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Author: Takashi Kudo
Publisher: Springer
ISBN: 3319262068
Category : Medical
Languages : en
Pages : 144
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Book Description
In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for dementia are used. The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer’s disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. The failure of clinical trials of these drugs to yield satisfactory results has, however, meant that for the time being patients continue to be treated only with symptomatic drugs. There is accordingly a need to become more proficient in the use of symptomatic medicines, and it is against the background of this quest that Practical Pharmacology for Alzheimer’s Disease will be of wide interest.
Author: Takashi Kudo
Publisher: Springer
ISBN: 3319262068
Category : Medical
Languages : en
Pages : 144
Get Book Here
Book Description
In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for dementia are used. The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer’s disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. The failure of clinical trials of these drugs to yield satisfactory results has, however, meant that for the time being patients continue to be treated only with symptomatic drugs. There is accordingly a need to become more proficient in the use of symptomatic medicines, and it is against the background of this quest that Practical Pharmacology for Alzheimer’s Disease will be of wide interest.
Author: Takashi Kudo
Publisher:
ISBN: 9783319262055
Category : Alzheimer's disease
Languages : en
Pages :
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Book Description
The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer's disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. However, the fact that clinical trials of these drugs have not yet yielded satisfactory results has meant that for the time being patients continue to be treated only with symptomatic drugs. Currently, four such drugs are available: donepezil, galantamine, rivastigmine, and memantine. In this book, the four leading experts on each of these drugs explain their practical pharmacology with the aim of providing a sound basis for their use, which to date has been of questionable proficiency. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer's disease and the book closes with an overview of the ways in which symptomatic drugs are used for dementia.
Author: Menghis Bairu
Publisher: Academic Press
ISBN: 0124115306
Category : Medical
Languages : en
Pages : 428
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Book Description
Global Clinical Trials for Alzheimer's Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer's disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer's disease. - Written by leading experts with hands-on experience in designing and running global Alzheimer's disease and other neurodegenerative diseases clinical trials - A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area - Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer's disease global clinical trials in emerging markets and developing countries
Author: Lynette Carl
Publisher: Human Kinetics
ISBN: 0736096043
Category : Medical
Languages : en
Pages : 642
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Book Description
Practical Pharmacology in Rehabilitation discusses the effects of medications in the rehabilitation process and assists rehabilitation professionals in designing patient-specific therapy plans based on coexisting disease states and medications used.
Author: Andrew E. Budson
Publisher: Elsevier Health Sciences
ISBN: 0323316107
Category : Medical
Languages : en
Pages : 293
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Book Description
Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses. Drs. Budson and Solomon — both key leaders in the field — cover the essentials of physical and cognitive examinations and laboratory and imaging studies, giving you the tools you need to consistently make accurate diagnoses in this rapidly growing area. Access in-depth coverage of clinically useful diagnostic tests and the latest treatment approaches. Detailed case studies facilitate the management of both common and uncommon conditions. Comprehensive coverage of hot topics such as chronic traumatic encephalopathy, in addition to new criteria on vascular dementia and vascular cognitive impairment. Includes new National Institute on Aging–Alzheimer's Association and DSM-5 criteria for Alzheimer’s Disease and Mild Cognitive Impairment. Learn how to use new diagnostic tests, such as the amyloid imaging scans florbetapir (Amyvid), flutemetamol (Vizamyl), and florbetaben (Neuraceq), which can display amyloid plaques in the living brains of patients. Updated case studies, many complete with videos illustrating common tests, clinical signs, and diagnostic features, are now incorporated into the main text as clinical vignettes for all major disorders. Brand-new chapters on how to approach the differential diagnosis and on primary progressive aphasia. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Author: Stephen Curran
Publisher: Radcliffe Publishing
ISBN: 9781857759310
Category : Medical
Languages : en
Pages : 252
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Book Description
Practical Management of Dementia: a multi-professional approach brings together a wealth of extensive practical experience and knowledge from a number of multi-professional contributors on how to effectively manage dementia. It is a ready reference for daily use integrating findings from recent research, identifying the challenges faced in caring for the demented. It covers the diagnosis, detection and spiritual needs of caring for patients with dementia, and will help all those interested in the condition have a better understanding of the issues and practicalities which can be done to help pa.
Author: Peter V. Rabins
Publisher: Oxford University Press
ISBN: 0199837902
Category : Medical
Languages : en
Pages : 353
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Book Description
This is a comprehensive yet practical guide to the care and management of patients with dementia from the time of diagnosis to the end of life. It is intended for the increasing number of physicians, nurses, psychologists, social workers, rehabilitation therapists, and long-term care givers responsible for the care of individuals with dementia. For the Second Edition, the authors have added a chapter on mild cognitive impairment. The sections that received the most extensive revision or expansion include those on drug therapy; the pathophysiology of several causes of dementia; psychiatric symptoms of dementia and their treatment (especially drug treatment); and dementia in special environments (especially assisted living and nursing homes).
Author: JoAnn Pfeiffer
Publisher: CRC Press
ISBN: 1315299771
Category : Mathematics
Languages : en
Pages : 292
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Book Description
A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site set-up, subject recruitment, study visits, and to study close-out. Topics include staff roles/responsibilities/training, budget and contract review and management, subject study visits, data and document management, event reporting, research ethics, audits and inspections, consent processes, IRB, FDA regulations, and good clinical practices. Each chapter concludes with a review of key points and knowledge application. Unique to this book is "A View from India," a chapter-by-chapter comparison of clinical trial practices in India versus the U.S. Throughout the book and in Chapter 10, readers will glimpse some of the challenges and opportunities in the emerging and growing market of Indian clinical trials.
Author: Jean M. Stehman
Publisher: JHU Press
ISBN: 9780801852770
Category : Health & Fitness
Languages : en
Pages : 246
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Book Description
Even in the earliest stages of progressive dementia, patients have difficulty evaluating their own needs and engaging in appropriate activities. A therapeutic program of care, including constructive activities and behavior management, is necessary for maximizing patients' functioning and quality of life. The Handbook of Dementia Care and its companion Training Manual and Video for Dementia Care Specialists offer a complete training system for teachers and students providing dementia care in a variety of settings. Developed at the well-known George G. Glenner Alzheimer's Family Centers, the program's instructor's manual and student handbook are organized into six teaching modules: basic information on dementia, positive interaction techniques, supportive physical environment, therapeutic activities, group activities, and family support. Each module is accompanied by a videotaped lecture and demonstration presentation to further illustrate the topic being discussed. This exciting project is a comprehensive instructional tool for dementia care professionals working in adult day centers, long-term care and residential settings, hospitals, nursing homes, and home health care agencies.
Author: Nicola Neale
Publisher: Routledge
ISBN: 1000528146
Category : Medical
Languages : en
Pages : 871
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Book Description
Developing Practical Nursing Skills helps you learn and perfect the practical skills required to become a qualified nurse. Adopting a patient-focused and caring approach, this essential text helps you integrate nursing values alongside physical skills in your daily practice. Now in its fifth edition, the text takes into account the NMC standards of proficiency and is relevant to nurses across all fields. Key features of the book include: i) New chapters on mental health assessment and end-of-life care, along with expanded content on sleep, pain and medication management. ii) Full-colour text design with clear illustrations and clinical photographs to aid visual learning. iii) Reader-friendly style with learning outcomes, activities and reflection points to help you link theory to practice. iv) Scenarios from a range of settings, including community, mental health and learning disabilities nursing. v) A focus on adults and young people, and with 'pointers' on caring for children and pregnant women to promote a lifespan approach. This is a complete clinical skills resource for all pre-registration nursing students. It is also a useful text for nursing associate and healthcare support workers.
