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Author: Rizk, Samia Hassan
Publisher: IGI Global
ISBN: 1668458195
Category : Medical
Languages : en
Pages : 591
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Book Description
As hematologic diseases become increasingly complex, accurate diagnosis of bone marrow disorders presents a formidable challenge. Integrating multiple techniques such as cytology, histopathology, and molecular studies demands a high level of competency. Yet, existing training often needs a comprehensive understanding of this intricate diagnostic process. Without proper guidance, bone marrow preparation and examination errors can lead to misdiagnoses and compromised patient care. Principles and Approaches to Diagnostic Bone Marrow Examination offers a structured solution for hematology trainees seeking to master bone marrow diagnosis. Divided into two sections, it covers fundamental knowledge and advanced diagnostic approaches. From the basics of sample preparation to the nuances of integrated diagnostic pathways, each aspect is meticulously detailed to ensure thorough comprehension and skill development.
Author: Rizk, Samia Hassan
Publisher: IGI Global
ISBN: 1668458195
Category : Medical
Languages : en
Pages : 591
Get Book Here
Book Description
As hematologic diseases become increasingly complex, accurate diagnosis of bone marrow disorders presents a formidable challenge. Integrating multiple techniques such as cytology, histopathology, and molecular studies demands a high level of competency. Yet, existing training often needs a comprehensive understanding of this intricate diagnostic process. Without proper guidance, bone marrow preparation and examination errors can lead to misdiagnoses and compromised patient care. Principles and Approaches to Diagnostic Bone Marrow Examination offers a structured solution for hematology trainees seeking to master bone marrow diagnosis. Divided into two sections, it covers fundamental knowledge and advanced diagnostic approaches. From the basics of sample preparation to the nuances of integrated diagnostic pathways, each aspect is meticulously detailed to ensure thorough comprehension and skill development.
Author: Christine Beham-Schmid
Publisher: Springer Nature
ISBN: 3662603098
Category : Medical
Languages : en
Pages : 533
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Book Description
This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.
Author: Kevin Gatter
Publisher: Wiley-Blackwell
ISBN: 9780632042340
Category : Medical
Languages : en
Pages : 160
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Book Description
The diagnosis of bone-marrow disorders by examining sections taken by aspiration or trephine biopsies is essentially a qualitative process requiring the pathologist to identify the abnormal structure and cellularity of bone marrow cells. Until now, the quality of published images in bone-marrow histopathology had been extremely variable--often with the crucial 'message' obscured by poor photography, poor reproduction, or both. The digitally photographed and remastered images in An Illustrated Guide to Bone Marrow Diagnosis are of the highest quality. These images have been copied directly from the microscope in digital format and reproduced in print form. Ideal for the trainee, the text offers comparisons of the common methods of sample collection, fixation and staining, together with a clear description of how to examine a trephine section. Disorders of bone marrow, clinical features, histopathology of bone marrow, and diagnostic problems of each condition are discussed. Chapters end with a summary of key points. The consistent approach in describing each condition makes this text a valuable and handy reference tool for the trained histopathologist.
Author: Barbara J. Bain
Publisher: John Wiley & Sons
ISBN: 1119398126
Category : Medical
Languages : en
Pages : 736
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Book Description
Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as a practical resource with "problems and pitfalls" highlighted throughout to aid laboratory diagnosis.
Author: Daniel A. Cherry
Publisher: CRC Press
ISBN: 9781570597084
Category : Medical
Languages : en
Pages : 210
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Book Description
The intentions of this manual are to familiarize beginners with the process of bone marrow evaluation, to provide a succinct preparatory review of bone marrow pathology for the pathology and clinical hematology board examinations, to remediate practitioners whose knowledge of this field is not current, and to strengthen the skills of clinicians who apply bone marrow data to the care of their patients but who do not independently examine bone marrow specimens. The opening chapter, Bone Marrow Basics, is a review of information that most readers will have originally encountered in medical school. Taking nothing for granted, this material is included for the purpose of closing any possible gaps in the reader’s knowledge of elementary concepts, whether from primary omission or forgetfulness. The next chapter is an overview of the principles and utilities of special studies used for the genotyping and immunophenotyping of BM. It is vital that the reader have a general understanding of these tests, since genetics and antigen expression have now equaled or surpassed the importance of morphology for bone marrow evaluation. The vast majority of this manual is devoted to hematologic neoplasms in the bone marrow and closely follows the World Health Organization classification scheme that has become the international gold standard for the characterization of these disorders. This status has been achieved by integrating all relevant data into their disease definitions, including morphology, immunophenotype, genetics and clinical features. The final two chapters of this manual address specific approaches to evaluating bone marrow that is primarily or secondarily involved by lymphoma and cytopenias due to non-neoplastic causes. It is hoped that the impact of this manual will be some measure of demystification of the unfamiliar morphology, hi-tech ancillary studies and complex disease classification schemes that have made bone marrow pathology so intimidating to so many. Use this book as a starting-off point, and then go move some glass.
Author: Kevin Gatter
Publisher:
ISBN:
Category :
Languages : en
Pages : 68
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Book Description
Author: James A. Strauchen
Publisher:
ISBN: 9780195097566
Category : Medical
Languages : en
Pages : 376
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Book Description
A succinct, single-authored text and atlas of bone marrow pathology, this book is based on over 10,000 bone marrow biopsies. Divided into seven sections, it covers indications and techniques for biopsy, normal findings, and bone marrow alterations in specific neoplastic and non-neoplastic disorders and other diseases. The author approaches the practical problems and pitfalls in making particular types of diagnoses. The volume is lavishly illustrated with over 300 full-color photographs. The emphasis has been placed on the histologic interpretation of the bone marrow core biopsy, but the histopathologic findings have been integrated with clinical and laboratory features, as well as with peripheral blood and bone marrow aspiration morphology. Morphology is, in fact, accorded special attention in this book, since it remains the "gold standard" for many hematologic diagnoses and is the appropriate point of departure for more complex diagnostic investigations. More advanced immunologic and molecular techniques are not overlooked, however, and a discussion of these newer techniques is incorporated in the analysis throughout the text. Written as an introduction and guide to the interpretation of the bone marrow biopsy, this volume is intended primarily for pathologists and pathologists-in-training, but may also be used successfully by hematologists and oncologist who perform bone marrow biopsies.
Author: Nader Rifai
Publisher: Elsevier
ISBN: 0128160624
Category : Science
Languages : en
Pages : 424
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Book Description
Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. - Explains the principles and tools of molecular biology - Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results - Provides a detailed description of current molecular applications used to solve diagnostics tasks
Author: Sa A. Wang
Publisher: Springer
ISBN: 3319202790
Category : Medical
Languages : id
Pages : 413
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Book Description
This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.
Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1461485207
Category : Medical
Languages : en
Pages : 311
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Book Description
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
