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Author: Jerry Avorn, M.D.
Publisher: Vintage
ISBN: 0307489752
Category : Medical
Languages : en
Pages : 476
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Book Description
If you believe that the latest blockbuster medication is worth a premium price over your generic brand, or that doctors have access to all the information they need about a drug’s safety and effectiveness each time they write a prescription, Dr. Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced. This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans. In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls? Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science.
Author: Jerry Avorn, M.D.
Publisher: Vintage
ISBN: 0307489752
Category : Medical
Languages : en
Pages : 476
Get Book Here
Book Description
If you believe that the latest blockbuster medication is worth a premium price over your generic brand, or that doctors have access to all the information they need about a drug’s safety and effectiveness each time they write a prescription, Dr. Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced. This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans. In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls? Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science.
Author: Arthur Hailey
Publisher: Open Road Media
ISBN: 1504022203
Category : Fiction
Languages : en
Pages : 452
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Book Description
Master storyteller Arthur Hailey’s New York Times–bestselling novel takes readers behind the scenes of the billion-dollar pharmaceutical drug industry It starts as a routine case: Mary Rowe contracts hepatitis from unclean drinking water, and the infection should work its way out of her system in a few days. But when the illness worsens and she slips into a coma, Dr. Andrew Jordan is forced to tell Rowe’s husband that his wife is dying. It’s 1957 and there simply isn’t a drug that can save her. Pharmaceutical saleswoman Celia de Grey then offers Dr. Jordan a sample of an experimental drug that cures the dying woman overnight. This marks the beginning of an epic journey—and a great romance—for a dedicated internist and an idealistic, ambitious woman. The miracle cure establishes de Grey as a rising star within the industry. But as the years pass, she and her husband, Dr. Jordan, begin to realize that her bosses are driven not by the desire to eradicate disease, but by greed. Millions can be made in matters of life and death—for those who don’t mind getting blood on their hands.
Author: Yan Liu
Publisher: University of Washington Press
ISBN: 0295749016
Category : History
Languages : en
Pages : 278
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Book Description
Open access edition: DOI 10.6069/9780295749013 At first glance, medicine and poison might seem to be opposites. But in China’s formative era of pharmacy (200–800 CE), poisons were strategically employed as healing agents to cure everything from abdominal pain to epidemic disease. Healing with Poisons explores the ways physicians, religious figures, court officials, and laypersons used toxic substances to both relieve acute illnesses and enhance life. It illustrates how the Chinese concept of du—a word carrying a core meaning of “potency”—led practitioners to devise a variety of methods to transform dangerous poisons into effective medicines. Recounting scandals and controversies involving poisons from the Era of Division to the Tang, historian Yan Liu considers how the concept of du was central to how the people of medieval China perceived both their bodies and the body politic. He also examines the wide range of toxic minerals, plants, and animal products used in classical Chinese pharmacy, including everything from the herb aconite to the popular recreational drug Five-Stone Powder. By recovering alternative modes of understanding wellness and the body’s interaction with foreign substances, this study cautions against arbitrary classifications and exemplifies the importance of paying attention to the technical, political, and cultural conditions in which substances become truly meaningful. Healing with Poisons is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem) and the generous support of the University of Buffalo.
Author: Fran Quigley
Publisher: Cornell University Press
ISBN: 1501713922
Category : Social Science
Languages : en
Pages : 244
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Book Description
In Prescription for the People, Fran Quigley diagnoses our inability to get medicines to the people who need them and then prescribes the cure. He delivers a clear and convincing argument for a complete shift in the global and U.S. approach to developing and providing essential medicines—and a primer on how to make that change happen. Globally, 10 million people die each year because they are unable to pay for medicines that would save them. The cost of prescription drugs is bankrupting families and putting a strain on state and federal budgets. Patients’ desperate need for affordable medicines clashes with the core business model of the powerful pharmaceutical industry, which maximizes profits whenever possible. It doesn’t have to be this way. Patients and activists are aiming to make all essential medicines affordable by reclaiming medicines as a public good and a human right, instead of a profit-making commodity. In this book, Quigley demystifies statistics and terminology, offers solutions to the problems that block universal access to medicines, and provides a road map for activists wanting to make those solutions a reality.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486483
Category : Medical
Languages : en
Pages : 175
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Book Description
The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.
Author: James L. Marcum
Publisher: Tyndale House Publishers, Inc.
ISBN: 1414382804
Category : Religion
Languages : en
Pages : 258
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Book Description
The recent deaths of celebrities like Michael Jackson, Anna Nicole Smith, Heath Ledger, and Whitney Houston have shown a spotlight on the overuse and abuse of prescription drugs. Most people believe that prescription drugs are safer than illegal substances. But, when combined with other over-the-counter sedatives, prescription drugs can be every bit as powerful, addictive, and dangerous. In 2006, overdoses on a class of prescription pain relievers called opioid analgesics killed more people than those killed by overdoses on cocaine and heroin combined. Right now, among 35 to 54 year olds, poisoning by prescription drugs is the most common cause of accidental death—even more so than auto-related deaths. In Medicines That Kill, Dr. Marcum shines a light on the addictive power of prescription medication and how you can protect yourself and your family by practicing healthy habits.
Author: Ben Goldacre
Publisher: Macmillan
ISBN: 0865478066
Category : Business & Economics
Languages : en
Pages : 479
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Book Description
Originally published in 2012, revised edition published in 2013, by Fourth Estate, Great Britain; Published in the United States in 2012, revised edition also, by Faber and Faber, Inc.
Author: E. Richard Brown
Publisher: Univ of California Press
ISBN: 9780520042698
Category : History
Languages : en
Pages : 308
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309468086
Category : Medical
Languages : en
Pages : 235
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Book Description
Thanks to remarkable advances in modern health care attributable to science, engineering, and medicine, it is now possible to cure or manage illnesses that were long deemed untreatable. At the same time, however, the United States is facing the vexing challenge of a seemingly uncontrolled rise in the cost of health care. Total medical expenditures are rapidly approaching 20 percent of the gross domestic product and are crowding out other priorities of national importance. The use of increasingly expensive prescription drugs is a significant part of this problem, making the cost of biopharmaceuticals a serious national concern with broad political implications. Especially with the highly visible and very large price increases for prescription drugs that have occurred in recent years, finding a way to make prescription medicinesâ€"and health care at largeâ€"more affordable for everyone has become a socioeconomic imperative. Affordability is a complex function of factors, including not just the prices of the drugs themselves, but also the details of an individual's insurance coverage and the number of medical conditions that an individual or family confronts. Therefore, any solution to the affordability issue will require considering all of these factors together. The current high and increasing costs of prescription drugsâ€"coupled with the broader trends in overall health care costsâ€"is unsustainable to society as a whole. Making Medicines Affordable examines patient access to affordable and effective therapies, with emphasis on drug pricing, inflation in the cost of drugs, and insurance design. This report explores structural and policy factors influencing drug pricing, drug access programs, the emerging role of comparative effectiveness assessments in payment policies, changing finances of medical practice with regard to drug costs and reimbursement, and measures to prevent drug shortages and foster continued innovation in drug development. It makes recommendations for policy actions that could address drug price trends, improve patient access to affordable and effective treatments, and encourage innovations that address significant needs in health care.
Author: Peter C. Mancall
Publisher: Cornell University Press
ISBN: 150172844X
Category : History
Languages : en
Pages : 290
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Book Description
"An important work of scholarship, with powerful, concise, and objective insights into the complicated history of alcohol use among Native American peoples. Impeccably researched, cogently argued and clearly written, Peter Mancall's book is both an eye-opener for the lay reader and an invaluable resource for the expert."— Michael Dorris, author of The Broken Cord: A Family's Ongoing Struggle with Fetal Alcohol Syndrome Alcohol abuse has killed and impoverished American Indians since the seventeenth century, when European settlers began trading rum for furs. In the first book to probe the origins of this ongoing social crisis, Peter C. Mancall explores the liquor trade's devastating impact on the Indian communities of colonial America. Mancall recounts how English settlers quickly found a market for alcohol among the Indians, and traffic in rum became a prominent source of revenue for the British Empire. In spite of the colonists' growing awareness that some Indians abused alcohol and that drinking threatened the stability of countless Indian villages already decimated by European diseases, they expanded the liquor trade into virtually every Indian community from the Atlantic to the Mississippi. In response, Indians created one of the most important temperance movements in American history, a movement that was nevertheless unable to halt the lucrative commerce. The author follows the trail of rum from the West Indian producers to the colonial distributors and on to the Indian consumers in the eastern woodlands. To discover why Indians participated in the trade and why they experienced such a powerful desire for alcohol, he addresses current medical views on alcoholism and reexamines the colonial era as a time when Indians were forming new strategies for survival in a world that had been radically changed. Finally, Mancall compares Indian drinking in New France and New Spain with that in the British colonies. Forever shattering the stereotype of the drunken Indian, Mancall offers a powerful indictment of English participation in the liquor trade and a new awareness or the trade's tragic cost for the American Indians.
