Author: Jason Patrick Burke
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Progress Toward the Total Synthesis of the Symbioimine Family of Alkaloids
Author: Jason Patrick Burke
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Progress Toward a Total Synthesis of the Welwitindolinone Alkaloids
Author: Matthew Mark Weiss
Publisher:
ISBN:
Category :
Languages : en
Pages : 1242
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 1242
Book Description
Progress Toward a Total Synthesis of the Marine Alkaloid Perophoramidine
Author: Joshua Sacher
Publisher:
ISBN:
Category :
Languages : en
Pages : 69
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 69
Book Description
Progress Toward the Total Synthesis of Daphniphyllum Alkaloids
Author: Alberto Michael Lopez
Publisher:
ISBN:
Category : Chemistry, Organic
Languages : en
Pages : 308
Book Description
The Daphniphyllum alkaloids are polycyclic natural products isolated from evergreen trees and shrubs native to areas of Southeast Asia. Their structural complexity and biological activity has motived the synthetic community to devise unique strategies to access these molecules. An elegant biomimetic synthesis of methyl homodaphniphyllate by Heathcock and co-workers in 1992 was the first reported total synthesis of a Daphniphyllum alkaloid. In the years since that report, approximately 300 Daphniphyllum alkaloids have been isolated and reported. This recent flood of discovery has been met with an analogous upsurge of interest. Since 2011, 10 total syntheses and several partial syntheses of Daphniphyllum alkaloids have been reported. In our retrosynthetic analysis of calyciphylline A and daphnicyclidin-type alkaloids, we imagined that a N-centered radical tandem cyclization would rapidly build their tricyclic. Indeed, this key cyclization was achieved and we were compelled to pursue the total synthesis of the target molecules.
Publisher:
ISBN:
Category : Chemistry, Organic
Languages : en
Pages : 308
Book Description
The Daphniphyllum alkaloids are polycyclic natural products isolated from evergreen trees and shrubs native to areas of Southeast Asia. Their structural complexity and biological activity has motived the synthetic community to devise unique strategies to access these molecules. An elegant biomimetic synthesis of methyl homodaphniphyllate by Heathcock and co-workers in 1992 was the first reported total synthesis of a Daphniphyllum alkaloid. In the years since that report, approximately 300 Daphniphyllum alkaloids have been isolated and reported. This recent flood of discovery has been met with an analogous upsurge of interest. Since 2011, 10 total syntheses and several partial syntheses of Daphniphyllum alkaloids have been reported. In our retrosynthetic analysis of calyciphylline A and daphnicyclidin-type alkaloids, we imagined that a N-centered radical tandem cyclization would rapidly build their tricyclic. Indeed, this key cyclization was achieved and we were compelled to pursue the total synthesis of the target molecules.
Progress Toward an Asymmetric Total Synthesis of a Stemona Alkaloid, Tuberostemoninol
Author: Xiangna Jia
Publisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 366
Book Description
Publisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 366
Book Description
Progress Towards Enantioselective Total Synthesis of the Bisbenzyltetrahydroisoquinoline Alkaloid ( - )- Cycleanine and a New Approach to the Syntheses of Some Isoquinolones
Author: Jianwen Cui
Publisher:
ISBN:
Category : Tetrahydroisoquinolines
Languages : en
Pages : 270
Book Description
Publisher:
ISBN:
Category : Tetrahydroisoquinolines
Languages : en
Pages : 270
Book Description
Progress Towards the Total Synthesis of the Antitumor Alkaloid Manzamine A.
Author: Dennis de Oliveira Imbroisi
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Progress Towards the Total Synthesis of Pentacyclic Guanidinium Alkaloids
Author: Yasamin Moazami
Publisher:
ISBN:
Category :
Languages : en
Pages : 195
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 195
Book Description
Further Progress Towards Enantioselective Total Synthesis of the Bisbenzyltetrahydroisoquinoline Alkaloid ( - )-cycleanine
Author: Ningzhang Zhou
Publisher:
ISBN:
Category : Tetrahydroisoquinolines
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category : Tetrahydroisoquinolines
Languages : en
Pages : 0
Book Description
Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids
Author: Majid M. Heravi
Publisher: Elsevier
ISBN: 0128240210
Category : Science
Languages : en
Pages : 402
Book Description
Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids includes comprehensive coverage of name reactions in the synthesis of alkaloids. This book highlights the synthesis of various alkaloids using special name reactions including the Diels-Alder, Friedel-Crafts, Heck, Mannich, Pauson-Khand, Pictet-Spengler, Sonogashira and Suzuki reactions. In this book, some selected name reactions in the total synthesis of alkaloids are covered, as they can be used as the key step/steps in the synthesis of different alkaloids exhibiting various biological activities. All chapters include an introduction, history and mechanism of the name reaction, and present the origin of the natural product and its known biological activities. The pathway to total synthesis is visually illustrated, and the focus is on the step in which a name reaction is applied. Chemists working in the area of synthetic organic chemistry will find this reference useful, as well as those working to develop novel methodologies for the synthesis of natural products in both academia and industry. This book is also beneficial to biologists, pharmacists and botanists. Includes an introduction of alkaloids, their origins and biological properties Features the applications of special name reactions as the key step in the total synthesis of featured alkaloids Covers the pathway for the synthesis of alkaloids from commercially available or easily accessible starting materials by using at least one name reaction to achieve the desired target products
Publisher: Elsevier
ISBN: 0128240210
Category : Science
Languages : en
Pages : 402
Book Description
Recent Applications of Selected Name Reactions in the Total Synthesis of Alkaloids includes comprehensive coverage of name reactions in the synthesis of alkaloids. This book highlights the synthesis of various alkaloids using special name reactions including the Diels-Alder, Friedel-Crafts, Heck, Mannich, Pauson-Khand, Pictet-Spengler, Sonogashira and Suzuki reactions. In this book, some selected name reactions in the total synthesis of alkaloids are covered, as they can be used as the key step/steps in the synthesis of different alkaloids exhibiting various biological activities. All chapters include an introduction, history and mechanism of the name reaction, and present the origin of the natural product and its known biological activities. The pathway to total synthesis is visually illustrated, and the focus is on the step in which a name reaction is applied. Chemists working in the area of synthetic organic chemistry will find this reference useful, as well as those working to develop novel methodologies for the synthesis of natural products in both academia and industry. This book is also beneficial to biologists, pharmacists and botanists. Includes an introduction of alkaloids, their origins and biological properties Features the applications of special name reactions as the key step in the total synthesis of featured alkaloids Covers the pathway for the synthesis of alkaloids from commercially available or easily accessible starting materials by using at least one name reaction to achieve the desired target products