Peripheral Immunity in Parkinson's Disease: Emerging Role and Novel Target for Therapeutics

Peripheral Immunity in Parkinson's Disease: Emerging Role and Novel Target for Therapeutics PDF Author: Cristoforo Comi
Publisher: Frontiers Media SA
ISBN: 2889632857
Category :
Languages : en
Pages : 150

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Peripheral Immunity in Parkinson's Disease: Emerging Role and Novel Target for Therapeutics

Peripheral Immunity in Parkinson's Disease: Emerging Role and Novel Target for Therapeutics PDF Author: Cristoforo Comi
Publisher: Frontiers Media SA
ISBN: 2889632857
Category :
Languages : en
Pages : 150

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Book Description


Etiology of Parkinson's Disease

Etiology of Parkinson's Disease PDF Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600

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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Prodromal Parkinson’s Disease

Prodromal Parkinson’s Disease PDF Author: David Crosiers
Publisher: Frontiers Media SA
ISBN: 2889664899
Category : Medical
Languages : en
Pages : 90

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Leucine-Rich Repeat Kinase 2 (LRRK2)

Leucine-Rich Repeat Kinase 2 (LRRK2) PDF Author: Hardy J. Rideout
Publisher: Springer
ISBN: 3319499696
Category : Medical
Languages : en
Pages : 271

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Book Description
This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

Peripheral Immune System and Neurodegenerative Disease

Peripheral Immune System and Neurodegenerative Disease PDF Author: Ke Zhang
Publisher: Frontiers Media SA
ISBN: 2889769755
Category : Science
Languages : en
Pages : 141

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Inflammation in Parkinson's Disease

Inflammation in Parkinson's Disease PDF Author: Madhavi Thomas
Publisher: Springer
ISBN: 3319080466
Category : Medical
Languages : en
Pages : 236

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Book Description
Parkinson’s Disease (PD) is a progressive neurodegenerative disease with a prevalence of 0.1% of the global population, and 5-10% patients are under 40 years of age. Several text books have been published on various aspects of PD to date, including research and clinical aspects. However these do not emphasize the inflammatory pathways and pathways of neurodegeneration in PD. Inflammation in Parkinson’s Disease brings advances in research together with current literature and evidence. This concise volume covers the fundamentals of neuroimmunology and inflammatory models, the interactions between pathways of neurodegeneration and follows the concept of research work undertaken from basic science to clinical trials. Researchers, clinicians, and students interested in Parkinson's Disease are provided with a comprehensive view of translational research methods and an insight needed for developing future therapies aimed at disease modulation.

Brain Neurotrauma

Brain Neurotrauma PDF Author: Firas H. Kobeissy
Publisher: CRC Press
ISBN: 1466565993
Category : Medical
Languages : en
Pages : 718

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Book Description
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Multiple Sclerosis

Multiple Sclerosis PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309072859
Category : Medical
Languages : en
Pages : 457

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Book Description
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Pathogenesis of Neurodegenerative Disorders

Pathogenesis of Neurodegenerative Disorders PDF Author: Mark P. Mattson
Publisher:
ISBN: 9781468496444
Category :
Languages : en
Pages : 308

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Crosstalk between Peripheral and Local Immune Response in the Pathophysiology of Stroke and Neurodegeneration Diseases

Crosstalk between Peripheral and Local Immune Response in the Pathophysiology of Stroke and Neurodegeneration Diseases PDF Author: Yuanjian Fang
Publisher: Frontiers Media SA
ISBN: 2832541461
Category : Medical
Languages : en
Pages : 363

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Book Description