Author: Jie Tian
Publisher: Frontiers Media SA
ISBN: 2832533051
Category : Medical
Languages : en
Pages : 138
Book Description
Perioperative Chemotherapy
Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Anesthesia and Perioperative Care of the High-Risk Patient
Author: Ian McConachie
Publisher: Cambridge University Press
ISBN: 1107690579
Category : Medical
Languages : en
Pages : 501
Book Description
A concise summary of perioperative management of high-risk surgical patients, bridging the gap between the operating theatre and ICU.
Publisher: Cambridge University Press
ISBN: 1107690579
Category : Medical
Languages : en
Pages : 501
Book Description
A concise summary of perioperative management of high-risk surgical patients, bridging the gap between the operating theatre and ICU.
Perioperative Management and Cancer Outcome
Author: Jie Tian
Publisher: Frontiers Media SA
ISBN: 2832533051
Category : Medical
Languages : en
Pages : 138
Book Description
Publisher: Frontiers Media SA
ISBN: 2832533051
Category : Medical
Languages : en
Pages : 138
Book Description
Perioperative Medicine
Author: Mark F. Newman, MD
Publisher: Elsevier Health Sciences
ISBN: 1416024565
Category : Medical
Languages : en
Pages : 744
Book Description
Recognized authorities in anesthesiology and surgical critical care present you with today's best management approaches for achieving optimal perioperative outcomes. They review the potential risks to all major organ systems by examining the incidence and significance of organ dysfunction...assessing the etiology of particular organ dysfunctions...defining the preoperative and intraoperative risk factors...and offering perioperative protection strategies to minimize potential complications. A consistent chapter format - combined with color-coded algorithms, summary tables and boxes - enable you to quickly locate specific guidance. Top evidence- and outcome-based strategies from leading world authorities enable you to avoid and manage complications. A consistent format allows you to easily and efficiently access the very latest research and clinical practice guidelines. Color-coded algorithms, as well as abundant summary tables and boxes, save you valuable time in locating the best management approaches.
Publisher: Elsevier Health Sciences
ISBN: 1416024565
Category : Medical
Languages : en
Pages : 744
Book Description
Recognized authorities in anesthesiology and surgical critical care present you with today's best management approaches for achieving optimal perioperative outcomes. They review the potential risks to all major organ systems by examining the incidence and significance of organ dysfunction...assessing the etiology of particular organ dysfunctions...defining the preoperative and intraoperative risk factors...and offering perioperative protection strategies to minimize potential complications. A consistent chapter format - combined with color-coded algorithms, summary tables and boxes - enable you to quickly locate specific guidance. Top evidence- and outcome-based strategies from leading world authorities enable you to avoid and manage complications. A consistent format allows you to easily and efficiently access the very latest research and clinical practice guidelines. Color-coded algorithms, as well as abundant summary tables and boxes, save you valuable time in locating the best management approaches.
The Chemotherapy Source Book
Author: Michael Clinton Perry
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781773287
Category : Medical
Languages : en
Pages : 820
Book Description
The Chemotherapy Source Book, Fourth Edition pulls together all the current information on the chemotherapeutic management of cancer patients, including choice of chemotherapeutic agents, use of combinations, and toxicity of individual drugs. Organized by disease site, the book brings together pharmacologic and patient management information in one source that clinicians can consult for any question encountered in the delivery of chemotherapy. This updated Fourth Edition includes new drugs as well as new indications for older drugs. Content has been streamlined to provide essential information more quickly for the busy practitioner. Plus, this edition is softcover for greater portability and convenience.
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781773287
Category : Medical
Languages : en
Pages : 820
Book Description
The Chemotherapy Source Book, Fourth Edition pulls together all the current information on the chemotherapeutic management of cancer patients, including choice of chemotherapeutic agents, use of combinations, and toxicity of individual drugs. Organized by disease site, the book brings together pharmacologic and patient management information in one source that clinicians can consult for any question encountered in the delivery of chemotherapy. This updated Fourth Edition includes new drugs as well as new indications for older drugs. Content has been streamlined to provide essential information more quickly for the busy practitioner. Plus, this edition is softcover for greater portability and convenience.
Disease Control Priorities, Third Edition (Volume 1)
Author: Haile T. Debas
Publisher: World Bank Publications
ISBN: 1464803676
Category : Medical
Languages : en
Pages : 445
Book Description
Essential Surgery is part of a nine volume series for Disease Control Priorities which focuses on health interventions intended to reduce morbidity and mortality. The Essential Surgery volume focuses on four key aspects including global financial responsibility, emergency procedures, essential services organization and cost analysis.
Publisher: World Bank Publications
ISBN: 1464803676
Category : Medical
Languages : en
Pages : 445
Book Description
Essential Surgery is part of a nine volume series for Disease Control Priorities which focuses on health interventions intended to reduce morbidity and mortality. The Essential Surgery volume focuses on four key aspects including global financial responsibility, emergency procedures, essential services organization and cost analysis.
Holland-Frei Cancer Medicine
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 1118934695
Category : Medical
Languages : en
Pages : 2003
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Publisher: John Wiley & Sons
ISBN: 1118934695
Category : Medical
Languages : en
Pages : 2003
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Surgical Management of Advanced Pelvic Cancer
Author: Desmond C. Winter
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Decision Making in Perioperative Medicine: Clinical Pearls
Author: Steven L. Cohn
Publisher: McGraw Hill Professional
ISBN: 1260468119
Category : Medical
Languages : en
Pages : 351
Book Description
Minimize risk for every surgery-bound patient with this concise, high-yield clinical reference “The accuracy and readability of this [book] is excellent... the writing style is appropriate, informative, and suitable for the primary care clinician. The topics are well researched [and] the clinical recommendations reflect the most current guidelines.”—Robert C. Lavender, MD, FACP “The editor and contributing authors are all highly credible authorities and experienced clinicians... This is an extremely well-written, evidence-based text that fills a real gap. It should be useful not only to its intended audience, but also to surgeons and surgical trainees who often provide the initial management of these situations in the absence of consultants.”—Doody’s Review Service With new surgical advances and innovations, more older, sicker, higher-risk patients are undergoing surgery. Expertly assessing and managing patients with comorbidities who are undergoing surgical procedures is an absolutely critical task today—and Decision Making in Perioperative Medicine: Clinical Pearls will ensure that you make the right decisions through every step of the process. Which risk calculator should you use? How long should you delay surgery after percutaneous coronary intervention? Should the patient continue taking aspirin? How long before surgery should you stop a direct-acting oral anticoagulant? Decision Making in Perioperative Medicine: Clinical Pearls answers your questions when it comes to perioperative care. Filled with algorithms, tables, and clinical pearls, this practical resource is organized into three sections: Key takeaways on preoperative evaluation, testing, anesthesia, and medication management Expert guidance on evaluating the effect of comorbidities on surgical outcome and providing strategies for medical optimization to minimize risk Review of common postoperative medical complications and treatment Whether you’re a hospitalist, internist, family physician, anesthesiologist, physician assistant, or nurse practitioner, Decision Making in Perioperative Medicine: Clinical Pearls provides the evidence-based information and insights you need to make sure every surgery-bound patient receives the quality of care and management they deserve.
Publisher: McGraw Hill Professional
ISBN: 1260468119
Category : Medical
Languages : en
Pages : 351
Book Description
Minimize risk for every surgery-bound patient with this concise, high-yield clinical reference “The accuracy and readability of this [book] is excellent... the writing style is appropriate, informative, and suitable for the primary care clinician. The topics are well researched [and] the clinical recommendations reflect the most current guidelines.”—Robert C. Lavender, MD, FACP “The editor and contributing authors are all highly credible authorities and experienced clinicians... This is an extremely well-written, evidence-based text that fills a real gap. It should be useful not only to its intended audience, but also to surgeons and surgical trainees who often provide the initial management of these situations in the absence of consultants.”—Doody’s Review Service With new surgical advances and innovations, more older, sicker, higher-risk patients are undergoing surgery. Expertly assessing and managing patients with comorbidities who are undergoing surgical procedures is an absolutely critical task today—and Decision Making in Perioperative Medicine: Clinical Pearls will ensure that you make the right decisions through every step of the process. Which risk calculator should you use? How long should you delay surgery after percutaneous coronary intervention? Should the patient continue taking aspirin? How long before surgery should you stop a direct-acting oral anticoagulant? Decision Making in Perioperative Medicine: Clinical Pearls answers your questions when it comes to perioperative care. Filled with algorithms, tables, and clinical pearls, this practical resource is organized into three sections: Key takeaways on preoperative evaluation, testing, anesthesia, and medication management Expert guidance on evaluating the effect of comorbidities on surgical outcome and providing strategies for medical optimization to minimize risk Review of common postoperative medical complications and treatment Whether you’re a hospitalist, internist, family physician, anesthesiologist, physician assistant, or nurse practitioner, Decision Making in Perioperative Medicine: Clinical Pearls provides the evidence-based information and insights you need to make sure every surgery-bound patient receives the quality of care and management they deserve.
Preoperative (Neoadjuvant) Chemotherapy
Author: Joseph Ragaz
Publisher: Springer Science & Business Media
ISBN: 3642826717
Category : Medical
Languages : en
Pages : 172
Book Description
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.
Publisher: Springer Science & Business Media
ISBN: 3642826717
Category : Medical
Languages : en
Pages : 172
Book Description
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.