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Author: Arthur Sasahara
Publisher: CRC Press
ISBN: 9780824707958
Category : Medical
Languages : en
Pages : 720
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Book Description
Presents new chapters discussing the latest research on low-molecular-weight heparins, as well as agents such as pentasaccharide, TFP1, soluble thrombomodulin, and alfimeprase. Completely revised and expanded throughout, New Therapeutic Agents in Thrombosis and Thrombolysis details strategies to target conventional and recently characterized pathways of hemostasis minimize the prothrombotic function of activated platelets assess the biochemical and pharmacological effects of antithrombotic agents and discusses the use of animal models for determination of antithrombotic drug efficacy antithrombotic therapy as a key component of cardiovascular disease management the management of thromboembolic events in children and pregnant women Supplemented with more than 2000 contemporary references, New Therapeutic Agents in Thrombosis and Thrombolysis is an authoritative source for cardiologists, internists, primary care physicians, vascular medicine specialists, cardiovascular and vascular surgeons, hematologists, pulmonologists, critical care physicians, pharmacologists, pharmaceutical researchers, and fellows, residents, and graduate and medical school students in these disciplines.
Author: Arthur Sasahara
Publisher: CRC Press
ISBN: 9780824707958
Category : Medical
Languages : en
Pages : 720
Get Book Here
Book Description
Presents new chapters discussing the latest research on low-molecular-weight heparins, as well as agents such as pentasaccharide, TFP1, soluble thrombomodulin, and alfimeprase. Completely revised and expanded throughout, New Therapeutic Agents in Thrombosis and Thrombolysis details strategies to target conventional and recently characterized pathways of hemostasis minimize the prothrombotic function of activated platelets assess the biochemical and pharmacological effects of antithrombotic agents and discusses the use of animal models for determination of antithrombotic drug efficacy antithrombotic therapy as a key component of cardiovascular disease management the management of thromboembolic events in children and pregnant women Supplemented with more than 2000 contemporary references, New Therapeutic Agents in Thrombosis and Thrombolysis is an authoritative source for cardiologists, internists, primary care physicians, vascular medicine specialists, cardiovascular and vascular surgeons, hematologists, pulmonologists, critical care physicians, pharmacologists, pharmaceutical researchers, and fellows, residents, and graduate and medical school students in these disciplines.
Author: Jane E. Freedman
Publisher: CRC Press
ISBN: 1420069241
Category : Medical
Languages : en
Pages : 714
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Book Description
As the number of patients with thrombosis and thrombolysis increases, there is a critical need for clinicians to learn the latest scientific discoveries and treatment options. This timely Third Edition is a comprehensive text for cardiologists, hematologists, and pharmacologists in need of a resource on current agent development technology for trea
Author: Patrick D. Lyden
Publisher: Springer Science & Business Media
ISBN: 1592599338
Category : Medical
Languages : en
Pages : 372
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Book Description
It often takes time for a new therapeutic modality to mature into an accepted treatment option. After initial approval, new drugs, devices, and procedures all go through this process until they become “vetted” by the scientific community as well as the medical community at large. Thrombolysis for treatment of stroke is no exception. Thrombolytic Therapy for Acute Stroke, Second Edition comes four years after the first edition and provides a very comprehensive, updated perspective on the use of intravenous rt-TPA in acute stroke. The authors provide longer term follow-up on the pivotal clinical trials that led to Food and Drug Administration approval, data concerning phase 4 trials in larger numbers of patients, and, most importantly, the community experience that has accumulated since its release. They add to this the latest promising information concerning intra-arterial thrombolysis, which is still under investigation and more speculative sections concerning possible new avenues of clinical research such as combining intravenous thr- bolysis with neuroprotective therapies or intra-arterial thrombolysis. A wealth of factual information is supplemented by chapters containing sage opinion from Drs. Lyden and Caplan concerning the logistical, economic, and procedural issues that have been generated since the advent of this technology. Importantly, diagnosis does not take a back seat to therapeutics as illustrated by sections devoted to eva- ation of the stroke patient, very useful illustrative cases and clinical comments, and chapters on the latest in imaging as applied to this field.
Author: A. Geibel
Publisher: Springer Science & Business Media
ISBN: 3642511902
Category : Medical
Languages : en
Pages : 202
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Book Description
The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
Author: Allen Cato
Publisher: CRC Press
ISBN: 0824744802
Category : Medical
Languages : en
Pages : 451
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Book Description
Aimed at those already involved in drug development or those considering entering the field, Clinical Drug Trials and Tribulations, Second Edition comprehensibly addresses the new, day-to-day challenges of drug development with valuable assessments of the areas affecting the conduction of nonclinical and clinical studies. Addressing which decisions should be made during drug development, this updated and expanded text/reference carefully guides readers through the various trials and tribulations that emerge phase-by-phase and are pertinent to all levels of pharmaceutical or clinical drug management. Bringing together the latest information on drug development, the Second Edition contains: new material on... international regulation and deregulation venture capitalist investment the IND process informed consent changes in manufacturing and updated and extended coverage of... pediatric drug trial design the advantages and disadvantages of orphan drug designations the maximization of package inserts for marketing post approval safety surveillance withdrawals from the drug market Clinical Drug Trials and Tribulations, Second Edition will prove an invaluable reference for pharmacologists, pharmacists, clinical chemists, clinical coordinators, clinical monitors, government drug regulatory personnel, and bioethicists as well as a useful text for medical or pharmacy school courses on pharmaceutical development and research.
Author: Carlos Jerjes-Sánchez
Publisher: Springer
ISBN: 331919707X
Category : Medical
Languages : en
Pages : 247
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Book Description
This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients requiring thrombolysis are identified; and the use of thrombolytic therapy in special situations such as in in-transit thrombus and pregnancy. Focusing on peripheral intravenous thrombolysis, which can performed safely and effectively in emergency departments, hospital wards, and intensive critical care units in tertiary and community hospitals, Thrombolysis in Pulmonary Embolism is a valuable resource for cardiologists, pulmonologists, and internists.
Author: Alok A. Khorana
Publisher: CRC Press
ISBN: 1420048007
Category : Medical
Languages : en
Pages : 290
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Book Description
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Author: R. Gilberto González
Publisher: Springer Science & Business Media
ISBN: 3642127517
Category : Medical
Languages : en
Pages : 299
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Book Description
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Author: Wilbert Aronow
Publisher: CRC Press
ISBN: 0824750950
Category : Medical
Languages : en
Pages : 1014
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Book Description
Certain to become the most trusted source in geriatric cardiology, this Third Edition compiles the latest studies and expertise on the epidemiology, pathophysiology, and management of cardiovascular disease in the elderly patient, tracking the rapid pace of innovation in the field with in-depth explorations of the most recent clinical trials and advances in vascular biology, cardiology, and cardiovascular surgery for influential developments in disease prevention and management.
Author: Stavros V. Konstantinides
Publisher: Springer Science & Business Media
ISBN: 1597452874
Category : Medical
Languages : en
Pages : 273
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Book Description
This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.
