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Author: Christos P. Kitsos
Publisher: Springer Science & Business Media
ISBN: 3642452876
Category : Mathematics
Languages : en
Pages : 104
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Book Description
This book tackles the Optimal Non-Linear Experimental Design problem from an applications perspective. At the same time it offers extensive mathematical background material that avoids technicalities, making it accessible to non-mathematicians: Biologists, Medical Statisticians, Sociologists, Engineers, Chemists and Physicists will find new approaches to conducting their experiments. The book is recommended for Graduate Students and Researchers.
Author: Christos P. Kitsos
Publisher: Springer Science & Business Media
ISBN: 3642452876
Category : Mathematics
Languages : en
Pages : 104
Get Book Here
Book Description
This book tackles the Optimal Non-Linear Experimental Design problem from an applications perspective. At the same time it offers extensive mathematical background material that avoids technicalities, making it accessible to non-mathematicians: Biologists, Medical Statisticians, Sociologists, Engineers, Chemists and Physicists will find new approaches to conducting their experiments. The book is recommended for Graduate Students and Researchers.
Author: Valerii V. Fedorov
Publisher: CRC Press
ISBN: 1439821526
Category : Mathematics
Languages : en
Pages : 398
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Book Description
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors' many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of
Author: Peter Goos
Publisher: John Wiley & Sons
ISBN: 1119976162
Category : Science
Languages : en
Pages : 249
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Book Description
"This is an engaging and informative book on the modern practice of experimental design. The authors' writing style is entertaining, the consulting dialogs are extremely enjoyable, and the technical material is presented brilliantly but not overwhelmingly. The book is a joy to read. Everyone who practices or teaches DOE should read this book." - Douglas C. Montgomery, Regents Professor, Department of Industrial Engineering, Arizona State University "It's been said: 'Design for the experiment, don't experiment for the design.' This book ably demonstrates this notion by showing how tailor-made, optimal designs can be effectively employed to meet a client's actual needs. It should be required reading for anyone interested in using the design of experiments in industrial settings." —Christopher J. Nachtsheim, Frank A Donaldson Chair in Operations Management, Carlson School of Management, University of Minnesota This book demonstrates the utility of the computer-aided optimal design approach using real industrial examples. These examples address questions such as the following: How can I do screening inexpensively if I have dozens of factors to investigate? What can I do if I have day-to-day variability and I can only perform 3 runs a day? How can I do RSM cost effectively if I have categorical factors? How can I design and analyze experiments when there is a factor that can only be changed a few times over the study? How can I include both ingredients in a mixture and processing factors in the same study? How can I design an experiment if there are many factor combinations that are impossible to run? How can I make sure that a time trend due to warming up of equipment does not affect the conclusions from a study? How can I take into account batch information in when designing experiments involving multiple batches? How can I add runs to a botched experiment to resolve ambiguities? While answering these questions the book also shows how to evaluate and compare designs. This allows researchers to make sensible trade-offs between the cost of experimentation and the amount of information they obtain.
Author: Friedrich Pukelsheim
Publisher: SIAM
ISBN: 0898716047
Category : Mathematics
Languages : en
Pages : 527
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Book Description
Optimal Design of Experiments offers a rare blend of linear algebra, convex analysis, and statistics. The optimal design for statistical experiments is first formulated as a concave matrix optimization problem. Using tools from convex analysis, the problem is solved generally for a wide class of optimality criteria such as D-, A-, or E-optimality. The book then offers a complementary approach that calls for the study of the symmetry properties of the design problem, exploiting such notions as matrix majorization and the Kiefer matrix ordering. The results are illustrated with optimal designs for polynomial fit models, Bayes designs, balanced incomplete block designs, exchangeable designs on the cube, rotatable designs on the sphere, and many other examples.
Author: B.K. Sinha
Publisher: Springer
ISBN: 8132217861
Category : Mathematics
Languages : en
Pages : 213
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Book Description
The book dwells mainly on the optimality aspects of mixture designs. As mixture models are a special case of regression models, a general discussion on regression designs has been presented, which includes topics like continuous designs, de la Garza phenomenon, Loewner order domination, Equivalence theorems for different optimality criteria and standard optimality results for single variable polynomial regression and multivariate linear and quadratic regression models. This is followed by a review of the available literature on estimation of parameters in mixture models. Based on recent research findings, the volume also introduces optimal mixture designs for estimation of optimum mixing proportions in different mixture models, which include Scheffé’s quadratic model, Darroch-Waller model, log- contrast model, mixture-amount models, random coefficient models and multi-response model. Robust mixture designs and mixture designs in blocks have been also reviewed. Moreover, some applications of mixture designs in areas like agriculture, pharmaceutics and food and beverages have been presented. Familiarity with the basic concepts of design and analysis of experiments, along with the concept of optimality criteria are desirable prerequisites for a clear understanding of the book. It is likely to be helpful to both theoreticians and practitioners working in the area of mixture experiments.
Author: Wim J. van der Linden
Publisher: Springer Science & Business Media
ISBN: 0387290540
Category : Social Science
Languages : en
Pages : 421
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Book Description
Wim van der Linden was just given a lifetime achievement award by the National Council on Measurement in Education. There is no one more prominent in the area of educational testing. There are hundreds of computer-based credentialing exams in areas such as accounting, real estate, nursing, and securities, as well as the well-known admissions exams for college, graduate school, medical school, and law school - there is great need on the theory of testing. This book presents the statistical theory and practice behind constructing good tests e.g., how is the first test item selected, how are the next items selected, and when do you have enough items.
Author: Luc Pronzato
Publisher: Springer Science & Business Media
ISBN: 1461463637
Category : Medical
Languages : en
Pages : 404
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Book Description
Design of Experiments in Nonlinear Models: Asymptotic Normality, Optimality Criteria and Small-Sample Properties provides a comprehensive coverage of the various aspects of experimental design for nonlinear models. The book contains original contributions to the theory of optimal experiments that will interest students and researchers in the field. Practitionners motivated by applications will find valuable tools to help them designing their experiments. The first three chapters expose the connections between the asymptotic properties of estimators in parametric models and experimental design, with more emphasis than usual on some particular aspects like the estimation of a nonlinear function of the model parameters, models with heteroscedastic errors, etc. Classical optimality criteria based on those asymptotic properties are then presented thoroughly in a special chapter. Three chapters are dedicated to specific issues raised by nonlinear models. The construction of design criteria derived from non-asymptotic considerations (small-sample situation) is detailed. The connection between design and identifiability/estimability issues is investigated. Several approaches are presented to face the problem caused by the dependence of an optimal design on the value of the parameters to be estimated. A survey of algorithmic methods for the construction of optimal designs is provided.
Author: Herman Chernoff
Publisher: SIAM
ISBN: 9781611970593
Category : Technology & Engineering
Languages : en
Pages : 124
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Book Description
An exploration of the interrelated fields of design of experiments and sequential analysis with emphasis on the nature of theoretical statistics and how this relates to the philosophy and practice of statistics.
Author: Sergey Ermakov
Publisher: Springer Science & Business Media
ISBN: 9780792336624
Category : Science
Languages : en
Pages : 218
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Book Description
This book is devoted to a new branch of experimental design theory called simulation experimental design. There are many books devoted either to the theory of experimental design or to system simulation techniques, but in this book an approach to combine both fields is developed. Especially the mathematical theory of such universal variance reduction techniques as splitting and Russian Roulette is explored. The book contains a number of results on regression design theory related to nonlinear problems, the E-optimum criterion and designs which minimize bias. Audience: This volume will be of value to readers interested in systems simulation, applied statistics and numerical methods with basic knowledge of applied statistics and linear algebra.
Author: Harvey Motulsky
Publisher: Oxford University Press
ISBN: 9780198038344
Category : Mathematics
Languages : en
Pages : 352
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Book Description
Most biologists use nonlinear regression more than any other statistical technique, but there are very few places to learn about curve-fitting. This book, by the author of the very successful Intuitive Biostatistics, addresses this relatively focused need of an extraordinarily broad range of scientists.
