a feasible and just policy for preventing an overpopulation crisis.

The Longevity Dividend

The Longevity Dividend PDF Author: Satya Brink
Publisher: Springer Nature
ISBN: 3031353358
Category : Social Science
Languages : en
Pages : 232

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Book Description
This book offers global evidence about the increasing longevity, its consequences and its potential for societal benefits. Based on statistics, academic literature, policy initiatives and numerous country experiences, it explains the interconnected effects of a longer later life, lifelong learning and more productive societies. This larger picture shows how the future can be managed by making strategic choices today. Choosing the right policies allows gaining the maximum benefits from the longevity dividend for current and future generations. This book explains how investing in lifelong learning can enrich the longevity dividend. It gives valuable insights for policy advisors, decision makers, researchers, health professionals, practitioners, students of aging and late life educators.