Non-human Primate Models of Psychiatric Disorders PDF Download
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Author: Rafael S. Maior
Publisher: Frontiers Media SA
ISBN: 2889719847
Category : Science
Languages : en
Pages : 101
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Book Description
Author: Rafael S. Maior
Publisher: Frontiers Media SA
ISBN: 2889719847
Category : Science
Languages : en
Pages : 101
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category : Mental illness
Languages : en
Pages : 123
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Book Description
Author: Carlos Tomaz
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Thomas Burbacher
Publisher: Academic Press
ISBN: 0080554067
Category : Medical
Languages : en
Pages : 480
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Book Description
The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising in the United States. Although estimates of the prevalence of these disorders vary, figures from the CDC indicate that 4% of all school age children are developmentally disabled. During infancy, many important milestones in behavioral development are shared between human and nonhuman primates. Learning more about the causes of abnormal development in monkeys has provided important insights into the mechanisms underlying neurodevelopmental disabilities in human infants. This book documents the latest research not commonly found in other references, and provides a comprehensive look at the results from decades of work with nonhuman primates as it relates to child development and disability. Includes hot topics such as early chemical exposures, immunological influences on development, low birth weight, endocrine disrupters, pediatric AIDS, origin of childhood psychopathologies and assisted reproductive technology Represents the significant body of work accumulated since funding for research on developmental disabilities has increased substantially in recent years
Author: W. Richard Dukelow
Publisher: CRC Press
ISBN: 135109193X
Category : Medical
Languages : en
Pages : 313
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Book Description
While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309488737
Category : Medical
Languages : en
Pages : 91
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Book Description
To examine the promise, concerns, and challenges related to neuroscience research using genetically modified nonhuman primates, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop on October 4, 2018, bringing together an international group of experts and stakeholders representing academia, industry, laboratory animal management, disease-focused foundations, and federal agencies. The workshop was designed to explore the current state and future promise of research using genetically modified nonhuman primate models of disease to understand the complex functions of the brain that control behavior, movement, and cognition in both health and disease states. This publication summarizes the presentations and discussions from the workshop.
Author: Dario Maestripieri
Publisher: University of Chicago Press
ISBN: 0226501213
Category : Science
Languages : en
Pages : 206
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Book Description
Judged by population size and distribution, homo sapiens are clearly the most successful primates. A close second, however, would be rhesus macaques, who have adapted to—and thrived in—such diverse environments as mountain forests, dry grasslands, and urban sprawl. Scientists have spent countless hours studying these opportunistic monkeys, but rhesus macaques have long been overshadowed in the public eye by the great apes, who, because of their greater intelligence, are naturally assumed to have more to teach us, both about other primates and about humans as well. Dario Maestripieri thinks it is high time we shelve that misperception, and with Macachiavellian Intelligence he gives rhesus macaques their rightful turn in the spotlight. The product of more than twenty years studying these fascinating creatures, Macachiavellian Intelligence caricatures a society that is as much human as monkey, with hierarchies and power struggles that would impress Machiavelli himself. High-status macaques, for instance, maintain their rank through deft uses of violence and manipulation, while altruism is almost unknown and relationships are perpetually subject to the cruel laws of the market. Throughout this eye-opening account, Maestripieri weds his thorough knowledge of macaque behavior to his abiding fascination with human society and motivations. The result is a book unlike any other, one that draws on economics as much as evolutionary biology, politics as much as primatology. Rife with unexpected connections and peppered with fascinating anecdotes, Macachiavellian Intelligence has as much to teach us about humans as it does about macaques, presenting a wry, rational, and wholly surprising view of our humanity as seen through the monkey in the mirror.
Author: National Academies Of Sciences Engineeri
Publisher: National Academies Press
ISBN: 9780309699365
Category : Medical
Languages : en
Pages : 0
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Book Description
Nonhuman primates represent a small fraction of animals used in biomedical research, but they remain important research models due to their similarities to humans with respect to genetic makeup, anatomy, physiology, and behavior. Limitations in the availability of nonhuman primates have been exacerbated by the COVID-19 pandemic and recent restrictions on their exportation and transportation, impacting National Institutes of Health (NIH)-funded research necessary for both public health and national security. Additionally, there is continued interest in understanding whether and how nonanimal models can be used to answer scientific questions for which nonhuman primates are currently used. At the direction of the U.S. Congress, NIH asked the National Academies of Sciences, Engineering, and Medicine to convene an expert committee to conduct a landscape analysis of current and future use of nonhuman primates in NIH-supported biomedical research, as well as opportunities for new approach methodologies to complement or reduce reliance on nonhuman primate models. This report provides the committee findings and conclusions.
Author: Huifang Chen
Publisher:
ISBN: 9781536199147
Category : Primates as laboratory animals
Languages : en
Pages : 0
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Book Description
"Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and social skills, the use of these animals in biomedical research is debated more and more. Although it is acknowledged that in specific research areas NHP are still essential, it is recognized that the use of these animals can only be done under strict conditions under the most optimal welfare aspects. Welfare aspects include housing conditions, non-invasive methods and application of the 3Rs policy. Although many refinement methods have been described in nationally and internationally accepted guidelines on animal laboratory practice, recognition of the guidelines is unfortunately not universal. The present book covers a wide range of NHP models in preclinical research and welfare issues. The following chapters will cover: refinement of the use of NHP in biomedical research; NHP ethics and regulations in Europe; biological basis differences in the human and NHP; the major histocompatibility complex (MHC) immunology in NHP; stem cell biology in NHP; neuro and gliogenesis in an NHP ischemia stroke model; NHP models in autoimmune disease, organ transplantation and infectious disease research; viral diseases in NHP; NHP models in Parkinson's disease, in neurodegenerative disorders research and in cardio-cerebrovascular disease research; islet transplantation; ophthalmic diseases research and neurophysiology in NHP; transgenic engineering in NHP; NHP models of cancers; NHP models in respiratory disease research; NHP models in clinical and non-clinical pharmacology; NHP models in lung transplantation; and aging research in NHP. This book encapsulates a large volume of knowledge scientists have achieved in the field of nonhuman primate models in preclinical research. The editors have invited experts from the United States, Canada, and Europe to contribute 23 chapters in their respective fields of their expertise"--
Author: F. R. Akins
Publisher: Springer
ISBN:
Category : Juvenile Nonfiction
Languages : en
Pages : 328
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Book Description
The present volume represents the result of two years of work originally begun as a fifteen-member student project under my supervision at NASA - Ames Research Center, Moffett Field, Calif ornia. As a means of acquainting team members with previous research related to our NASA experiments with long-term isolation and confine ment effects upon nonhuman primate behavior a weekly meeting was arranged for students to orally present abstracts of various articles they had read. As the number of references increased we decided to expand our efforts through several computer searches of the psychological, biological, anthropological, and medical liter ature. Upon completion of our experiments at NASA, three of the team members and myself decided to take this basic foundation, up date, expand and otherwise polish it into the present comprehensive reference tool we feel confident will be of value to investigators and scholars interested in the broad topic of nonhuman primate development as affected by early environmental influences. While ours is the only bibliography of this literature which includes both abstracts and indexing, several previous publications are worth noting as we found them particularly helpful in our own work. Those bibliographies, compiled by Agar and Mitchell (1973), Stoffer and Stoffer (1976), and Roy (1976, 1977), are excellent. In addition to the articles cited in these sources we have added approximately 400 more articles with abstracts and indexing.
