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Author: Luis M. de Pablos
Publisher: Humana
ISBN: 9781071616802
Category : Medical
Languages : en
Pages : 336
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Book Description
This detailed book provides a comprehensive series of innovative research techniques and methodologies applied to the parasite genomics research area, all applying different approaches to analyzing parasite genomes and furthering the study of genetic complexity and the mechanisms of regulation. Beginning with chapters on novel sequencing and the bioinformatics pipeline, the volume continues by exploring diagnostic approaches using genomic tools, host-parasite interactions, as well as the genomics of parasite-derived extracellular vesicles. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics: Methods and Protocols creates a detailed picture of genomic approaches for researchers seeking a better understanding of characterizing parasite nucleic acid content.
Author: Luis M. de Pablos
Publisher: Humana
ISBN: 9781071616802
Category : Medical
Languages : en
Pages : 336
Get Book Here
Book Description
This detailed book provides a comprehensive series of innovative research techniques and methodologies applied to the parasite genomics research area, all applying different approaches to analyzing parasite genomes and furthering the study of genetic complexity and the mechanisms of regulation. Beginning with chapters on novel sequencing and the bioinformatics pipeline, the volume continues by exploring diagnostic approaches using genomic tools, host-parasite interactions, as well as the genomics of parasite-derived extracellular vesicles. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics: Methods and Protocols creates a detailed picture of genomic approaches for researchers seeking a better understanding of characterizing parasite nucleic acid content.
Author: Sara E. Melville
Publisher: Springer Science & Business Media
ISBN: 1592597939
Category : Science
Languages : en
Pages : 454
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Book Description
Parasitic diseases remain a major health problem throughout the world, for both humans and animals. For many of us, our technologically advanced lifestyle has decreased the prevalence and transmission of parasitic diseases, but for the majority of the world’s population, they are ever present in homes, domestic animals, food, or the environment. The study of parasites and parasitic disease has a long and distinguished history. In some cases, it has been driven by the great importance of the presence of the parasite to the community, for example, those that affect our livestock. In other cases, it is clear that applied research has suffered for lack of funding because the parasite affects people with few resources, such as the rural poor in resource-poor countries. These instances include the so-called “neglected diseases,” as defined by the World Health Organization (WHO). Parasites have complicated life cycles, and a thorough understanding of the unique characteristics of a particular parasite species is vital in attempts to avoid, prevent, or cure infection or to alleviate symptoms. Of course, the biological characteristics that each parasite has developed to aid survival and transmission, to avoid destruction by the immune system, and to adapt to a changing environment are of lasting fascination to basic biologists as well. The elegance of these biological systems has ensured that the study of protozoan and metazoan parasites also remains an active field of research in countries where the diseases are not a threat to the population.
Author: George Robert Coatney
Publisher:
ISBN:
Category : Malaria
Languages : en
Pages : 388
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Book Description
Author: David P. Hughes
Publisher: Oxford University Press
ISBN: 0199642230
Category : Science
Languages : en
Pages : 247
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Book Description
Parasites that manipulate the behaviour of their hosts represent striking examples of adaptation by natural selection. This text provides an authoritative review of host manipulation by parasites that assesses developments in the field and lays out a framework for future research.
Author: Paul Schmid-Hempel
Publisher: Oxford University Press
ISBN: 0192568159
Category : Medical
Languages : en
Pages : 572
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Book Description
Parasites and infectious diseases are everywhere and represent some of the most potent forces shaping the natural world. They affect almost every aspect imaginable in the life of their hosts, even as far as the structure of entire ecosystems. Hosts, in turn, have evolved complex defences, with immune systems being among the most sophisticated processes known in nature. In response, parasites have again found ways to manipulate and exploit their hosts. Ever since life began, hosts and parasites have taken part in this relentless co-evolutionary struggle with far-reaching consequences for us all. Today, concepts borrowed from evolution, ecology, parasitology, and immunology have formed a new synthesis for the study of host-parasite interactions. Evolutionary parasitology builds on these established fields of scientific enquiry but also includes some of the most successful inter-disciplinary areas of modern biology such as evolutionary epidemiology and ecological immunology. The first edition of this innovative text quickly became the standard reference text for this new discipline. Since then, the field has progressed rapidly and an update is now required. This new edition has been thoroughly revised to provide a state-of-the-art overview, from the molecular bases to adaptive strategies and their ecological and evolutionary consequences. It includes completely new material on topics such as microbiota, evolutionary genomics, phylodynamics, within-host evolution, epidemiology, disease spaces, and emergent diseases. Evolutionary Parasitology is suitable for advanced undergraduates, graduate level students, and interdisciplinary researchers from a variety of fields including immunology, genetics, sexual selection, population ecology, behavioural ecology, epidemiology, and evolutionary biology. Those studying and working in adjacent fields such as conservation biology, virology, medicine, and public health will also find it an invaluable resource for connecting to the bases of their science.
Author: Aaron G. Maule
Publisher: CABI
ISBN: 1845930398
Category : Science
Languages : en
Pages : 470
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Book Description
Parasitic flatworms include Cestodes (tapeworms) and trematodes (flukes, schistosomes, etc) and are the cause of a number of major diseases of medical and veterinary significance. Much recent research has focused on molecular biology and genomics. this book aims to review advances in our understanding of these and related topics such as flatworm biochemistry, immunology and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-living species. Contributors to the book include leading authorities from Europe, North and South America, and Australia.
Author: Eric Loker
Publisher: Garland Science
ISBN: 1317407725
Category : Medical
Languages : en
Pages : 577
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Book Description
Parasitology: A Conceptual Approach focuses on the conceptual basis of parasitology, with the goal of providing students with an enriched view of parasites and their biology. Concentrating on concepts will enable readers to gain a broader perspective that will increase their ability to think critically about all kinds of parasitic associations. The interfaces between the study of parasitism and prominent biological disciplines such as biodiversity, immunology, ecology, evolution, conservation biology, and disease control are highlighted. Studying individual parasites is an essential part of parasitology so Parasitology: A Conceptual Approach contains an appendix which provides a concise overview of the biology of important human and veterinary parasites. End-of-chapter questions are provided, as is an instructor manual.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309180716
Category : Science
Languages : en
Pages : 102
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Book Description
The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.
Author: Serge Morand
Publisher: Cambridge University Press
ISBN: 1107037654
Category : Medical
Languages : en
Pages : 503
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Book Description
By joining phylogenetics and evolutionary ecology, this book explores the patterns of parasite diversity while revealing diversification processes.
Author: Jong-Yil Chai
Publisher: Springer Nature
ISBN: 9402417044
Category : Medical
Languages : en
Pages : 555
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Book Description
This book provides up-to-date information on the characteristics of each species of intestinal fluke found in humans and on the management of infections caused by these trematodes. Biology, epidemiology, host-parasite relationships, pathogenicity, clinical aspects, diagnosis, and treatment are all reviewed in detail. The zoonotic intestinal flukes comprise 38 genera belonging to 16 families. They are morphologically diverse and each species has a characteristic life cycle and geographical distribution. Intestinal fluke infections are commonly considered as tropical endemic diseases in Asian countries, where 6 million people are infected, but the geographical limits and populations at risk are expanding and changing owing to a range of factors, including growing international markets, improved transportation systems, changes in eating habits, demographic trends, and climate change. While the pathogenicity of intestinal flukes is generally mild, the impact in immunocompromised individuals requires clarification and some diagnostic problems remain to be solved. In exploring all aspects of human intestinal fluke infections, this book will be invaluable for clinicians and researchers alike.
