Nonparametric Estimation of the Survival Function for Censored Data PDF Download
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Author: Lawrence Victor Rubinstein
Publisher:
ISBN:
Category : Characteristic functions
Languages : en
Pages : 146
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Book Description
Author: Lawrence Victor Rubinstein
Publisher:
ISBN:
Category : Characteristic functions
Languages : en
Pages : 146
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Book Description
Author: Guolin Zhao
Publisher:
ISBN:
Category : Mathematical statistics
Languages : en
Pages : 57
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Book Description
"Estimating survival functions has interested statisticians for numerous years. A survival function gives information on the probability of a time-to-event of interest. Research in the area of survival analysis has increased greatly over the last several decades because of its large usage in areas related to biostatistics and the pharmaceutical industry. Among the methods which estimate the survival function, several are widely used and available in popular statistical software programs. One purpose of this research is to compare the efficiency between competing estimators of the survival function. Results are given for simulations which use nonparametric and parametric estimation methods on censored data. The simulated data sets have right-, left-, or interval-censored time points. Comparisons are done on various types of data to see which survival function estimation methods are more suitable. We consider scenarios where distributional assumptions or censoring type assumptions are violated. Another goal of this research is to examine the effects of these incorrect assumptions."--Abstract from author supplied metadata.
Author: Jianguo Sun
Publisher: Springer
ISBN: 0387371192
Category : Mathematics
Languages : en
Pages : 310
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Book Description
This book collects and unifies statistical models and methods that have been proposed for analyzing interval-censored failure time data. It provides the first comprehensive coverage of the topic of interval-censored data and complements the books on right-censored data. The focus of the book is on nonparametric and semiparametric inferences, but it also describes parametric and imputation approaches. This book provides an up-to-date reference for people who are conducting research on the analysis of interval-censored failure time data as well as for those who need to analyze interval-censored data to answer substantive questions.
Author: Rupert G. Miller, Jr.
Publisher: John Wiley & Sons
ISBN: 1118031067
Category : Mathematics
Languages : en
Pages : 254
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Book Description
A concise summary of the statistical methods used in the analysis of survival data with censoring. Emphasizes recently developed nonparametric techniques. Outlines methods in detail and illustrates them with actual data. Discusses the theory behind each method. Includes numerous worked problems and numerical exercises.
Author: D.R. Cox
Publisher: Routledge
ISBN: 1351466607
Category : Mathematics
Languages : en
Pages : 216
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Book Description
This monograph contains many ideas on the analysis of survival data to present a comprehensive account of the field. The value of survival analysis is not confined to medical statistics, where the benefit of the analysis of data on such factors as life expectancy and duration of periods of freedom from symptoms of a disease as related to a treatment applied individual histories and so on, is obvious. The techniques also find important applications in industrial life testing and a range of subjects from physics to econometrics. In the eleven chapters of the book the methods and applications of are discussed and illustrated by examples.
Author: Meei Pyng Ng
Publisher:
ISBN:
Category : Estimation theory
Languages : en
Pages : 17
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Book Description
Author: John P. Klein
Publisher: Springer Science & Business Media
ISBN: 1475727283
Category : Medical
Languages : en
Pages : 508
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Book Description
Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Author: J. V. Deshpande
Publisher: World Scientific Publishing Company
ISBN:
Category : Business & Economics
Languages : en
Pages : 264
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Book Description
This book is meant for postgraduate modules that cover lifetime data in reliability and survival analysis as taught in statistics, engineering statistics and medical statistics courses. It is helpful for researchers who wish to choose appropriate models and methods for analyzing lifetime data. There is an extensive discussion on the concept and role of ageing in choosing appropriate models for lifetime data, with a special emphasis on tests of exponentiality. There are interesting contributions related to the topics of ageing, tests for exponentiality, competing risks and repairable systems. A special feature of this book is that it introduces the public domain R-software and explains how it can be used in computations of methods discussed in the book. Contents: Ageing; Some Parametric Families of Probability Distributions; Parametric Analysis of Survival Data; Nonparametric Estimation of the Survival Function; Tests of Exponentiality; Two Sample Nonparametric Problems; Proportional Hazards Model: A Method of Regression; Analysis of Competing Risks; Repairable Systems. Key Features Special emphasis on ageing and tests of exponentiality and their role in choosing appropriate models for lifetime data Extensive discussion of classical parametric and nonparametric models and relevant inference Documentation of new results in ageing, testing for competing risks and repairable systems Readership: Graduate students, academics and researchers in probability and statistics, industrial engineering, decision sciences and bioinformatics.
Author: John P. Klein
Publisher: Springer Science & Business Media
ISBN: 9401579830
Category : Mathematics
Languages : en
Pages : 446
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Book Description
Survival analysis is a highly active area of research with applications spanning the physical, engineering, biological, and social sciences. In addition to statisticians and biostatisticians, researchers in this area include epidemiologists, reliability engineers, demographers and economists. The economists survival analysis by the name of duration analysis and the analysis of transition data. We attempted to bring together leading researchers, with a common interest in developing methodology in survival analysis, at the NATO Advanced Research Workshop. The research works collected in this volume are based on the presentations at the Workshop. Analysis of survival experiments is complicated by issues of censoring, where only partial observation of an individual's life length is available and left truncation, where individuals enter the study group if their life lengths exceed a given threshold time. Application of the theory of counting processes to survival analysis, as developed by the Scandinavian School, has allowed for substantial advances in the procedures for analyzing such experiments. The increased use of computer intensive solutions to inference problems in survival analysis~ in both the classical and Bayesian settings, is also evident throughout the volume. Several areas of research have received special attention in the volume.
Author: Shabnam Fani
Publisher:
ISBN:
Category : Failure time data analysis
Languages : en
Pages : 126
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Book Description
The main problem studied in this thesis is to analyse and model time-to- event data, particularly when the survival times of subjects under study are not exactly observed. One of the primary tasks in the analysis of survival data is to study the distribution of the event times of interest. In order to avoid strict assumptions associated with a parametric model, we resort to nonparametric methods for estimating a function. Although other nonparametric approaches, such as Kaplan-Meier, kernel-based, and roughness penalty methods, are popular tools for solving function estimation problems, they suffer from some non-trivial issues like the loss of some important information about the true underlying function, difficulties with bandwidth or tuning parameter selection. In contrast, one can avoid these issues at the cost of enforcing some qualitative shape constraints on the function to be estimated. We confine our survival analysis studies to estimating a hazard function since it may make a lot of practical sense to impose certain shape constraints on it. Specifically, we study the problem of nonparametric estimation of a hazard function subject to convex shape restrictions, which naturally entails monotonicity constraints. In this thesis, three main objectives are addressed. Firstly, the problem of nonparametric maximum-likelihood estimation of a hazard function under convex shape restrictions is investigated. We introduce a new nonparametric approach to estimating a convex hazard function in the case of exact observations, the case of interval-censored observations, and the mixed case of exact and interval-censored observations. A new idea to handle the problem of choosing the minimum of a convex hazard function estimate is proposed. Based on this, a new fast algorithm for nonparametric hazard function estimation under convexity shape constraints is developed. Theoretical justification for the convergence of the new algorithm is provided. Secondly, nonparametric estimation of a hazard function under smoothness and convex shape assumptions is studied. Particularly, our nonparametric maximum-likelihood approach is generalized for smooth estimation of a function by applying a higher-order smoothness assumption of an estimator. We also evaluate the performance of the estimators using simulation studies and real-world data. Numerical studies suggest that the shape-constrained estimators generally outperform their unconstrained competitors. Moreover, the empirical results indicate that the smooth shape-restricted estimator has more capability to model human mortality data compared to the piecewise linear continuous estimator, specifically in the infant mortality phase. Lastly, our nonparametric estimation of a hazard function approach under convex shape restrictions is extended to the Cox proportional hazards model. A new algorithm is also developed to estimate both convex baseline hazard function and the effects of covariates on survival times. Numerical studies reveal that our new approaches generally dominate the traditional partial likelihood method in the case of right-censored data and the fully semiparametric maximum likelihood estimation method in the case of interval-censored data. Overall, our series of studies show that the shape-restricted approach tends to provide more accurate estimation than its unconstrained competitors, and further investigations in this direction can be highly fruitful.
