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Author: Awanish Kumar
Publisher: Elsevier
ISBN: 044315242X
Category : Science
Languages : en
Pages : 194
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Book Description
Pathogenic Viruses and Armamentarium Design covers the latest developments in viral target elucidation and viral control using wet and dry lab strategies. The control and combat strategies and their implementation compiled in this book are a valuable aid in understanding viral disease progression and designing new strategies against existing and evolving viruses. This important resource is a comprehensive compilation of anti-viral approaches designed and devised using computational and other laboratory techniques. The content targets the readership of college students, scientists and research investigators working on the pathogenic virus and development of prophylactics and therapeutics against viral infection. Researchers from biotechnology, infection biology, chemistry and pharmaceutical science will surely benefit from this content. The incorporation of software and tools will also help both experienced and new bioinformaticians and students. - Provides an overview of human pathogenic viruses, viral entry and disease progression, and strategic approaches to combating existing and evolving viruses - Explores available techniques for clinical diagnostics, virology, and viral immune diagnostics - Comprehensively discusses antiviral drugs, their targets, mechanism of action, design, and development challenges
Author: Awanish Kumar
Publisher: Elsevier
ISBN: 044315242X
Category : Science
Languages : en
Pages : 194
Get Book Here
Book Description
Pathogenic Viruses and Armamentarium Design covers the latest developments in viral target elucidation and viral control using wet and dry lab strategies. The control and combat strategies and their implementation compiled in this book are a valuable aid in understanding viral disease progression and designing new strategies against existing and evolving viruses. This important resource is a comprehensive compilation of anti-viral approaches designed and devised using computational and other laboratory techniques. The content targets the readership of college students, scientists and research investigators working on the pathogenic virus and development of prophylactics and therapeutics against viral infection. Researchers from biotechnology, infection biology, chemistry and pharmaceutical science will surely benefit from this content. The incorporation of software and tools will also help both experienced and new bioinformaticians and students. - Provides an overview of human pathogenic viruses, viral entry and disease progression, and strategic approaches to combating existing and evolving viruses - Explores available techniques for clinical diagnostics, virology, and viral immune diagnostics - Comprehensively discusses antiviral drugs, their targets, mechanism of action, design, and development challenges
Author: Michael F. Powell
Publisher: Springer
ISBN: 1461518237
Category : Medical
Languages : en
Pages : 977
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Book Description
When my interest was first drawn to the phenomenon of vaccination for virus diseases in the late 1930s, the state of the art and the science of vaccine design was not far advanced beyond the time of Jenner at the end of the 18th century and of Pasteur a century later. In the 1930s it was still believed that for the induction of immunity to a virus-caused disease the experience of infection was required, but not for a toxin-caused disease such as diphtheria or tetanus, for which a chemically detoxified antigen was effective for immu nization. This prompted the question as to whether it might be possible to produce a similar effect for virus diseases using nonreplicating antigens. When in the 1930s and 1940s it was found possible to propagate influenza viruses in the chick embryo, protective effects could be induced without the need to experience infection by the use of a sufficient dose of a noninfectious influenza virus preparation. Later in the 1940s, it became possible to propagate polio and other viruses in cultures of human and monkey tissue and to immunize against other virus diseases in the same way. Later, with the advent of the era of molecular biology and genetic engineering, antigens and vaccines could be produced in new and creative ways, using either replicating or nonreplicating forms of the appropriate antigens for inducing a dose-related protective state.
Author: P. W. Andrew
Publisher: John Wiley & Sons
ISBN: 047069520X
Category : Science
Languages : en
Pages : 287
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Book Description
The 20th century has seen improvements in both public health and disease prevention which, in turn, have had a dramatic impact on our lives. Success in preventing infection by vaccination and treating infection with antibiotics led some to believe that infectious disease was a thing of the past. However, the adaptability of pathogens and the emergence of new diseases has presented microbiologists with a fresh set of challenges as we enter the new millennium. While celebrating past successes and highlighting developing problems, this volume aims to address some of the issues facing microbiologists in the future. Covering a wide range of topics, it will provide an invaluable resource for microbiologists and an excellent reference for advanced students.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309314003
Category : Medical
Languages : en
Pages : 310
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Book Description
In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.
Author: David T. Curiel
Publisher: Academic Press
ISBN: 0128005106
Category : Science
Languages : en
Pages : 870
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Book Description
Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. - Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors - Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement - Demonstrates noninvasive imaging of adenovirus-mediated gene transfer - Discusses utility of adenoviral vectors in animal disease models - Considers Federal Drug Administration regulations for human clinical trials
Author: King K. Holmes
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 1027
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Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author: Moulay Mustapha Ennaji
Publisher: Academic Press
ISBN: 0128149671
Category : Science
Languages : en
Pages : 389
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Book Description
Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control. - Covers most emerging viral disease in humans, animals and plants - Provides the most advanced tools and techniques in molecular virology and the modeling of viruses - Creates awareness that the appearance of new transmissible pathogens is a global risk - Highlights the need to adopt shared policies for the prevention and control of infectious diseases
Author: Fabrice Chretien
Publisher: John Wiley & Sons
ISBN: 1119467764
Category : Medical
Languages : en
Pages : 565
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Book Description
Highly commended at the British Medical Association (BMA) Awards 2019, this new volume from the International Society of Neuropathology series addresses infections of the nervous system, written by expert editors. An expansive and inclusive contents list including rare disorders presented in easily referable chapters, containing; definitions, microbiological characteristics, epidemiology, clinical features, lab tests, pathology, genetics and treatment.
Author: N. James Maclachlan
Publisher: Academic Press
ISBN: 012801170X
Category : Medical
Languages : en
Pages : 603
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Book Description
Fenner's Veterinary Virology, Fifth Edition, is a comprehensive reference of global importance that features coverage on viral agents, viral diseases of animals, and newly emerging viral zoonotic diseases. It is an excellent first port of call for researchers and students alike, presenting the fundamental principles of virology, virus structure, genome replication, and viral diseases, while also focusing on the topics' clinical aspects. Organized on a taxonomic basis, readers can quickly understand how the virus (or the viral diseases) fits into the bigger picture of the virus genus and family. The basic information about each virus, such as disease, transmission, control, and treatment are useful for veterinary students and clinicians for their practices in disease management and prevention. - Revised and updated to include taxonomic organization changes and topical information - Provides a comprehensive overview of viruses and viral diseases of veterinary significance - Includes global contributions from thought leaders - Emphasizes new and emerging viral diseases
Author: John E. Bennett, MD, MACP
Publisher: Elsevier Health Sciences
ISBN: 1455748013
Category : Medical
Languages : en
Pages : 5094
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Book Description
After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
