Off Target: The captivating, disturbing new thriller from the author of The Waiting Rooms

Off Target: The captivating, disturbing new thriller from the author of The Waiting Rooms PDF Author: Eve Smith
Publisher: Orenda Books
ISBN: 1914585038
Category : Fiction
Languages : en
Pages : 376

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Book Description
When a one-night stand leads to a long-desired pregnancy, Susan will do anything to ensure her husband won't find out ... including the unthinkable. But when something horrendous is unleashed around the globe, her secret isn't the only thing that is no longer safe... 'An astute, well-researched and convincing novel of ideas' The Times 'If you could create a "perfect" baby through genetic engineering, would you? A disturbing and interesting thriller, perfect for book club discussions' Nina Pottell, Prima 'Provocative, pacy and scarily all-too-possible' Philippa East ––––––––––––An unthinkable decision A deadly mistake In an all-too-possible near future, when genetic engineering has become the norm for humans, not just crops, parents are prepared to take incalculable risks to ensure that their babies are perfect ... altering genes that may cause illness, and more... Susan has been trying for a baby for years, and when an impulsive one-night stand her dream come true, she'll do anything to keep her daughter and ensure her husband doesn't find out ... including the unthinkable. She believes her secret is safe. For now. But as governments embark on a perilous genetic arms race and children around the globe start experiencing a host of distressing symptoms – even taking their own lives – something truly horrendous is unleashed. Because those children have only one thing in common, and people are starting to ask questions... Bestselling author of The Waiting Rooms, Eve Smith returns with an authentic, startlingly thought-provoking, disturbing blockbuster of a thriller that provides a chilling glimpse of a future that's just one modification away... _____________ 'An effective thriller that will keep you hooked to the very end ... more than that, it's a nuanced, believable examination of how human genetic engineering might play out...' SFX Magazine 'A brilliantly chilling work of speculative fiction – a disturbing but all-too-possible vision of the near future, where each of us gets to play God. Superb!' Guy Morpuss 'Sharp, intelligent, frightening and original' NB Magazine 'An eerily prophetic near-future viewed through a compassionately anchoring lens ... As tempting and tantalising a read as the vision of the future it presents' SciFi Now 'This is what speculative fiction should be – plausible, pacy, and with a story that packs real emotional punch' Louise Mumford 'When a writer's work is compared to Michael Crichton's, there's reason to sit up and pay attention ... a cautionary tale that's full of thrills' LoveReading 'Eve Smith has done it again! A brilliant read' J.M. Hewitt 'One of the most exciting writers around ... master of the high-concept thriller' Chris McDonald Praise for The Waiting Rooms***** 'Combines the excitement of a medical thriller à la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews For fans of Emily St John Mandel, Robin Cook, Tess Gerritsen and Louise Doughty

Off Target: The captivating, disturbing new thriller from the author of The Waiting Rooms

Off Target: The captivating, disturbing new thriller from the author of The Waiting Rooms PDF Author: Eve Smith
Publisher: Orenda Books
ISBN: 1914585038
Category : Fiction
Languages : en
Pages : 376

Get Book Here

Book Description
When a one-night stand leads to a long-desired pregnancy, Susan will do anything to ensure her husband won't find out ... including the unthinkable. But when something horrendous is unleashed around the globe, her secret isn't the only thing that is no longer safe... 'An astute, well-researched and convincing novel of ideas' The Times 'If you could create a "perfect" baby through genetic engineering, would you? A disturbing and interesting thriller, perfect for book club discussions' Nina Pottell, Prima 'Provocative, pacy and scarily all-too-possible' Philippa East ––––––––––––An unthinkable decision A deadly mistake In an all-too-possible near future, when genetic engineering has become the norm for humans, not just crops, parents are prepared to take incalculable risks to ensure that their babies are perfect ... altering genes that may cause illness, and more... Susan has been trying for a baby for years, and when an impulsive one-night stand her dream come true, she'll do anything to keep her daughter and ensure her husband doesn't find out ... including the unthinkable. She believes her secret is safe. For now. But as governments embark on a perilous genetic arms race and children around the globe start experiencing a host of distressing symptoms – even taking their own lives – something truly horrendous is unleashed. Because those children have only one thing in common, and people are starting to ask questions... Bestselling author of The Waiting Rooms, Eve Smith returns with an authentic, startlingly thought-provoking, disturbing blockbuster of a thriller that provides a chilling glimpse of a future that's just one modification away... _____________ 'An effective thriller that will keep you hooked to the very end ... more than that, it's a nuanced, believable examination of how human genetic engineering might play out...' SFX Magazine 'A brilliantly chilling work of speculative fiction – a disturbing but all-too-possible vision of the near future, where each of us gets to play God. Superb!' Guy Morpuss 'Sharp, intelligent, frightening and original' NB Magazine 'An eerily prophetic near-future viewed through a compassionately anchoring lens ... As tempting and tantalising a read as the vision of the future it presents' SciFi Now 'This is what speculative fiction should be – plausible, pacy, and with a story that packs real emotional punch' Louise Mumford 'When a writer's work is compared to Michael Crichton's, there's reason to sit up and pay attention ... a cautionary tale that's full of thrills' LoveReading 'Eve Smith has done it again! A brilliant read' J.M. Hewitt 'One of the most exciting writers around ... master of the high-concept thriller' Chris McDonald Praise for The Waiting Rooms***** 'Combines the excitement of a medical thriller à la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews For fans of Emily St John Mandel, Robin Cook, Tess Gerritsen and Louise Doughty

Off Target

Off Target PDF Author: Jill Ammon Vanderwood
Publisher: Human Rights Watch
ISBN:
Category : Juvenile Nonfiction
Languages : en
Pages : 134

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Book Description
What would you do if your friend showed you a gun?You are new in town and it's your first day at a new school. Your neighbor, Trevor introduces you to a group of three boys and two girls. Right away you notice that Eric, one of the guys in the group, is being bullied at school. When you go to Eric's house with your new friends, he shows the group a fully loaded handgun that is left in his mother's nightstand. You are faced with some hard choices when someone suggests that Eric should take the gun to school.___________________________________________What should you do? It's time to choose a path: If you're worried that Eric will take the gun to school-continue on page 7.If you decide to take the gun to prevent anyone from being hurt-continue on page 9.If you leave the house with the others and plan to come back for target practice the next day-continue on page 10.____________________________________________Off Target is the first book in The Path You Choose series. You, the reader determine the outcome by the choices you make. Once you read one story, go back and choose a different story. There are thirteen possible endings in this book.What path will you choose

The Waiting Rooms

The Waiting Rooms PDF Author: Eve Smith
Publisher: Orenda Books
ISBN: 1913193276
Category : Fiction
Languages : en
Pages : 400

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Book Description
Swinging from South Africa to England: one woman's hunt for her birth mother in an all-too-believable near future in which an antibiotic crisis has decimated the population. A prescient, thrilling debut. 'Combines the excitement of a medical thriller à la Michael Crichton with sensitive characterisation and social insight in a timely debut novel all the more remarkable for being conceived and written before the current pandemic' Guardian 'STUNNING and terrifying ... The Waiting Rooms wrenches your heart in every way possible, but written with such humanity and emotion' Miranda Dickinson 'Chillingly close to reality, this gripping thriller brims with authenticity ... a captivating, accomplished and timely debut from an author to watch' Adam Hamdy ________________ Decades of spiralling drug resistance have unleashed a global antibiotic crisis. Ordinary infections are untreatable, and a scratch from a pet can kill. A sacrifice is required to keep the majority safe: no one over seventy is allowed new antibiotics. The elderly are sent to hospitals nicknamed 'The Waiting Rooms' ... hospitals where no one ever gets well. Twenty years after the crisis takes hold, Kate begins a search for her birth mother, armed only with her name and her age. As Kate unearths disturbing facts about her mother's past, she puts her family in danger and risks losing everything. Because Kate is not the only secret that her mother is hiding. Someone else is looking for her, too. Sweeping from an all-too-real modern Britain to a pre-crisis South Africa, The Waiting Rooms is epic in scope, richly populated with unforgettable characters, and a tense, haunting vision of a future that is only a few mutations away. ________________ 'Engrossing and eye-opening, with heart-stopping plot twists ... a stunning medical thriller set in a terrifying possible future' Foreword Reviews 'A touching, gut-wrenching story of family mystery and tragedy ... a thriller that punches on two fronts – heart AND mind' The Sun 'Gripping and disturbing ... the medical research is convincing, the scenarios plausible, and the story is emotionally engaging. This is an incredible debut!' Gill Paul 'If the themes are dark and topical, the writing is exquisite. Breath held, I got to the finale with my heart in my mouth. Eve Smith weaves a complex and clever tale, merging countries and timelines; the result is a superb and satisfying novel' Louise Beech 'Margaret Atwood is one of my all-time writing heroes and The Handmaid's Tale is probably the best book I've ever read. Eve Smith and The Waiting Rooms really do challenge that long-held crown...' Random Things through My Letterbox 'Thoroughly engaging ... an eye-opening read' Crime Fiction Lover 'A novel of our times' Trip Fiction 'Haunting, honest and horrifying in its reality ... An epic and thrilling read' Book Literati 'Stunning dystopian debut. A prescient and alarming tale that seems just a whisper from reality' Suzy Apsley ' The Waiting Rooms will certainly distract us from the real world for a few hours and this is the immeasurable value of fiction. It gives hope that, as in Eve Smith's fictitious world, the possibility of a happy ending still exists' Die Burger ' The Waiting Rooms is a seriously impressive debut, a novel that is intuitive and chilling, one that will resonate with all in this current climate' Swirl & Thread

Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants PDF Author: Yvonne Will
Publisher: John Wiley & Sons
ISBN: 1119329744
Category : Science
Languages : en
Pages : 816

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Book Description
Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria

Irreversible Damage

Irreversible Damage PDF Author: Abigail Shrier
Publisher: Simon and Schuster
ISBN: 1684510465
Category : Political Science
Languages : en
Pages : 186

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Book Description
NAMED A BOOK OF THE YEAR BY THE ECONOMIST AND ONE OF THE BEST BOOKS OF 2021 BY THE TIMES AND THE SUNDAY TIMES "Irreversible Damage . . . has caused a storm. Abigail Shrier, a Wall Street Journal writer, does something simple yet devastating: she rigorously lays out the facts." —Janice Turner, The Times of London Until just a few years ago, gender dysphoria—severe discomfort in one’s biological sex—was vanishingly rare. It was typically found in less than .01 percent of the population, emerged in early childhood, and afflicted males almost exclusively. But today whole groups of female friends in colleges, high schools, and even middle schools across the country are coming out as “transgender.” These are girls who had never experienced any discomfort in their biological sex until they heard a coming-out story from a speaker at a school assembly or discovered the internet community of trans “influencers.” Unsuspecting parents are awakening to find their daughters in thrall to hip trans YouTube stars and “gender-affirming” educators and therapists who push life-changing interventions on young girls—including medically unnecessary double mastectomies and puberty blockers that can cause permanent infertility. Abigail Shrier, a writer for the Wall Street Journal, has dug deep into the trans epidemic, talking to the girls, their agonized parents, and the counselors and doctors who enable gender transitions, as well as to “detransitioners”—young women who bitterly regret what they have done to themselves. Coming out as transgender immediately boosts these girls’ social status, Shrier finds, but once they take the first steps of transition, it is not easy to walk back. She offers urgently needed advice about how parents can protect their daughters. A generation of girls is at risk. Abigail Shrier’s essential book will help you understand what the trans craze is and how you can inoculate your child against it—or how to retrieve her from this dangerous path.

Undistracted

Undistracted PDF Author: Bob Goff
Publisher: Thomas Nelson
ISBN: 1400228115
Category : Self-Help
Languages : en
Pages : 234

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Book Description
The world has never been more distracting—joy has never been more possible. You live with a massive amount of distraction: desperate headlines smartphone scrolling an endless to-do list Not to mention the nagging questions of your heart: Am I making the right decision? Am I with the right person? Will my past mistakes keep me from my best future? Through the pithy and inspiring storytelling that has endeared him to millions, New York Times bestselling author Bob Goff invites you to laugh with more gusto, dream with more confidence, and love with more intention in this disarming call to live Undistracted. Bob’s stories are like the rumble strips on the road that make you suddenly alert to how far you have drifted from your lane. From visiting friends in San Quentin to accidentally getting into a stalker’s car at the airport to establishing Uganda’s first space program, Bob shows you the way back to an audaciously attentive life. Your undistracted life is an adventure waiting to happen. What stories will you live with undistracted purpose and unstoppable joy?

The Minders

The Minders PDF Author: John Marrs
Publisher: Penguin
ISBN: 0593334744
Category : Fiction
Languages : en
Pages : 418

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Book Description
In this electrifying near-future thriller, five strangers guard government secrets, but only four can be trusted. In the 21st century, information is king. But computers can be hacked and files can be broken into - so a unique government initiative has been born. Five ordinary people have been selected to become Minders - the latest weapon in thwarting cyberterrorism. Transformed by a revolutionary medical procedure, the country's most classified information has been taken offline and turned into genetic code implanted inside their heads. Together, the five know every secret - the truth behind every government lie, conspiracy theory and cover up. In return, they're given the chance to leave their problems behind and a blank slate to start their lives anew. But not everyone should be trusted, especially when they each have secrets of their own they'll do anything to protect...

The Other People

The Other People PDF Author: C. J. Tudor
Publisher: Ballantine Books
ISBN: 1984825003
Category : Fiction
Languages : en
Pages : 354

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Book Description
A gripping thriller about a man’s quest for the daughter no one else believes is still alive, from the acclaimed author of The Chalk Man and The Hiding Place. An ID Book Club Selection • “C. J. Tudor is terrific. I can’t wait to see what she does next.”—Harlan Coben, #1 New York Times bestselling author Q: Why are you called the Other People? A: We are people just like you. People to whom terrible things have happened. We’ve found solace not in forgiveness or forgetting. But in helping each other find justice. Driving home one night, stuck behind a rusty old car, Gabe sees a little girl’s face appear in its rear window. She mouths one word: Daddy. It’s his five-year-old daughter, Izzy. He never sees her again. Three years later, Gabe spends his days and nights traveling up and down the highway, searching for the car that took his daughter, refusing to give up hope, even though most people believe she’s dead. When the car that he saw escape with his little girl is found abandoned with a body inside, Gabe must confront not just the day Izzy disappeared but the painful events from his past now dredged to the surface. Q: What sort of justice? A: That depends on the individual. But our ethos is a punishment that fits the crime. Fran and her daughter, Alice, also put in a lot of miles on the road. Not searching. Running. Because Fran knows what really happened to Gabe’s daughter. She knows who is responsible. And she knows what they will do if they ever catch up to her and Alice. Q: Can I request to have someone killed? A: If your Request is acceptable, and unless there are exceptional circumstances, we fulfill all Requests.

The Zee Files

The Zee Files PDF Author: Tina Wells
Publisher: Graphic Arts Books
ISBN: 1513134833
Category : Young Adult Fiction
Languages : en
Pages : 130

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Book Description
Fans of the bestselling Mackenzie Blue books will love this spin-off series that follows Zee's new adventures across the pond—in London! MOM'S CHOICE AWARDS® Gold Recipient 2021 American Fiction Awards Finalist, Young Adult category Winner, 2022 IndieReader Discovery Awards Mackenzie ("Zee") Blue Carmichael has never eaten fish 'n' chips, never slept away from home longer than a few nights, and knows nothing about London. But after her family relocates for her dad's new job, 13-year-old Zee leaves her old life in California behind for a new one in England. Zee lands in London and at her new boarding school, The Hollows, hoping to find new friends and jump-start her music career. All of that proves difficult between a chilly roommate, a BFF who's gone MIA, and distractions from the poshest—and cutest—student in her grade. Will Zee thrive in her new environment, and will London end up not being so bad after all? What readers are saying about The Zee Files: ★★★★★ “My daughter read this in just over a day!” ★★★★★ “Got this for my daughter for her 10th birthday! We read it together and absolutely LOVED the book!” ★★★★★ “We gave this book to my niece, and she loved it! She can't wait to see what happens next in the second book.”

Being Mortal

Being Mortal PDF Author: Atul Gawande
Publisher: Metropolitan Books
ISBN: 1627790551
Category : Social Science
Languages : en
Pages : 304

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Book Description
#1 New York Times Bestseller In Being Mortal, bestselling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering. Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified. Full of eye-opening research and riveting storytelling, Being Mortal asserts that medicine can comfort and enhance our experience even to the end, providing not only a good life but also a good end.