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Author: National Research Council
Publisher: National Academies Press
ISBN: 0309181356
Category : Science
Languages : en
Pages : 276
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Book Description
Perchlorateâ€"a powerful oxidant used in solid rocket fuels by the military and aerospace industryâ€"has been detected in public drinking water supplies of over 11 million people at concentrations of at least 4 parts per billion (ppb). High doses of perchlorate can decrease thyroid hormone production by inhibiting the uptake of iodide by the thyroid. Thyroid hormones are critical for normal growth and development of the central nervous system of fetuses and infants. This report evaluates the potential health effects of perchlorate and the scientific underpinnings of the 2002 draft risk assessment issued by the U.S. Environmental Protection Agency (EPA). The report finds that the body can compensate for iodide deficiency, and that iodide uptake would likely have to be reduced by at least 75% for months or longer for adverse health effects, such as hypothryroidism, to occur. The report recommends using clinical studies of iodide uptake in humans as the basis for determining a reference dose rather than using studies of adverse health effects in rats that serve as EPA's basis. The report suggests that daily ingestion of 0.0007 milligrams of perchlorate per kilograms of body weightâ€"an amount more than 20 times the reference dose proposed by EPAâ€"should not threaten the health of even the most sensitive populations.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309181356
Category : Science
Languages : en
Pages : 276
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Book Description
Perchlorateâ€"a powerful oxidant used in solid rocket fuels by the military and aerospace industryâ€"has been detected in public drinking water supplies of over 11 million people at concentrations of at least 4 parts per billion (ppb). High doses of perchlorate can decrease thyroid hormone production by inhibiting the uptake of iodide by the thyroid. Thyroid hormones are critical for normal growth and development of the central nervous system of fetuses and infants. This report evaluates the potential health effects of perchlorate and the scientific underpinnings of the 2002 draft risk assessment issued by the U.S. Environmental Protection Agency (EPA). The report finds that the body can compensate for iodide deficiency, and that iodide uptake would likely have to be reduced by at least 75% for months or longer for adverse health effects, such as hypothryroidism, to occur. The report recommends using clinical studies of iodide uptake in humans as the basis for determining a reference dose rather than using studies of adverse health effects in rats that serve as EPA's basis. The report suggests that daily ingestion of 0.0007 milligrams of perchlorate per kilograms of body weightâ€"an amount more than 20 times the reference dose proposed by EPAâ€"should not threaten the health of even the most sensitive populations.
Author:
Publisher:
ISBN:
Category : Perchloric acid
Languages : en
Pages : 278
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Book Description
Author: Lawrence E. Matthews
Publisher: Nova Science Publishers
ISBN: 9781617618123
Category : Perchlorates
Languages : en
Pages : 0
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Book Description
Perchlorates are the salts derived from perchloric acid (HClO4). They occur both naturally and through manufacturing. They have been used as a medicine for more than 50 years to treat thyroid gland disorders and are used extensively within the pyrotechnics industry, and ammonium perchlorate is also a component of solid rocket fuel. This book presents current research data from across the globe in the study of perchlorates, their production, uses, and health effects. Some topics discussed, herein, are: trends in the study of the electrochemical stability of perchlorate ions; the structural and vibrational properties of chromyl perchlorate; perchlorate formation in electrochemical water disinfection; metal perchlorates as Lewis acids; alkaline earth metal perchlorates; and removal of perchlorate from water.
Author: Edward Todd Urbansky
Publisher: Springer Science & Business Media
ISBN: 1461543037
Category : Science
Languages : en
Pages : 299
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Book Description
Based on a symposium sponsored by the Environmental Division of the American Chemical Society, Perchlorate in the Environment is the first comprehensive book to address perchlorate as a potable water contaminant. The two main topics are: analytical chemistry (focusing on ion chromatography and electrospray ionization mass spectrometry), and treatment or remediation. Also included are topics such as ion exchange, phytoremediation, bacterial reduction of perchlorate, bioreactors, and in situ bioremediation. To provide complete coverage, background chapters on fundamental chemistry, toxicology, and reulatory issues are also included. The authors are environmental consultants, government researchers, industry experts, and university professors from a wide array of disciplines.
Author: GEORGE FREDERICK SMITH
Publisher:
ISBN:
Category :
Languages : en
Pages : 164
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Book Description
Author:
Publisher:
ISBN:
Category : Health risk assessment
Languages : en
Pages : 276
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Book Description
Author: Parmalee Shirley Haugsrud
Publisher:
ISBN:
Category : Furfural
Languages : en
Pages : 130
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Book Description
Author: Kathleen Sellers
Publisher: CRC Press
ISBN: 9780849380815
Category : Technology & Engineering
Languages : en
Pages : 258
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Book Description
The development of analytical methods for identifying widespread perchlorate contamination brought about an explosion of research into the environmental problems and their potential solutions along with a corresponding increase in the availability of information. Unlike reference works that focus on only a few aspects of this contaminant, Perchlorate: Environmental Problems and Solutions offers a comprehensive, single source of information on perchlorate contamination in the environment. Summarizing the state of the science and developments in engineering, the book describes: Common sources of perchlorate Its behavior in the environment Methods for analyzing perchlorate in environmental samples Potential risks to human health and the environment Regulatory standards and criteria Techniques for remediating environmental contamination The authors illustrate these points with case studies of perchlorate contamination in soil, groundwater, and surface water. These case studies provide perspective on issues commonly faced by scientists, engineers, and managers of perchlorate-impacted sites. Organized to follow the logical sequence of identifying and solving contamination problems, the book provides the foundation necessary to understand perchlorate's occurrence, environmental behavior, regulatory status, and remediation.
Author:
Publisher:
ISBN:
Category : Subject headings
Languages : en
Pages : 288
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Book Description
Author: U.S. Atomic Energy Commission
Publisher:
ISBN:
Category : Subject headings
Languages : en
Pages : 346
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Book Description
