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Author: Erling Norrby
Publisher: World Scientific
ISBN: 9811261342
Category : Science
Languages : en
Pages : 459
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Book Description
The present book discusses the Nobel Prizes in physiology or medicine from 1969 to 1971. The 1969 prize recognized Max Delbrück, Alfred Hershey and Salvador Luria. Their pioneering studies of viruses infecting bacteria, bacteriophages, from the mid-1940s through the 1950s laid the foundation for the wide field of molecular biology. The nature of the gene was finally understood. Insights into the biochemistry of the critical information molecules, the nucleic acids, opened wide vistas for interpreting their expression and the interaction of their product with other gene products.The contact between the endings of a nerve and a target cell, the synapse, has always stirred the imagination of scientists. A number of the insights gained have been highlighted by Nobel Prizes in physiology or medicine. In 1970 the prize recognized Bernard Katz, Ulf von Euler and Julius Axelrod. They had revealed how signaling substances in the nerve terminals were stored in packages, released by membrane fusion and inactivated or reused by particular metabolic events.The recipient of the 1971 Nobel Prize in physiology or medicine was a single scientist, Earl Sutherland. He had identified critical molecules in cells that allow signals elicited at their surface via a number of internal steps to influence the expression of specific genes in the nucleus. The new kind of information transmitting molecules were referred to as 'secondary messengers'. They represent a critical part of a highly complex network of signaling controlling the operative conditions of the cell by adjustments of the so-called intermediary metabolism.The widening insights into functions of specialized cells and their complex interactions have led to the development of many kinds of remedies.
Author: Erling Norrby
Publisher: World Scientific
ISBN: 9811261342
Category : Science
Languages : en
Pages : 459
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Book Description
The present book discusses the Nobel Prizes in physiology or medicine from 1969 to 1971. The 1969 prize recognized Max Delbrück, Alfred Hershey and Salvador Luria. Their pioneering studies of viruses infecting bacteria, bacteriophages, from the mid-1940s through the 1950s laid the foundation for the wide field of molecular biology. The nature of the gene was finally understood. Insights into the biochemistry of the critical information molecules, the nucleic acids, opened wide vistas for interpreting their expression and the interaction of their product with other gene products.The contact between the endings of a nerve and a target cell, the synapse, has always stirred the imagination of scientists. A number of the insights gained have been highlighted by Nobel Prizes in physiology or medicine. In 1970 the prize recognized Bernard Katz, Ulf von Euler and Julius Axelrod. They had revealed how signaling substances in the nerve terminals were stored in packages, released by membrane fusion and inactivated or reused by particular metabolic events.The recipient of the 1971 Nobel Prize in physiology or medicine was a single scientist, Earl Sutherland. He had identified critical molecules in cells that allow signals elicited at their surface via a number of internal steps to influence the expression of specific genes in the nucleus. The new kind of information transmitting molecules were referred to as 'secondary messengers'. They represent a critical part of a highly complex network of signaling controlling the operative conditions of the cell by adjustments of the so-called intermediary metabolism.The widening insights into functions of specialized cells and their complex interactions have led to the development of many kinds of remedies.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Lee B. Kass
Publisher: CRC Press
ISBN: 104003215X
Category : Science
Languages : en
Pages : 411
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Book Description
This biography of Nobel Laureate Barbara McClintock (1902-1992) places her life and work in its social, scientific and personal context. The author examines the development of Barbara McClintock’s scientific work and her influence upon individuals and upon the fields of cytogenetics and evolutionary biology in the period from 1902 to the present. The history documents years of McClintock’s notable and lauded scientific work long before she discovered and named transposable elements in the mid-1940s for which she ultimately received the Nobel Prize. The biography employs documented evidence to expose, demystify, and provide clarity for legends and misinterpretations of McClintock’s life and work. Key Features Exposes and demystifies myths and legends told about McClintock’s time in Missouri Clarifies the changing language of genes and genetics Places in perspective the history of McClintock’s research Documents McClintock’s family and early life before college Provides documented details of McClintock’s time in Nazi Germany
Author: Renato Dulbecco
Publisher:
ISBN:
Category : Biology
Languages : en
Pages : 482
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Book Description
Nobel laureate Renato Dulbecco presents a fascinating overview of the current state of information about life processes, ranging from the characteristics and activities of DNA to sexuality, practical aspects of genetics, communication between cells and between organisms, and the effects of drugs on the brain. He concludes with a provocative discussion of biology and human affairs in which he poses questions about brain programming and its relationship to accountability, freedom of choice, and the future. Dr. Dulbecco's book will be of interest to general readers as well as to specialists in the field.
Author: Erling Norrby
Publisher: World Scientific
ISBN: 9813144661
Category : Science
Languages : en
Pages : 580
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Book Description
The present book discusses the prizes in physiology or medicine 1963-65. The 1963 prize recognized milestone discoveries in the field of neurosciences, the way electrical impulses are generated and spread in nerves. The impressive developments of insights into tantalizing brain functions, like consciousness and memory, is discussed in the perspective of prizes both before and after the 1963 prize. The prize in 1964 marked the advanced biochemical venture that led to a full understanding of the synthesis of cholesterol, a central molecule for providing flexibility of the membranes of the trillions of cell in our body. The importance of this molecule for the appearance of cardiovascular diseases and the possibilities to prevent them is presented in the light of other prizes earlier and later in this field. The 1965 prize recognized three impressive French intellectuals, Lwoff, Monod and Jacob. Their contributions allowed the full maturation of the initial phase of the emerging field of molecular biology. The comprehension of the information flow from DNA via RNA to proteins was the source of a revolution of life sciences and of medicine.
Author: Harold Varmus
Publisher: W. W. Norton & Company
ISBN: 0393073564
Category : Biography & Autobiography
Languages : en
Pages : 330
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Book Description
A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” (American Scientist), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.
Author: Erling Norrby
Publisher: World Scientific
ISBN: 9814299367
Category : Science
Languages : en
Pages : 334
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Book Description
The Nobel Prizes m natural sciences have achieved the reputation of being the ultimate accolade for scientific achievements. This honk gives a unique insight into the selection of Nobel Prize recipients, in particular the life sciences. The evolving mechanisms of selection of prize recipients are illustrated by reference to archives, which have remained secret for 1) years. Many of the prizes subjected to particular evaluation concern awards given for discoveries in the field of infectious diseases and the interconnected field of genetics. The book illustrates the individuals and environments that are conducive to scientific creativity. Nowhere is this enigmatic activity'-- the mime mover in advancing the human condition highlighted as lucidly as by identification individuals worthy of Nobel Prizes. --Book Jacket.
Author: Erling Norrby
Publisher: World Scientific
ISBN: 9811205566
Category : Science
Languages : en
Pages : 423
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Book Description
The present book discusses the Nobel Prizes in physiology or medicine 1966-68. The 1966 prize recognized that viruses may be involved in cancer formation. Later studies revealed that these kinds of infectious agents could pick up and transmit cellular genes of importance for regulation of cellular growth. It was then possible to recognize that many genes of this kind could be involved in the formation of cancer. The disease was found to represent the dark side of evolution. As a consequence of this insight new means of treatment fortunately have been developed.The rear parts of the eyes are extensions of the central nervous system. They have a fascinating intrinsic complexity, the neurophysiology and biochemistry of which has been progressively analyzed. These revealing studies concern both our capacity to distinguish different colors and also our possibility to see in the dark. The Prize in 1967 identified seminal contributions in this wide field by Ragnar Granit, Haldan Hartline and George Wald.The 1968 Prize is distinct in its recognition of Robert Holley, Ghobind Khorana and Marshall Nirenberg, who in different ways had contributed to the cracking of the genetic code. Insights into the language used by Nature, since the dawn of cellular life some 4.6 billion years ago, have completely revolutionized modern life sciences. The capacity to read and also to write the books of life has defined new kinds of science, deepening our understanding of the magic of evolution and opened the possibilities for molecular medicine by understanding the genetic background to diseases, not least cancer.Related Link(s)
Author: Shane Crotty
Publisher: Univ of California Press
ISBN: 0520239040
Category : Biography & Autobiography
Languages : en
Pages : 303
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Book Description
A biography of one of America's most famous and important molecular biologists.
Author: N. James Maclachlan
Publisher: Academic Press
ISBN: 012801170X
Category : Medical
Languages : en
Pages : 603
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Book Description
Fenner's Veterinary Virology, Fifth Edition, is a comprehensive reference of global importance that features coverage on viral agents, viral diseases of animals, and newly emerging viral zoonotic diseases. It is an excellent first port of call for researchers and students alike, presenting the fundamental principles of virology, virus structure, genome replication, and viral diseases, while also focusing on the topics' clinical aspects. Organized on a taxonomic basis, readers can quickly understand how the virus (or the viral diseases) fits into the bigger picture of the virus genus and family. The basic information about each virus, such as disease, transmission, control, and treatment are useful for veterinary students and clinicians for their practices in disease management and prevention. - Revised and updated to include taxonomic organization changes and topical information - Provides a comprehensive overview of viruses and viral diseases of veterinary significance - Includes global contributions from thought leaders - Emphasizes new and emerging viral diseases
