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Author: J. Milton Harris
Publisher: Springer Science & Business Media
ISBN: 1489907033
Category : Medical
Languages : en
Pages : 395
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Book Description
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre sented in the book, and the book incorporates much work done after the meeting. The book does not include contributions in all related areas to which PEG chemistry has been applied. Several invited researchers declined to parti.:ipate, and there is not enough space in this single volume to properly cover all submissions. Chapter I-an overview of the topic-discusses in brief applications not given detailed coverage in specifically devoted chapters. The following topics are covered: introduction to and fundamental properties of PEG and derivatives in Chapters 1-3; separations using aqueous polymer two-phase partitioning in Chapters 4-6; PEG-proteins as catalysts in biotechnical applications in Chapters 7 and 8; biomedical applications of PEG-proteins in Chapters 9-13; PEG modified surfaces for a variety of biomedical and biotechnical applications in Chapters 14-20; and synthesis of new PEG derivatives in Chapters 21 and 22.
Author: J. Milton Harris
Publisher: Springer Science & Business Media
ISBN: 1489907033
Category : Medical
Languages : en
Pages : 395
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Book Description
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre sented in the book, and the book incorporates much work done after the meeting. The book does not include contributions in all related areas to which PEG chemistry has been applied. Several invited researchers declined to parti.:ipate, and there is not enough space in this single volume to properly cover all submissions. Chapter I-an overview of the topic-discusses in brief applications not given detailed coverage in specifically devoted chapters. The following topics are covered: introduction to and fundamental properties of PEG and derivatives in Chapters 1-3; separations using aqueous polymer two-phase partitioning in Chapters 4-6; PEG-proteins as catalysts in biotechnical applications in Chapters 7 and 8; biomedical applications of PEG-proteins in Chapters 9-13; PEG modified surfaces for a variety of biomedical and biotechnical applications in Chapters 14-20; and synthesis of new PEG derivatives in Chapters 21 and 22.
Author: J. Milton Harris
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 512
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Book Description
This volume provides an interdisciplinary analysis of current biological applications of poly(ethylene glycol) (PEG). It includes a wide array of topics useful to materials scientists, organic chemists, biochemists, and bioengineers interested in drug delivery systems, pharmaceuticals and other biomaterials. The applications discussed include PEG-modified proteins, liposomes, drugs, surfaces of materials, and hydrogels. The volume also includes a review of PEG-oligonucleotides and a concise summary of the toxicology of PEG and its derivatives.
Author: Francesco M. Veronese
Publisher: Springer Science & Business Media
ISBN: 3764386797
Category : Medical
Languages : en
Pages : 289
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Book Description
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Author: Zhen-Zhen Yang
Publisher: Springer Science & Business Media
ISBN: 3642312683
Category : Science
Languages : en
Pages : 88
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Book Description
In this volume, Professor He and his coworkers summarize polyethylene glycol (PEG)-promoted CO2 chemistry on the basis of understanding about phase behavior of PEG/CO2 system and reaction mechanism at molecular level. As PEG could be utilized as a green replacement for organic solvents, phase-transfer catalyst, surfactant, support in various reaction systems, significantly promoting catalytic activity and recovering expensive metal catalysts, particularly regarded as a CO2-philic material, the authors focus on special applications of PEG in CO2 capture and utilization, including PEG-functionalized catalysts for efficient transformation of CO2 and PEG-functionalized absorbents for efficient CO2 capture. Furthermore, they describe carbon capture and utilization strategy as an alternative approach to address the energy penalty problem in carbon capture and storage. Interestingly, the authors also discuss PEG radical chemistry in dense CO2 as rather creative and unusual use of PEG, presumably serves as a reaction medium and a radical initiator for radical chemistry.
Author: G. W. A. Milne
Publisher: John Wiley & Sons
ISBN: 0471736619
Category : Technology & Engineering
Languages : en
Pages : 1205
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Book Description
An exhaustive resource for the industrial chemical community Through eleven editions, Gardner's Chemical Synonyms and Trade Names has become the best-known and most widely used source of information on chemicals in commerce. This companion book reflects the continuing research underlying Gardner's and presents a major expansion of the information provided for individual chemical compounds. Gardner's Commercially Important Chemicals: Synonyms, Trade Names, and Properties: * Contains 4,174 chemical entries and information such as structure, molecular formula, and chemical name * Includes synonyms for each chemical, including other identifiers, chemical names, trade names, and trivial names, in English and other languages * Provides chemical properties of the compounds, information concerning known uses of the chemical and biological data-in particular, acute toxicity in various species, where available * Lists the companies that manufacture or supply the listed chemicals * Describes bulk inorganic chemicals, major pesticides (herbicides, insecticides, antifungal agents, etc.), and many dyestuffs, surfactants, and metals, along with the most commonly used drugs * Contains indexes by chemical name and synonym, Chemical Abstracts Service (CAS) Registry Numbers, and EINECS (European Inventory of Existing Commercial Substances) numbers One useful feature of this database is the inclusion of physical properties and use data for pure chemicals. Properties that have been provided, when available, include: the melting point, boiling point, density or specific gravity, optical rotation, ultraviolet absorption, solubility, and acute toxicity. The major uses of most of the chemicals are indicated and, where appropriate, regulatory information is also provided.
Author: United States. Environmental Protection Agency. Office of Toxic Substances
Publisher:
ISBN:
Category : Chemical industry
Languages : en
Pages : 806
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Book Description
Author: United States. Environmental Protection Agency. Office of Toxic Substances
Publisher:
ISBN:
Category : Chemical industry
Languages : en
Pages : 808
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 266
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Book Description
Author: Sarfaraz K. Niazi
Publisher: CRC Press
ISBN: 1351592238
Category : Medical
Languages : en
Pages : 453
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Book Description
The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Six, Sterile Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this sixth volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features: Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines
Author:
Publisher:
ISBN:
Category : Coal-tar industry
Languages : en
Pages : 454
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Book Description
