Human Variation

Human Variation PDF Author: Aravinda Chakravarti
Publisher:
ISBN: 9781936113255
Category : Science
Languages : en
Pages : 200

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Book Description
"A subject collection from Cold Spring Harbor perspectives in medicine."

Human Variation

Human Variation PDF Author: Aravinda Chakravarti
Publisher:
ISBN: 9781936113255
Category : Science
Languages : en
Pages : 200

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Book Description
"A subject collection from Cold Spring Harbor perspectives in medicine."

Evaluating Human Genetic Diversity

Evaluating Human Genetic Diversity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309184746
Category : Science
Languages : en
Pages : 101

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Book Description
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

Human Population Genetics and Genomics

Human Population Genetics and Genomics PDF Author: Alan R. Templeton
Publisher: Academic Press
ISBN: 0123860261
Category : Science
Languages : en
Pages : 500

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Book Description
Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. - Comprehensively explains the use of population genetics and genomics in medical applications and research - Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals - Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

Human Biological Variation

Human Biological Variation PDF Author: James H. Mielke
Publisher: Oxford University Press, USA
ISBN: 9780195387407
Category : Nature
Languages : en
Pages : 443

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Book Description
This text explores human biological variation in its broadest sense - from the molecular to the physiological and morphological - focusing on the micro-evolutionary analysis of genetic variation among recent human populations. Authoritative yet accessible, Human Biological Variation, SecondEdition, opens with an engaging introduction to basic genetics and the evolutionary forces that set the stage for understanding human diversity. It goes on to offer a clear and detailed discussion of molecular genetics, including its uses and its relationship to anthropological and evolutionarymodels. The text features up-to-date discussions of classic genetic markers (blood groups, enzymes, and proteins) along with extensive background on DNA analysis and coverage of satellite DNA, single nucleotide polymorphisms (SNPs), and Alu inserts. Coverage includes current issues such as themeaning and significance of "race," quantitative genetics and the "nature versus nurture" debates, biocultural interactions, population structure, and cultural and historical influences on patterns of human variation. Integrating real-world examples on interesting topics - including dyslexia, IQ,and homosexuality - this second edition of Human Biological Variation provides the most thorough and contemporary view of our biological diversity.

Human Population Genetics

Human Population Genetics PDF Author: John H. Relethford
Publisher: John Wiley & Sons
ISBN: 0470464674
Category : Science
Languages : en
Pages : 326

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Book Description
Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf

Frontiers in the Nutrition Sciences

Frontiers in the Nutrition Sciences PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309041465
Category : Medical
Languages : en
Pages : 241

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Book Description
This series of individually authored chapters examines the nature and extent of scientific advances in the nutrition sciences and describes both future opportunities in the field and barriers to progress. Despite concern about declining attention to nutrition in universities and medical schools, the authors offer a bright and challenging future in nutrition research and training that should generate enthusiasm among young researchers and teachers for this indispensable component of biology.

Statistical Population Genomics

Statistical Population Genomics PDF Author: Julien Y Dutheil
Publisher:
ISBN: 9781013271403
Category : Science
Languages : en
Pages : 464

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Book Description
This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Population Structure and Human Variation

Population Structure and Human Variation PDF Author: G. A. Harrison
Publisher: Cambridge University Press
ISBN: 9780521213998
Category : Science
Languages : en
Pages : 368

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Book Description
This volume is a collection of eleven studies conducted during the International Biological Programme on the biological structure of human populations.

On Human Nature

On Human Nature PDF Author: Michel Tibayrenc
Publisher: Academic Press
ISBN: 0127999159
Category : Science
Languages : en
Pages : 816

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Book Description
On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters. This transdisciplinary work brings together specialists from various fields who rarely interact, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Genomic diversity is covered in several chapters dealing with biology, including the differences in men and apes and the genetic diversity of mankind. Top specialists, known for their open mind and broad knowledge have been carefully selected to cover each topic. The book is therefore at the crossroads between biology and human sciences, going beyond classical science in the Popperian sense. The book is accessible not only to specialists, but also to students, professors, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon. - Provides greater understanding of diversity and population structure and history, with crucial foundational knowledge needed to conduct research in a variety of fields, such as genetics and disease - Includes three robust sections on biological, psychological, and ethical aspects, with cross-fertilization and reciprocal references between the three sections - Contains contributions by leading experts in their respective fields working under the guidance of internationally recognized and highly respected editors

A Companion to Anthropological Genetics

A Companion to Anthropological Genetics PDF Author: Dennis H. O'Rourke
Publisher: John Wiley & Sons
ISBN: 111876899X
Category : Social Science
Languages : en
Pages : 496

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Book Description
Explore the latest research in anthropological genetics and understand the genome’s role in cultural and social development A Companion to Anthropological Genetics illustrates the role of genetic analysis in advancing the modern study of human origins, populations, evolution, and diversity. Broad in scope, this essential reference work establishes and explores the relationship between genetic research and the major questions of anthropological study. Through contributions by leading researchers, this collection explores molecular genetics and evolutionary mechanisms in the context of macro- and microevolution, paleontology, phylogeny, diet, and disease, with detailed explanations of quantitative methods, including coalescent and approximate Bayesian computation. With an emphasis on contextualizing new and developing genetic research within anthropological frameworks, this text offers critical perspective on the conditions of molecular evolution that accompany cultural and social transformation, while also addressing critical disciplinary questions, such as the ethical issues surrounding ancestry testing and community-based genetic research. Acts as an essential reference on the contributions of genetic science to the field of anthropology Features new work by leading researchers of the field Explores the evolution of immunity, including the genetics and epigenetics of pathogens, chronic illness, and disease resistance Provides in-depth examination of mutation and dietary adaptation, including AMY1, lactase persistence, and sensory polymorphisms Explains essential quantitative and phylogenetic methods for aligning genomic analysis with evolution and migration time scales Offering thorough coverage on leading questions and developing research, A Companion to Anthropological Genetics is a comprehensive resource for students and scholars.