Part One: Modulation of Protein-ligand Interaction Through Synthetic Bifunctional Molecules and Endogenous Proteins; Part Two: Efforts Towards Elucidation of Microtubule-derived Signal Transduction and the Mechanism of Taxol

Part One: Modulation of Protein-ligand Interaction Through Synthetic Bifunctional Molecules and Endogenous Proteins; Part Two: Efforts Towards Elucidation of Microtubule-derived Signal Transduction and the Mechanism of Taxol PDF Author: Gregory Thomas Ray
Publisher:
ISBN:
Category :
Languages : en
Pages : 414

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Small Molecule Modulation of Protein-protein Interactions

Small Molecule Modulation of Protein-protein Interactions PDF Author: Joseph William Barco
Publisher:
ISBN:
Category :
Languages : en
Pages : 376

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Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 834

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Directory of Graduate Research

Directory of Graduate Research PDF Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 1846

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Book Description
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Signaling and the Cytoskeleton

Signaling and the Cytoskeleton PDF Author: Kermit L. Carraway
Publisher: Springer Science & Business Media
ISBN: 3662129930
Category : Science
Languages : en
Pages : 293

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Book Description
This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

Regenerative Pharmacology

Regenerative Pharmacology PDF Author: George J. Christ
Publisher: Cambridge University Press
ISBN: 0521899494
Category : Medical
Languages : en
Pages : 361

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Book Description
A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.

Concepts and Principles of Pharmacology

Concepts and Principles of Pharmacology PDF Author: James E. Barrett
Publisher: Springer Nature
ISBN: 3030353621
Category : Medical
Languages : en
Pages : 466

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Book Description
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

RAS Family GTPases

RAS Family GTPases PDF Author: Channing Der
Publisher: Springer
ISBN: 9781402043284
Category : Medical
Languages : en
Pages : 0

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Book Description
Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons. This book features chapters contributed by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.

Nanocarrier Technologies

Nanocarrier Technologies PDF Author: M. Reza Mozafari
Publisher: Springer Science & Business Media
ISBN: 1402050410
Category : Medical
Languages : en
Pages : 238

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Book Description
Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies. It is the first book with this topic. It comprises a collection of scientific articles from top research people in the field and provides an up-to-date source containing recent citation and bibliography. The book is an indispensable source of information for new researchers and scientists.

Innovations for Next-Generation Antibody-Drug Conjugates

Innovations for Next-Generation Antibody-Drug Conjugates PDF Author: Marc Damelin
Publisher: Springer
ISBN: 3319781545
Category : Medical
Languages : en
Pages : 358

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Book Description
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.