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Author: Jeffrey Steven Mogil
Publisher: Progress in Pain Research and
ISBN:
Category : Medical
Languages : en
Pages : 376
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Book Description
Genetics more than any other biological approach can explain why some people experience more pain than others and receive less benefit from existing analgesics. Sixteen scholarly articles from international contributors describe the application of genetic techniques to the problem of pain and consider the knowledge that has so far resulted. Three themed sections review the techniques that are allowing the study of pain mechanisms at the genetic level; describe the progress being made in lab animals and humans in identifying the genes responsible for individual differences; and explore the practical and ethical issues that face pain researchers. The editor is associated with the Centre for Research on Pain, McGill U., Montreal. Annotation : 2004 Book News, Inc., Portland, OR (booknews.com).
Author: Jeffrey Steven Mogil
Publisher: Progress in Pain Research and
ISBN:
Category : Medical
Languages : en
Pages : 376
Get Book Here
Book Description
Genetics more than any other biological approach can explain why some people experience more pain than others and receive less benefit from existing analgesics. Sixteen scholarly articles from international contributors describe the application of genetic techniques to the problem of pain and consider the knowledge that has so far resulted. Three themed sections review the techniques that are allowing the study of pain mechanisms at the genetic level; describe the progress being made in lab animals and humans in identifying the genes responsible for individual differences; and explore the practical and ethical issues that face pain researchers. The editor is associated with the Centre for Research on Pain, McGill U., Montreal. Annotation : 2004 Book News, Inc., Portland, OR (booknews.com).
Author: Stephen G. Waxman
Publisher: MIT Press
ISBN: 0262037408
Category : Medical
Languages : en
Pages : 320
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Book Description
A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire. Two soldiers, both with wounds injuring the same nerve, show very different responses: one is disabled by neuropathic pain, unable to touch the injured limb because even the lightest contact triggers excruciating discomfort; the other notices numbness but no pain at all. Could the difference lie in their genes? In this book, described in the foreword by Nobel Laureate James Rothman as “so well written that it reads like a detective novel,” Stephen Waxman recounts the search for a gene that controls pain—a search spanning more than thirty years and three continents. The story moves from genes to pain-signaling neurons that scream when they should be silent to people with a rare genetic disorder who feel they are on fire. Waxman explains that if pain-signaling neurons are injured by trauma or disease, they can become hyperactive and send pain signals to the brain even without external stimulus. Studying the hyperactive mutant pain gene in man on fire syndrome has pointed the way to molecules that produce pain more broadly within the general population, in the rest of us. Waxman's account of the many steps that led to discovery of the pain gene tells the story behind the science, of how science happens.
Author: Inna Belfer
Publisher: John Wiley & Sons
ISBN: 1118398858
Category : Science
Languages : en
Pages : 255
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Book Description
Pain Genetics: Basic to Translational Science is a timely synthesis of the key areas of research informing our understanding of the genetic basis of pain. The book opens with foundational information on basic genetic mechanisms underlying pain perception and progresses recently discovered complex concepts facing the field. The coverage is wide-ranging and will serves as an excellent entry point into understating the genetics of pain as well as providing a single resource for established researchers looking for a better understanding of the diverse strands of research going on in the area. With contributors painstakingly selected to provide a broad range of perspectives and research, Pain Genetics will be a valuable resource for geneticists, neuroscientists, and biomedical professionals alike.
Author: Gérard Mick
Publisher: Springer Science & Business Media
ISBN: 3319043226
Category : Medical
Languages : en
Pages : 175
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Book Description
Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.
Author: Inna Belfer
Publisher: John Wiley & Sons
ISBN: 9781118398845
Category : Science
Languages : en
Pages : 0
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Book Description
Pain Genetics: Basic to Translational Science is a timely synthesis of the key areas of research informing our understanding of the genetic basis of pain. The book opens with foundational information on basic genetic mechanisms underlying pain perception and progresses recently discovered complex concepts facing the field. The coverage is wide-ranging and will serves as an excellent entry point into understating the genetics of pain as well as providing a single resource for established researchers looking for a better understanding of the diverse strands of research going on in the area. With contributors painstakingly selected to provide a broad range of perspectives and research, Pain Genetics will be a valuable resource for geneticists, neuroscientists, and biomedical professionals alike.
Author: Wolfgang B. Liedtke, MD, PH.D.
Publisher: CRC Press
ISBN: 1420005847
Category : Medical
Languages : en
Pages : 502
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Book Description
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author: Marni Jackson
Publisher: A&C Black
ISBN: 1408830167
Category : Body, Mind & Spirit
Languages : en
Pages : 381
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Book Description
Why is pain so poorly understood? Why do we still distinguish between mental pain and physical pain, when pain is always an emotional experience? How can it be that science is about to clone a human being but still can't cure the pain of a bad back? If pain is the reason why most people visit the doctor, why are most doctors so bad at addressing the problem of suffering? Marni Jackson's PAIN: THE FIFTH VITAL SIGN is a witty, personal and groundbreaking inquiry into the nature, treatment and definition of human pain, one of the most misunderstood and elusive subjects to challenge humankind. In the questing and narrative manner of Oliver Sacks, Jackson takes us back into the history of pain and forward into the possibilities of pain genetics, Jackson brings us stories both of people in pain and the pain pioneers: eccentrics and artists, wrestlers and writers, psychologists and philosophers, nurses and doctors. Above all, Pain makes an elusive subject vivid and readable. We all know what pain is. Now Marni Jackson has given it a voice.
Author: G. Kuhlenbäumer
Publisher: Springer Science & Business Media
ISBN: 9783798514539
Category : Medical
Languages : en
Pages : 296
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Book Description
"Hereditary Peripheral Neuropathies" deals with the Charcot-Marie-Tooth group of neuropathies and related primary hereditary neuropathies. The knowledge in this field has grown exponentially during the last ten years. The book is divided into two sections. The first section deals with the clinical presentation, electrophysiological features and differential diagnosis of these disorders as well as with the general biology of the peripheral nerve. The second section gives a detailed account of the known disease entities. The book will be interesting for both the clinician with a special interest in PNS diseases as well as for the researcher.
Author: Lawrence Kruger
Publisher: CRC Press
ISBN: 1439812101
Category : Health & Fitness
Languages : en
Pages : 458
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Book Description
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Author: Emeran A. Mayer
Publisher: Lippincott Williams & Wilkins
ISBN: 1496332008
Category : Medical
Languages : en
Pages : 643
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Book Description
This book explores the connection of functional pain syndromes (e.g., irritable bowel syndrome and fibromyalgia) with anxiety, depression, chronic fatigue syndrome, and posttraumatic stress disorder. The authors address possible common pathophysiologies and review a range of treatment options, from antidepressants to cognitive-behavioral therapy. Who should buy this book? Whether you are a general practitioner, specialist, or scientist, this book is essential reading. It sheds new light on the complex links between various painful syndromes and disorders.
