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Author: Jorge Hidalgo
Publisher: Springer Nature
ISBN: 3031141385
Category : Medical
Languages : en
Pages : 372
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Book Description
In dealing with the unprecedented COVID-19 pandemic, there are an increased number of patients requiring personalized management as the disease pathology varies. With variable lung compliance and airway resistance as well as the severity of the disease, one size will not fit all patients. This book is problem-oriented with evidence-based discussions of the daily encountered scenarios in the ICU for mechanically ventilated patients, dealing with the pathology, monitoring and troubleshooting facing intensivists daily. These scenarios are managed utilizing a goal-directed approach and algorithms to achieve these goals. All chapters contain an explanation of a different solution illustrating the respiratory mechanics, physiology and pathology involved in such a scenario. Each chapter also closes with a take-home message to summarize the content. In addition to describing the ventilation of different patient categories, this text also features ventilation cases specific to COVID-19 including airway management in the enhanced air born isolated patient, pulmonary embolism, different states of shock and differential lung ventilation. There is also a specific chapter on monitoring mechanical ventilation with point of care ultrasound, which is an available modality in most ICUs. Another unique chapter describes how to connect more than one patient to one ventilator in case of a shortage of machines. Written by experts in the field, Personalized Mechanical Ventilation is a timely and valuable resource for critical care physicians, nurses and respiratory therapists on the front lines of both COVID-19 and day-to-day care of mechanically ventilated patients in the ICU.
Author: Jorge Hidalgo
Publisher: Springer Nature
ISBN: 3031141385
Category : Medical
Languages : en
Pages : 372
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Book Description
In dealing with the unprecedented COVID-19 pandemic, there are an increased number of patients requiring personalized management as the disease pathology varies. With variable lung compliance and airway resistance as well as the severity of the disease, one size will not fit all patients. This book is problem-oriented with evidence-based discussions of the daily encountered scenarios in the ICU for mechanically ventilated patients, dealing with the pathology, monitoring and troubleshooting facing intensivists daily. These scenarios are managed utilizing a goal-directed approach and algorithms to achieve these goals. All chapters contain an explanation of a different solution illustrating the respiratory mechanics, physiology and pathology involved in such a scenario. Each chapter also closes with a take-home message to summarize the content. In addition to describing the ventilation of different patient categories, this text also features ventilation cases specific to COVID-19 including airway management in the enhanced air born isolated patient, pulmonary embolism, different states of shock and differential lung ventilation. There is also a specific chapter on monitoring mechanical ventilation with point of care ultrasound, which is an available modality in most ICUs. Another unique chapter describes how to connect more than one patient to one ventilator in case of a shortage of machines. Written by experts in the field, Personalized Mechanical Ventilation is a timely and valuable resource for critical care physicians, nurses and respiratory therapists on the front lines of both COVID-19 and day-to-day care of mechanically ventilated patients in the ICU.
Author: Erwan Laroche
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Computed tomography (CT) scan lung attenuation has contributed to the recognition of focal and nonfocal phenotypes (or morphotypes), with distinct prognosis and therapeutic responses among patients with acute respiratory distress syndrome (ARDS). Plasma soluble receptor for advanced glycation end-products (sRAGE) is a marker of alveolar type I cell injury, of impaired alveolar fluid clearance, and of a nonfocal morphotype that correlates with the severity and outcome of ARDS. The objectives were to verify whether baseline plasma sRAGE discriminates between focal and nonfocal ARDS and correlates with the severity and clinical outcomes of ARDS. In addition, this stuy investigated whether changes in plasma sRAGE could inform on prognosis in ARDS and wherher plasma sRAGE kinetics over the first days following ARDS onset would be impacted differentially in focal and nonfocal morphotypes by a personalized morphotpe-targeted ventilation strategy compared to the use of a more conventional mow tidal volume strategy. Plasma sRAGE levels were measured from 235 subjects enrolled in a large multicenter randomized controlled trial of lung imaging for ventilator setting in ARDS (LIVE study). Baseline plasma sRAGE was higher in patients with nonfocal ARDS than in those with focal ARDS (median [IQR], 3,577 [2,113-8,480] pg.mL ̄1vs. 2,346 [1,133-3,218] pg.mL ̄1, P = 0.0001), and it was associated with an increased severity of ARDS. Baseline plasma sRAGE was independently associated wiht 90-day mortality in patients ventiladed with a personalized strategy, but not in those ventilated wiht a conventional low tidal volume strategy. Higher day two-to-day zero and day three-to-day zero plasma sRAGE ratios were both associated with higher 90-day mortality (HR 1.08; 95% CI 1.01 to 1.15; P = 0.02 and 1.08; 95% CI 1.02 to 1.14; P = 0.01, respectively), regardless of the study group and ARDS morphotype. There was a significant decrease in plasma sRAGE on days two and three (P = 0.02 for both timepoints) in patients with focal ARDS ventiladed with a personalized strategy. In contrast, there was a significant increase in plasma sRAGE at all timepoints (P= 0.02, 0.004, 0.01, 0.01, and 0.001 for days one, two, three, four, and six, respectively) in patients with focal ARDS ventilated with a strategy combining higher positive end-expiratory pressure and recruitment maneuvers. Plasma sRAGE decreased at all timepoints in nonfocal ARDS when the morphotype was correctly classified at baseline, but it only decreased on days three and four when it was not. Changes in plasma sRAGE at days two and three following ARDS onset were associated whit higher 90-day mortality in patients with ARDS, regardless of the study group and ARDS morphotype. A personalized approach to the ventilation of patients with focal or nonfocal ARDS may be beneficial, in part by decreasing injury to the alveolar epithelium. Plama sRAGE is a promising biomarker for endotyping patients with ARDS and for monitoring responses to ventilator settings in ARDS.
Author: Didier Dreyfuss
Publisher: CRC Press
ISBN: 1420019260
Category : Medical
Languages : en
Pages : 776
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Book Description
This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Cons
Author: M. Ferrer
Publisher: European Respiratory Society
ISBN: 1849840229
Category : Medical
Languages : en
Pages : 248
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Book Description
Mechanical ventilation is the life-support technique most frequently used in critically ill patients admitted to intensive care units. This Monograph discusses conventional and innovative ventilator modalities, adjuvant therapies, modes of extracorporeal respiratory support, and weaning from mechanical ventilation and noninvasive ventilation.
Author: Arthur S. Slutsky
Publisher: Springer Science & Business Media
ISBN: 3540267913
Category : Medical
Languages : en
Pages : 418
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Book Description
Mechanical ventilation is a life-saving procedure that has been used for decades to treat patients with respiratory failure. In recent years there have been major advances in our understanding of how to ventilate patients, when to initiate and discontinue ventilation, and importantly, the side effects of mechanical ventilation. This book represents a state-of-the-art review by the leading experts in this field and covers a number of important topics including epidemiology, underlying physiological concepts, and approaches to monitoring. The pros and cons of various modes of ventilation are reviewed, as are novel forms of ventilation that may play a role in the future management of patients with respiratory failure. The importance of patient-ventilator synchrony and ventilator-induced lung injury are reviewed, with a focus on recent clinical trials and the challenges of implementing the results into clinical practice.
Author: Peter J. Papadakos
Publisher: Elsevier Health Sciences
ISBN: 1437712991
Category : Medical
Languages : en
Pages : 685
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Book Description
One of the key tools in effectively managing critical illness is the use of mechanical ventilator support. This essential text helps you navigate this rapidly evolving technology and understand the latest research and treatment modalities. A deeper understanding of the effects of mechanical ventilation will enable you to optimize patient outcomes while reducing the risk of trauma to the lungs and other organ systems. A physiologically-based approach helps you better understand the impact of mechanical ventilation on cytokine levels, lung physiology, and other organ systems. The latest guidelines and protocols help you minimize trauma to the lungs and reduce patient length of stay. Expert contributors provide the latest knowledge on all aspects of mechanical ventilation, from basic principles and invasive and non-invasive techniques to patient monitoring and controlling costs in the ICU. Comprehensive coverage of advanced biological therapies helps you master cutting-edge techniques involving surfactant therapy, nitric oxide therapy, and cytokine modulators. Detailed discussions of both neonatal and pediatric ventilator support helps you better meet the unique needs of younger patients.
Author: Neil R. MacIntyre
Publisher: Elsevier Health Sciences
ISBN: 0323477577
Category : Medical
Languages : en
Pages :
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Book Description
This issue of Clinics in Chest Medicine focuses on Advances in Mechanical Ventilation. Articles include: Mechanical Ventilation Design Features; Assessing Respiratory System Mechanical Function; Ventilator Induced Lung Injury; Managing Acute Lung Injury; Patient-Ventilator Interactions; Extracorporeal Gas Exchange; Preventing Ventilator Associated Infections; Ventilator Discontinuation Process; Ventilator Management of the Non-injured Lung; Non-invasive Ventilation; and more!
Author: Antonio M. Esquinas
Publisher: Springer Nature
ISBN: 3031289633
Category : Medical
Languages : en
Pages : 826
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Book Description
The 3rd and updated edition of this book represents a new and unique scientific reference for the medical community on how to understand rationale and applications of noninvasive mechanical ventilation (NIMV). Its aim is to establish the indications of NIMV in critically ill patients in weaning from invasive MV. Nowadays, there is a growing evidence-based medicine that recommends use of NIMV in patients after extubation or in difficult weaning patients also affected by comorbidities. This book has been conceived with the vision or providing the best resources for everyone working in ICUs even if belonging to different specialties (intensive care, anesthesiology, pneumology, emergency medicine, etc.). Considering the enormous increase of literature on this topic, authors have selected major key topics related to NIMV, excluding those with low rate of interest, have updated previous topics and have introduced new items collecting them in a practical book analyzing major key topics for a correct practical applications. A new gaze has been devoted to emergency medicine and prehospital applications and technical developments (new ventilation modes: neurology adaptive modes, average support mode and to the development of synchronization and patient-ventilator interaction result). A section dedicated to sleep medicine - due to the new interesting studies on NIV-CPAP adaptation studies, clinical impacts of CPAP devices and ventilatory modes representing an essentials development for a new adequate analysis - is now included. A part devoted to clinical indications based on the observation of new clinical indications in anesthesiology and pneumology in NIV as complementary technique for procedures like bronchoscopy, pre-oxygenation and difficult endotracheal intubations is also now foreseen.
Author: Sandra Goldsworthy
Publisher: Springer Publishing Company
ISBN: 0826198066
Category : Medical
Languages : en
Pages : 177
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Book Description
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Author: Haibo Qiu
Publisher: Frontiers Media SA
ISBN: 2889767981
Category : Medical
Languages : en
Pages : 135
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Book Description
