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Author:
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 234
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Book Description
Author:
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 234
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Book Description
Author: J. K. Dunnick
Publisher: DIANE Publishing
ISBN: 1437902243
Category :
Languages : en
Pages : 81
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Book Description
Glycidol is used as a chemical intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, Glycidol ethers, and amines. Glycidol was nominated for carcinogenecity study by the Environmental Protection Agency (EPA). Glycidol was selected for study in the haploinsufficient p16Ink4a/p19Arf mouse because it was found to be carcinogenic in rats and mice in conventional 2-year rodent studies (NTP, 1990), but was negative in a study in p53+/- mice (Tennant et al., 1999). In this study, male and female mice received Glycidol (greater than 95% pure) by gavage for 40 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.
Author:
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ISBN:
Category : Environmental health
Languages : en
Pages : 676
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Book Description
Author: Lyn O'Brien-Nabors
Publisher: CRC Press
ISBN: 1439846154
Category : Technology & Engineering
Languages : en
Pages : 567
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Book Description
The fourth edition of Alternative Sweeteners follows the same formula as the previous three books by discussing each sweetener in terms of its characteristics. Qualities covered include means of production, physical characteristics, utility, and relative sweetness (compared to sucrose). Technical qualities covered include admixture potential, application, availability, shelf life, transport, metabolism, carcinogenicity, and other toxicity evaluation data. A new chapter on the sweetener Advantame has been added, and new contributors have updated information throughout the book. Also new is a section on how stevia sweeteners have been examined and deemed safe by the Joint FAO/WHO Expert Committee on Food Additives and the US FDA.
Author: Wanda M. Haschek
Publisher: Elsevier
ISBN: 0443161542
Category : Medical
Languages : en
Pages : 974
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Book Description
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, this book covers the toxicologic pathology of major classes of environmental toxicants. Volumes emphasize the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. This series comprises the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides updated and revised chapters for in-depth discussions of toxicologic pathology for the protection of the environment and food supplies - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Author: Disha Experts
Publisher: Disha Publications
ISBN: 9386323117
Category : Study Aids
Languages : en
Pages : 1156
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Book Description
The book NEET Guide for Physics, Chemistry & Biology has been written exclusively to help students crack the NEET exam. The book covers the 100% syllabus in Physics, Chemistry and Biology. The book follows the exact pattern of the NCERT books. Thus Physics has 29, Chemistry has 30 and Biology has 38 chapters. Each chapter contains Key Concepts, Solved Examples, Exercise with detailed solutions. The exercise contains MCQs as per the pattern of the NEET exam. This is followed by an exhaustive exercise. A real cracker, this book is complete in all aspects and is a must for every NEET aspirant. The book is also useful for AIIMS/ JIPMER/ AMU/ KCET etc.
Author: Bruce Fife
Publisher: Piccadilly Books, Ltd.
ISBN: 1936709112
Category : Health & Fitness
Languages : en
Pages : 178
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Book Description
Through the power of persuasive advertising and clever marketing, we’ve been sold on the idea that stevia is a natural herbal sweetener that is not only harmless but even health-promoting. As such, it is promoted as a better choice over sugar or other low-calorie sweeteners. Stevia has rapidly become a multimillion-dollar industry. Despite all of the marketing hype, stevia is not the innocent little herb it is made out to be—and it is not harmless. The stevia sweetener you purchase at the store is a highly refined, purified chemical that is little different from any other artificial sweetener, with many of the same drawbacks and dangers. The author’s observation of troubling adverse reactions associated with stevia led him on an investigation that uncovered disturbing facts hidden from the public, including studies that contradict the sweetener’s safety and assumed benefits. In this book, you will learn why you should never use stevia if you want to lose excess weight or control diabetes. You will also learn why all low-calorie sweeteners are potentially dangerous, and what options you have available. The information in this book comes directly from published studies, historical facts, and the author’s personal experiences. In this book you will learn that stevia is not an herb but a highly refined chemical acts like an artificial sweetener is addictive can cause digestive distress alters the gut microbiome is a gut excitotoxin promotes obesity, diabetes, and metabolic syndrome can cause allergic reactions
Author: George Azzopardi
Publisher: Springer
ISBN: 3319231170
Category : Computers
Languages : en
Pages : 821
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Book Description
The two volume set LNCS 9256 and 9257 constitutes the refereed proceedings of the 16th International Conference on Computer Analysis of Images and Patterns, CAIP 2015, held in Valletta, Malta, in September 2015. The 138 papers presented were carefully reviewed and selected from numerous submissions. CAIP 2015 is the sixteenth in the CAIP series of biennial international conferences devoted to all aspects of computer vision, image analysis and processing, pattern recognition, and related fields.
Author: Jianye Hao
Publisher: Frontiers Media SA
ISBN: 2889742946
Category : Science
Languages : en
Pages : 123
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Book Description
Author: Rudy J Richardson
Publisher: Royal Society of Chemistry
ISBN: 1782623736
Category : Science
Languages : en
Pages : 349
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Book Description
The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics. This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.
