Oxygen/Nitrogen Radicals: Cell Injury and Disease

Oxygen/Nitrogen Radicals: Cell Injury and Disease PDF Author: Val Vallyathan
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393

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Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Oxygen/Nitrogen Radicals: Cell Injury and Disease

Oxygen/Nitrogen Radicals: Cell Injury and Disease PDF Author: Val Vallyathan
Publisher: Springer Science & Business Media
ISBN: 1461510872
Category : Science
Languages : en
Pages : 393

Get Book

Book Description
A veritable mountain of literature has been published showing the causal relationship of reactive oxygen/nitrogen species in human disease conditions, and there has been an explosion in the understanding of oxidative stress, the protective role of antioxidants and molecular events involved in the regulation of transcription, editing, and translation of key events leading to disease processes. Strategies need to be developed for prevention of diseases by allowing scientists and clinicians to obtain information on new and emerging advances. The molecular mechanisms involved in several diseases including Alzheimer's disease, atherosclerosis, diabetes, arthritis, and Parkinson's disease, as well as disorders of the eye, skin, cardiac, and pulmonary systems are discussed in this volume, along with scientific evidence supporting the value of dietary supplementation with antioxidants in the prevention of cellular damage leading to chronic disease. Special in vivo techniques are also discussed at length, along with the role of molecular studies in human risk assessment.

Oxygen Nitrogen Radicals: Cell Injury and Disease

Oxygen Nitrogen Radicals: Cell Injury and Disease PDF Author: Val Vallyathan
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Oxygen Radicals and Lung Injury

Oxygen Radicals and Lung Injury PDF Author:
Publisher:
ISBN:
Category : Active oxygen
Languages : en
Pages : 244

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Book Description


Oxygen/Nitrogen Radicals and Cellular Injury

Oxygen/Nitrogen Radicals and Cellular Injury PDF Author: Kenneth B. Adler
Publisher: DIANE Publishing
ISBN: 0788185381
Category :
Languages : en
Pages : 142

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Book Description
Papers: characterization of inducible nitric oxide synthase expression in human airway epithelium; nitric oxide and its congeners in mitochondria; role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock; nitric oxide and peroxynitrite production in ocular inflammation; 5 papers on pulmonary/pollutant effects; 6 papers on oxidants and signal transduction, including impact of oxidative stress on signal transduction control by phosphotyrosine phosphatases; the nature of antioxidant defense mechanisms; lipid peroxidation products and antioxidants in human disease; and lung injury and oxidoreductases.

Oxygen/Nitrogen Radicals

Oxygen/Nitrogen Radicals PDF Author: Val Vallyathan
Publisher: CRC Press
ISBN: 9780824748746
Category : Medical
Languages : en
Pages : 550

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Book Description
The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.

Oxygen/nitrogen Radicals and Cellular Injury

Oxygen/nitrogen Radicals and Cellular Injury PDF Author: Kenneth B. Adler
Publisher:
ISBN:
Category : Antioxidants
Languages : en
Pages : 160

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Book Description


Oxygen/Nitrogen Radicals

Oxygen/Nitrogen Radicals PDF Author: Val Vallyathan
Publisher:
ISBN: 9780824754464
Category :
Languages : en
Pages : 550

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Book Description


Free Radical Mechanisms of Tissue Injury

Free Radical Mechanisms of Tissue Injury PDF Author: Mary Treinen Moslen
Publisher: CRC Press
ISBN: 9780849351617
Category : Science
Languages : en
Pages : 238

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Book Description
This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.

Antioxidants in Sport Nutrition

Antioxidants in Sport Nutrition PDF Author: Manfred Lamprecht
Publisher: CRC Press
ISBN: 1466567570
Category : Medical
Languages : en
Pages : 304

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Book Description
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Oxygen Free Radicals in Tissue Damage

Oxygen Free Radicals in Tissue Damage PDF Author: TARR,M.
Publisher: Springer Science & Business Media
ISBN: 1461598400
Category : Science
Languages : en
Pages : 306

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Book Description
Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.