OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 249: Fish Cell Line Acute Toxicity - The RTgill-W1 cell line assay PDF Download
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Author: OECD
Publisher: OECD Publishing
ISBN: 9264714138
Category :
Languages : en
Pages : 51
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Book Description
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is assessed based on three fluorescent cell viability indicator dyes, measured on the same set of cells. Resazurin enters the cells in its non-fluorescent form and is converted to the fluorescent product, resorufin, by mitochondrial, microsomal or cytoplasmic oxidoreductases.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264714138
Category :
Languages : en
Pages : 51
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Book Description
The RTgill-W1 cell line assay describes a 24-well plate format fish cell line acute toxicity test using the permanent cell line from rainbow trout (Oncorhynchus mykiss) gill, RTgill-W1. After 24 h of exposure to the test chemical, cell viability is assessed based on three fluorescent cell viability indicator dyes, measured on the same set of cells. Resazurin enters the cells in its non-fluorescent form and is converted to the fluorescent product, resorufin, by mitochondrial, microsomal or cytoplasmic oxidoreductases.
Author: C. Melber
Publisher: WHO
ISBN:
Category : Medical
Languages : en
Pages : 154
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Book Description
On cover: IPCS International Programme on Chemical Safety. Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization and the World Health Organization, and produced within the framework of the Inter-organization Programme for the Sound Management of Chemicals (IOMC)
Author: Beate Escher
Publisher: IWA Publishing
ISBN: 1843393689
Category : Science
Languages : en
Pages : 273
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Book Description
Part of Water Quality Set - Buy all four books and save over 30% on buying separately! Bioanalytical Tools in Water Quality Assessment reviews the application of bioanalytical tools to the assessment of water quality including surveillance monitoring. The types of water included range from wastewater to drinking water, including recycled water, as well as treatment processes and advanced water treatment. Bioanalytical Tools in Water Quality Assessment not only demonstrates applications but also fills in the background knowledge in toxicology/ecotoxicology needed to appreciate these applications. Each chapter summarises fundamental material in a targeted way so that information can be applied to better understand the use of bioanalytical tools in water quality assessment. Bioanalytical tools in Water Quality Assessment can be used by lecturers teaching academic and professional courses and also by risk assessors, regulators, experts, consultants, researchers and managers working in the water sector. It can also be a reference manual for environmental engineers, analytical chemists, and toxicologists. Authors: Beate Escher, National Research Centre for Environmental Toxicology (EnTox), The University of Queensland, Australia, Frederic Leusch, Smart Water Research Facility (G51), Griffith University Gold Coast Campus, Australia. With contributions by Heather Chapman and Anita Poulsen
Author: Johan Eriksson
Publisher: Springer Science & Business Media
ISBN: 9048194288
Category : Law
Languages : en
Pages : 347
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Book Description
This volume presents research on current trends in chemical regulations – a fa- growing, complex, and increasingly internationalized field. The book grew out from a multidisciplinary research project entitled ‘Regulating Chemical Risks in the Baltic Sea Area: Science, Politics, and the Media’, led by Michael Gilek at Södertörn University, Sweden. This research project involved scholars and experts from natural as well as social sciences, based at Södertörn University, Swedish Royal Institute of Technology (KTH), Karolinska Institutet, and Umeå University. The project group organized a multidisciplinary research conference on chemical risk regulations, held in Stockholm, August 15–17, 2007. Most of the contributions published in this book were, in draft form, first presented at this conference. The conference, like the ensuing edited volume, expanded the geographical focus beyond the Baltic Sea area to include wider European, and to some extent also global trends. Many thanks to all project colleagues and conference participants! We are very grateful for the generous financial support received from The Foundation for Baltic and East European Studies (Östersjöstiftelsen), The Swedish Research Council Formas, and from Södertörn University. Without this support the present book would not have been possible. Special thanks to all of our fellow contributors, all of whom have submitted to- cal papers based on high-quality research. Many thanks also to Tobias Evers, who assisted us with technical editing. Finally, we are grateful for the professionalism shown by our editors at Springer.
Author: Hajime Kojima
Publisher: Springer
ISBN: 9811324476
Category : Medical
Languages : en
Pages : 136
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Book Description
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Author: Martin Wagner
Publisher: Springer
ISBN: 3319616153
Category : Science
Languages : en
Pages : 309
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Book Description
This book is open access under a CC BY 4.0 license. This volume focuses on microscopic plastic debris, also referred to as microplastics, which have been detected in aquatic environments around the globe and have accordingly raised serious concerns. The book explores whether microplastics represent emerging contaminants in freshwater systems, an area that remains underrepresented to date. Given the complexity of the issue, the book covers the current state-of-research on microplastics in rivers and lakes, including analytical aspects, environmental concentrations and sources, modelling approaches, interactions with biota, and ecological implications. To provide a broader perspective, the book also discusses lessons learned from nanomaterials and the implications of plastic debris for regulation, politics, economy, and society. In a research field that is rapidly evolving, it offers a solid overview for environmental chemists, engineers, and toxicologists, as well as water managers and policy-makers.
Author: Christian Blaise
Publisher: Springer Science & Business Media
ISBN: 1402031203
Category : Science
Languages : en
Pages : 563
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Book Description
This broad review is the first to gather comprehensive information on the complete contemporary range of toxicity testing procedures and hazard assessment procedures, which is normally scattered and difficult to find. The two-volume set provides a consistent, template-based approach, linking relevant information on background, theory and practice to each bioassay. Volume 1 covers small-scale toxicity test methods. Includes extensive glossary.
Author: Rui Goncalves
Publisher:
ISBN: 9781789180596
Category : Aquacultural engineering
Languages : en
Pages : 0
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Book Description
With the current trend for the replacement of the fishmeal content of aquaculture feeds, the issue of antinutrients contained in plant-based materials is of growing concern in aquaculture production. Mycotoxins are known antinutrients; however, their role in aquaculture feeds has still to be fully elucidated. Mycotoxins in Aquaculture is a comprehensive guide, commencing with a chapter covering general concepts, to help the reader to become familiar with the topic. The book then covers the potential implications of the presence of mycotoxins, with chapters on aquatic species defense mechanisms, mycotoxins in aquaculture and in feeds, the analysis of mycotoxin content in commodities and feeds, and fighting mycotoxins. This important book brings together the authors' experience from work with terrestrial animals to identify the targets of these antinutrients in aquatic species. It offers a new tool to whoever is approaching aquaculture in this era of finite resources.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264090932
Category :
Languages : en
Pages : 30
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Book Description
This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant ...
Author:
Publisher:
ISBN:
Category : Natural gas
Languages : en
Pages : 116
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Book Description
