Platelets as Players in Neuropathologies: Novel Diagnostic and Therapeutic Targets PDF Download
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Author: Jacqueline Monique Orian
Publisher: Frontiers Media SA
ISBN: 2889716872
Category : Medical
Languages : en
Pages : 120
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Book Description
Author: Jacqueline Monique Orian
Publisher: Frontiers Media SA
ISBN: 2889716872
Category : Medical
Languages : en
Pages : 120
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Book Description
Author: Paolo Gresele
Publisher: Springer
ISBN: 3319474626
Category : Medical
Languages : en
Pages : 1402
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Book Description
This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
Author: Abel Lajtha
Publisher: Springer Science & Business Media
ISBN: 0306465795
Category : Medical
Languages : en
Pages : 304
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Book Description
This book looks at the role of proteases, which are enzymes that digest proteins, and the various roles that proteases play in the development of neurodegenerative diseases such as Alzheimer's disease, ALS, epilepsy, multiple sclerosis, as well as numerous other neuromuscular diseases.
Author: Rafael Pulido
Publisher:
ISBN: 9783039216895
Category : Biology (General)
Languages : en
Pages : 240
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Book Description
Dual specificity phosphatases (DUSPs) constitute a heterogeneous group of protein tyrosine phosphatases with the ability to dephosphorylate Ser/Thr and Tyr residues from proteins, as well as from other non-proteinaceous substrates including signaling lipids. DUSPs include, among others, MAP kinase (MAPK) phosphatases (MKPs) and small-size atypical DUSPs. MKPs are enzymes specialized in regulating the activity and subcellular location of MAPKs, whereas the function of small-size atypical DUSPs seems to be more diverse. DUSPs have emerged as key players in the regulation of cell growth, differentiation, stress response, and apoptosis. DUSPs regulate essential physiological processes, including immunity, neurobiology and metabolic homeostasis, and have been implicated in tumorigenesis, pathological inflammation and metabolic disorders. Accordingly, alterations in the expression or function of MKPs and small-size atypical DUSPs have consequences essential to human disease, making these enzymes potential biological markers and therapeutic targets. This Special Issue covers recent advances in the molecular mechanisms and biological functions of MKPs and small-size atypical DUSPs, and their relevance in human disease.
Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718
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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Author: Pedro Bekinschtein
Publisher: Frontiers Media SA
ISBN: 2889637875
Category :
Languages : en
Pages : 104
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Book Description
Author: Suresh I.S. Rattan
Publisher: Springer Science & Business Media
ISBN: 1402050585
Category : Medical
Languages : en
Pages : 365
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Book Description
This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.
Author: Pedro L. Gambús
Publisher: Cambridge University Press
ISBN: 1107579252
Category : Medical
Languages : en
Pages : 315
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Book Description
Presents a modern vision of anaesthesia, integrating technology and knowledge, to change how anaesthesia is taught and practised.
Author: G. Gary Demerjian
Publisher: Springer
ISBN: 3319763679
Category : Medical
Languages : en
Pages : 263
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Book Description
This book on the local and systemic manifestations and correlates of temporomandibular joint disorders (TMDs) encompasses the two intertwined facets of translational science – translational research and translational effectiveness – as they relate specifically to TMDs. The first part of the book, on recent translational research, focuses on topics such as the neuroanatomy and neurophysiology of the trigeminal nerve and trigeminal network system, the manifestations of neuroinflammation in TMDs, and the molecular mechanisms underlying TMDs. The second part discusses the clinical effectiveness of treatment approaches from the perspective of evidence-based dentistry, with careful attention to the critical relationships between dental malocclusions, the signs and symptoms of TMDs, and airway/breathing disorders. Interventions to correct for malocclusal conditions that lead to TMDs are examined, with explanation of the ways in which they can ameliorate a variety of local and systemic symptoms. This will be an excellent reference book for established practitioners, residents, interns, and students as well as a powerful cutting-edge document for researchers in the field.
Author: Hans-Christoph Pape
Publisher: Springer Science & Business Media
ISBN: 0387895086
Category : Medical
Languages : en
Pages : 462
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Book Description
This guide to damage control surgery focuses on the decision-making process for managing polytrauma. Orthopedists, trauma surgeons, and emergency medicine physicians will learn how to effectively coordinate efforts. The book presents an overview of the damage control concept and the epidemiology of polytrauma injuries. Immunological changes, cascade reactions, and patient selection are discussed. Indications for life-saving procedures, damage control for truncal injuries, and damage control for extremities and pelvic fractures are outlined as well. The text also covers vascular injuries and secondary definitive procedures.
